| Deane Commerce Ltd | Wholesale & retail | 2023 |
| Debbyinter Ltd | Health & social care | 2015 |
| Debdandav OBA Limited | Wholesale & retail | 2018 |
| Debetur Limited | Administrative & support | 2024 |
| Debont Engineering Ltd | Professional & scientific | 2025 |
| Decho Decoration Material Co., Ltd | Manufacturing | 2021 |
| Decor Tiles & Floors Limited | Construction | 2000 |
| Decorative Events by J&T Ltd | Hospitality | 2025 |
| Dee's Curious Minds Ltd | Education | 2024 |
| Deering Petrophysical Ltd. | Mining & quarrying | 2017 |
| Degame & Co Ltd | Information & communication | 2019 |
| Degiorgio Holdings Limited | Other services | 1990 |
| Delce Limited | Real estate | 2020 |
| Delicate UK Construction Ltd | Construction | 2022 |
| Delite INS Broker Ltd | Financial services | 2023 |
| Delivering Practical Working Solutions Ltd | Professional & scientific | 2014 |
| Delivreel Limited | Transport & logistics | 2019 |
| Delizioso NOI DUE Ltd | Hospitality | 2024 |
| Delta Marine Service Co., Ltd | Manufacturing | 2025 |
| Delta UK Constructions Ltd | Construction | 2022 |
| Demal Services Limited | Health & social care | 2016 |
| Demere Designs Ltd | Construction | 2006 |
| Demure Beauty Ltd | Other services | 2024 |
| Demure Nails Ltd | Other services | 2025 |
| Denbigh Property Investors Ltd | Real estate | 2023 |
| Dene Park Estates Limited | Households | 1990 |
| Deni & LEO Limited | Transport & logistics | 2012 |
| Deniz Beren Ltd | Wholesale & retail | 2016 |
| Denmark Gothi Limited | Wholesale & retail | 2025 |
| Dental Dynamix Imaging Limited | Health & social care | 2011 |
| Dental Nursing Essentials Ltd | Manufacturing | 2025 |
| Denyer Networks Ltd | Information & communication | 2014 |
| Depa-Pasco Services Limited | Information & communication | 2003 |
| Deploy Project Services Limited | Construction | 2023 |
| Deploy Retail Services Limited | Administrative & support | 2012 |
| Dera Care Limited | Health & social care | 2020 |
| Desi Masala House Ltd | Hospitality | 2020 |
| Design Manage Build Ltd | Construction | 2024 |
| Designjam Ltd | Professional & scientific | 2012 |
| Designspot Ltd | Professional & scientific | 2009 |
| Dessy'Sapparel Limited | Manufacturing | 2025 |
| DEV Choice Ltd | Information & communication | 2015 |
| Devoted Care Supported Living Ltd | Administrative & support | 2025 |
| Dewart Investments Ltd | Professional & scientific | 2017 |
| Dexrail Limited | Manufacturing | 2025 |
| Dexreco Limited | Water & waste | 2007 |
| Dexretail Limited | Manufacturing | 2011 |
| Dexterous Technology Professionals Limited | Professional & scientific | 2006 |
| Dezhou Longya Rubber and Plastics Co., Ltd | Extraterritorial | 2018 |
| DF Hong Industry Co., Ltd | Manufacturing | 2023 |
| DFR UK Services Ltd | Wholesale & retail | 2025 |
| DH Interiors Limited | Construction | 2015 |
| DH Treasury Limited | Financial services | 2018 |
| Dhami Group Ltd | Hospitality | 2025 |
| Dhillon Brothers Civil Ltd | Construction | 2024 |
| Dhinsa Healthcare Limited | Mining & quarrying | 2019 |
| Dhruvam Limited | Administrative & support | 2017 |
| Diamei Superabrasives Co., Ltd | Wholesale & retail | 2024 |
| Diamond Aesthetics (Kent) Ltd | Other services | 2023 |
| Diamond Business Solutions Private Limited | Energy | 2024 |
| Diamond Heating and Plumbing Ltd | Construction | 2015 |
| Diamund Ltd | Professional & scientific | 2014 |
| Dian NIL Co., Ltd. | Wholesale & retail | 2023 |
| Diar Ltd | Wholesale & retail | 2026 |
| Diaspora Community Housing CIC | Construction | 2021 |
| Dickens Gates Limited | Construction | 2019 |
| Dickson 12 Limited | Health & social care | 2022 |
| Diets for Dogs Ltd | Professional & scientific | 2018 |
| Digital Camp CIC | Information & communication | 2023 |
| Digital One World Limited | Information & communication | 2023 |
| Digital World Ltd | Information & communication | 2016 |
| Diic Diversity & Inclusion in Construction C.I.C. | Education | 2024 |
| Dinay Catering Ltd | Hospitality | 2025 |
| Dingxin International Development Co., Limited | Extraterritorial | 2016 |
| Direct Air Dryers Limited | Administrative & support | 2005 |
| Direct Commerce Solutions Limited | Wholesale & retail | 2024 |
| Discount Tools and Fixings Limited | Wholesale & retail | 2017 |
| Discovering Wellness Ltd | Health & social care | 2022 |
| Discovery Estates (Kent) Limited | Real estate | 2020 |
| Discovery Investments (Kent) Ltd | Financial services | 2013 |
| Discreet Security by PM Ltd | Administrative & support | 2025 |
| Dishana's Kitchen Ltd | Hospitality | 2020 |
| Distribution Staff Ltd | Administrative & support | 2022 |
| Disturbance Records Ltd | Information & communication | 2025 |
| Dither & Faff Limited | Hospitality | 2017 |
| Divine Windows & Door Services Ltd | Construction | 2023 |
| Dizzy Zebra Limited | Professional & scientific | 2017 |
| DJH Transport Ltd | Administrative & support | 2009 |
| DJS Controls Ltd | Professional & scientific | 2020 |
| DJW Solutions Ltd | Information & communication | 2021 |
| DK Bovis Developments Ltd | Construction | 2015 |
| DKF Homes Ltd | Construction | 2024 |
| Dl-Wills Properties Ltd | Real estate | 2025 |
| DLP Fire Services Ltd | Construction | 2017 |
| DM Electrical Servce Ltd | Construction | 2025 |
| DM1 Construction Ltd | Construction | 2021 |
| Dmab Ltd | Wholesale & retail | 2022 |
| DMD Medway Limited | Transport & logistics | 2019 |
| DMO Data Ltd | Other services | 2014 |
| Dmrs Installations Limited | Construction | 2018 |