| Domvs London (Canfield Place) Ltd | Construction | 2020 |
| Douglas Casey Property Services Limited | Real estate | 2023 |
| Dovemere Ltd | Construction | 2018 |
| DP Project Services Limited | Other services | 2009 |
| Drake Associates Limited | Professional & scientific | 2005 |
| Drinkeasy Limited | Manufacturing | 2024 |
| Driven by Liberty Limited | Transport & logistics | 2019 |
| Drjks Ltd | Financial services | 2026 |
| Dubbarry Properties Limited | Real estate | 2020 |
| Dusk 7 Events Limited | Arts & recreation | 2021 |
| Dynamic Education Solutions Ltd | Professional & scientific | 2018 |
| Dynamic Golf Limited | Arts & recreation | 2000 |
| E & B Barlow Limited | Construction | 2014 |
| E Clifford Engineering Limited | Professional & scientific | 2024 |
| Earlswood Trading Limited | Wholesale & retail | 2020 |
| Eastwood NDT & Ropes Access Limited | Other services | 2012 |
| Easy Shop Glossop Ltd | Wholesale & retail | 2025 |
| Echo Building (Liverpool) Limited | Real estate | 2018 |
| Echo Liverpool Limited | Real estate | 2018 |
| Eco Dog Wash Ltd | Other services | 2025 |
| Edace Ltd | Wholesale & retail | 2025 |
| Edge Engineering Limited | Professional & scientific | 2007 |
| Eesa Medical Services Limited | Health & social care | 2009 |
| Eica Engineering Ltd | Professional & scientific | 2012 |
| EL Blake Consulting Limited | Professional & scientific | 2025 |
| EL Gatewood Ltd | Hospitality | 2026 |
| Elaine Huskisson Ltd | Health & social care | 2026 |
| Electricjoinery Ltd | Construction | 2025 |
| Elegantly Radiant Aesthetics Limited | Other services | 2025 |
| Eleven Integration Limited | Information & communication | 2014 |
| Elite Climate Solutions Ltd | Energy | 2021 |
| Ellcas Limited | Real estate | 2018 |
| ELM Risk Solutions Ltd | Financial services | 2026 |
| ELM Strategies Ltd | Professional & scientific | 2025 |
| EMF Computing Limited | Information & communication | 2009 |
| Eminent Driveways Groundwork Limited | Construction | 2025 |
| Eminent Driveways Resin Bound Limited | Construction | 2025 |
| EML Digital Ltd | Information & communication | 2024 |
| Emmy Beech Ltd | Other services | 2015 |
| Empire Projects Ltd | Hospitality | 2026 |
| Empire Strikes Back Ltd | Hospitality | 2024 |
| Energywise Heating Limited | Construction | 2021 |
| Engineering Solutions Consultancy Ltd | Professional & scientific | 2023 |
| Enotom Ltd | Real estate | 2023 |
| Ensevo Limited | Professional & scientific | 2014 |
| Ental Limited | Wholesale & retail | 2014 |
| Entronet Limited | Information & communication | 2025 |
| EOE Agency Limited | Wholesale & retail | 2020 |
| Esel Services Ltd | Construction | 2016 |
| Esquire Glass(Manchester)Limited | Manufacturing | 1970 |
| Essence Glossop Limited | Hospitality | 2024 |
| Etherow Stone Ltd | Wholesale & retail | 2015 |
| Everest Bespoke Landscapes Limited | Administrative & support | 2026 |
| Everest Garden Landscapes Ltd | Administrative & support | 2024 |
| Everybody Media Ltd | Information & communication | 2022 |
| Executive Room Rental Limited | Real estate | 2013 |
| Express Contract Cleaners Limited | Administrative & support | 2014 |
| Extinguisher Hire Limited | Administrative & support | 2008 |
| Extra Timeuk Community Interest Company | Administrative & support | 2023 |
| EYE Candy Productions Ltd | Arts & recreation | 2014 |
| EZ Build Limited | Construction | 2021 |
| F&D ARM23 Limited | Hospitality | 2023 |
| FAB Guard Limited | Financial services | 2023 |
| Fairway Motors (High Peak) Limited | Wholesale & retail | 2016 |
| Fastpac Contract Packaging Limited | Administrative & support | 2025 |
| Fidavia Limited | Financial services | 2025 |
| Fidjit Ltd | Education | 2021 |
| Fifth Wall Investments Limited | Real estate | 2016 |
| FIGURE8 Architects Limited | Professional & scientific | 2025 |
| FIN NDT Limited | Construction | 2005 |
| Finger Post (Stockport) Ltd | Hospitality | 2018 |
| Fingerprints Limited | Manufacturing | 2000 |
| Fire Safety Associates Limited | Public administration | 2022 |
| Firkin Leisure Limited | Hospitality | 2024 |
| First Choice Network Services Ltd | Information & communication | 2024 |
| Firwood Court Glossop (Management) Limited | Households | 1994 |
| Fisher Marshall Decorators Limited | Construction | 2025 |
| Fitzfire Pipe Services Ltd | Construction | 2016 |
| FL Holdings (Newco 2) Limited | Professional & scientific | 2020 |
| Flair Flooring Group Limited | Wholesale & retail | 2014 |
| Flair Flooring Supplies International Limited | Wholesale & retail | 2013 |
| Flair Flooring Supplies Limited | Manufacturing | 1982 |
| Flair Properties Limited | Real estate | 2014 |
| Flat-Out Competitions Limited | Administrative & support | 2026 |
| Flat-Out Media Ltd | Professional & scientific | 2019 |
| Fletcher Civil Engineering Ltd | Information & communication | 2020 |
| Flexmoor Properties Limited | Real estate | 2016 |
| Flory and Forest Limited | Manufacturing | 2016 |
| Fluid Equipment Services Limited | Wholesale & retail | 1984 |
| Fluorochem Limited | Wholesale & retail | 1986 |
| FM Glossop Ltd | Hospitality | 2025 |
| FMB Structural Builders Limited | Construction | 2023 |
| FMT Aerospace Limited | Financial services | 2019 |
| Fogell Rigging & Inspection Limited | Professional & scientific | 2010 |
| Fonex Glossop Ltd | Wholesale & retail | 2025 |
| Forefront Consulting Ltd | Professional & scientific | 2025 |
| Forktruck Trader.Com Limited | Wholesale & retail | 2011 |
| Fortknox Systems Limited | Information & communication | 1994 |
| Four Corners Art Ltd | Wholesale & retail | 2025 |
| FOX NW Limited | Hospitality | 2025 |