| Restoration Projects Limited | Construction | 2013 |
| Restore Counselling Services Ltd | Health & social care | 2025 |
| Revup Finance Limited | Financial services | 2024 |
| Reymax Limited | Real estate | 2023 |
| Reymax Properties Limited | Real estate | 2023 |
| Rfmaterials Limited | Professional & scientific | 2012 |
| RGN Builders Ltd | Construction | 2020 |
| Ribble Valley Living Limited | Wholesale & retail | 2021 |
| Richard Glover Management Ltd | Construction | 2019 |
| Ridgeline Property Preservation Ltd | Construction | 2025 |
| Rigging & Lifting Assessments Ltd | Construction | 2024 |
| Risk and Business Consultants Limited | Professional & scientific | 2009 |
| Ritzmart Investment Ltd | Wholesale & retail | 2014 |
| RJ Skin Clinic Limited | Health & social care | 2018 |
| Rj/Hathaway Ltd | Administrative & support | 2025 |
| RKM Care Services Ltd | Health & social care | 2018 |
| RMD Contractors Ltd | Construction | 2009 |
| RMF Technical Limited | Manufacturing | 2022 |
| Robert Thompson Hard & Soft Landscaping Ltd | Administrative & support | 2012 |
| ROC Automation Solutions Ltd | Information & communication | 2024 |
| Room to Build Ltd | Real estate | 2026 |
| Roots and Shoots Tree Surveys Limited | Agriculture & fishing | 2023 |
| Rosellie Limited | Professional & scientific | 2019 |
| Rowarth Realty Ltd | Real estate | 2025 |
| Rowtell Property Developments Limited | Construction | 2015 |
| RRQ Distributions Ltd | Wholesale & retail | 2025 |
| Rugcycle Limited | Wholesale & retail | 2023 |
| Rumfusion Ltd | Wholesale & retail | 2020 |
| Rushmere Management Solutions Ltd | Professional & scientific | 2015 |
| Rust Manchester Limited | Information & communication | 2025 |
| Ryder Electrical Solutions Ltd | Construction | 2017 |
| S & S Retail Developments Limited | Wholesale & retail | 2013 |
| S J Taylor & Sons Ltd | Real estate | 2024 |
| S Wilson Property Developments Limited | Real estate | 2012 |
| S Zone UK Private Ltd | Wholesale & retail | 2023 |
| SA Lettings High Peak Ltd | Real estate | 2021 |
| Sacred Art Limited | Other services | 2012 |
| Safeas Ltd | Professional & scientific | 2024 |
| Safety Management Systems Northwest Ltd | Professional & scientific | 2018 |
| Sage & Bloom Aesthetics Ltd | Other services | 2025 |
| Sals Care and Support Ltd | Health & social care | 2025 |
| Sanders Couriers UK Limited | Transport & logistics | 2022 |
| Sandra’S the Enchanted Florist Ltd | Wholesale & retail | 2024 |
| Saradipity Events Ltd | Administrative & support | 2014 |
| Sarah Elisabeth Health Ltd | Health & social care | 2022 |
| SAS Build Pro Ltd | Construction | 2026 |
| Scale & IVY Limited | Professional & scientific | 2025 |
| Scandia Spaces Ltd | Wholesale & retail | 2020 |
| Scandivans Ltd | Wholesale & retail | 2022 |
| SCC Beauty Schools Ltd | Education | 2019 |
| Scimove Consultancy UK Limited | Professional & scientific | 2026 |
| Scott Thornton Roofing Contractors Ltd. | Construction | 2017 |
| Scrabble Media Ltd | Information & communication | 2023 |
| SD Supplies Limited | Wholesale & retail | 2020 |
| Select (Baker ST.) Limited | Real estate | 2020 |
| Select (Baker ST.) Residential Limited | Construction | 2021 |
| Select (Co-Op) Limited | Real estate | 2021 |
| Select Birmingham Limited | Real estate | 2018 |
| Select Breadsall Limited | Real estate | 2026 |
| Select Breadsall Opco Limited | Hospitality | 2026 |
| Select Chepstow Limited | Real estate | 2026 |
| Select Chepstow Opco Limited | Hospitality | 2026 |
| Select Construction Cheshire Ltd | Construction | 2019 |
| Select Maidstone Limited | Real estate | 2026 |
| Select Maidstone Opco Limited | Hospitality | 2026 |
| Select Mere Resort Limited | Real estate | 2022 |
| Select UK Investments Limited | Financial services | 2026 |
| Select Valley Limited | Real estate | 2025 |
| SEN Assess Ltd | Education | 2024 |
| SEVENTY7 North Limited | Professional & scientific | 2018 |
| SEVENTY7 South Limited | Professional & scientific | 2018 |
| Shackleton Building Services Ltd | Construction | 2024 |
| Shafi Cars Ltd | Wholesale & retail | 2011 |
| Shawfit Tyres Limited | Other services | 2002 |
| Shaws Automotive Supplies Limited | Wholesale & retail | 2007 |
| Sheffield One (Hotel Management) Limited | Hospitality | 2018 |
| Sheffield One (Hotel) Limited | Real estate | 2018 |
| Sheffield One (UK) Limited | Real estate | 2018 |
| Shel Lettings Limited | Real estate | 2022 |
| Shire Projects Homes Limited | Real estate | 2025 |
| Shire Projects Ltd | Construction | 2016 |
| Shoreline Turkey Limited | Hospitality | 2017 |
| Simflex Ltd | Professional & scientific | 2022 |
| Simmondley News Ltd | Transport & logistics | 2018 |
| Simmondley Smiles Limited | Health & social care | 2022 |
| Simple Window Solutions Limited | Other services | 2012 |
| Simply Inspirational Ltd | Manufacturing | 2013 |
| Sintered Media Productions Ltd | Manufacturing | 2019 |
| Site Steps Software Ltd | Information & communication | 2026 |
| SJS Monks Ltd | Construction | 2020 |
| SJY Aesthetics Ltd | Health & social care | 2025 |
| SJY Solutions Ltd | Professional & scientific | 2018 |
| SK Vans Limited | Wholesale & retail | 2019 |
| Skinology LAB Limited | Wholesale & retail | 2021 |
| Skupham's Jewellers Limited | Wholesale & retail | 2008 |
| Skye Supply Ltd | Wholesale & retail | 2026 |
| Skye Ward Property & Development Ltd | Real estate | 2020 |
| Skyline Elevated Platforms Ltd | Construction | 2020 |
| Skyrope Ltd | Construction | 2017 |
| SL Contracting Ltd | Construction | 2024 |