| Rosehill Tavern Limited | Hospitality | 2024 |
| Rosemere Assets Ltd | Real estate | 2022 |
| Rosewood Property Management & Development Ltd | Real estate | 2021 |
| Rosey Places Ltd | Households | 2022 |
| Rosie & Bell Ltd | Hospitality | 2024 |
| Rosmic Management Limited | Professional & scientific | 2011 |
| Ross’S Recycled Metals Limited | Wholesale & retail | 2020 |
| Rothbury Home Bakery Limited | Manufacturing | 1999 |
| Route One Couriers and Driver Solutions Ltd | Transport & logistics | 2019 |
| Rove Limited | Education | 2011 |
| Rover With Elizabeth S Limited | Agriculture & fishing | 2025 |
| Rovin Environmental (North East) Limited | Water & waste | 2010 |
| Rovin Services Limited | Professional & scientific | 2015 |
| Rovin Subsea Limited | Construction | 2016 |
| Rowan Specialist Interiors Limited | Construction | 1999 |
| Rowes Garage Limited | Wholesale & retail | 1985 |
| Roxoa Distribution Ltd | Administrative & support | 2021 |
| Roxoa Group Ltd | Professional & scientific | 2014 |
| Royal Northern Sinfonia Limited | Arts & recreation | 2016 |
| Royal Respite Limited | Public administration | 2015 |
| RP & DK Ltd | Hospitality | 2025 |
| Rrdc Ltd | Construction | 2011 |
| RS Aesthetics (NE) Limited | Administrative & support | 2025 |
| RS Doctors Limited | Health & social care | 2015 |
| RS Performance Vehicle Repairs Limited | Wholesale & retail | 2025 |
| RS Publishing Ltd | Information & communication | 2018 |
| RSG Memorabilia Limited | Wholesale & retail | 2013 |
| RSL (North East) Ltd | Administrative & support | 2022 |
| RSL Northwest Ltd | Hospitality | 2020 |
| RSL One Limited | Professional & scientific | 2005 |
| RSL Two Limited | Extraterritorial | 2005 |
| Rspm (NE) Ltd | Other services | 2018 |
| RSS Installations Ltd | Construction | 2025 |
| RT Joinery Contractors Limited | Administrative & support | 2024 |
| RTC Contracting Ltd | Administrative & support | 2021 |
| RTR Technical Limited | Construction | 2020 |
| Rubb Buildings Limited | Manufacturing | 1977 |
| Rubberoofs Ltd | Construction | 2017 |
| Ruby & Oscar Ltd | Wholesale & retail | 2018 |
| Rubyco Limited | Hospitality | 2022 |
| Ruchi Ltd | Hospitality | 2025 |
| Rudchester Limited | Health & social care | 2018 |
| Ruffed Trading Ltd | Health & social care | 2022 |
| Ruiin Ltd | Wholesale & retail | 2026 |
| Rumi Accountants Ltd | Professional & scientific | 2019 |
| Rupz Picks Limited | Wholesale & retail | 2026 |
| RUR Aesthetics Limited | Health & social care | 2021 |
| Ruth Waterhouse Limited | Education | 2007 |
| Rutherford & Clark Electrical Contractors Ltd | Construction | 2022 |
| Rutherford Association Football Club | Arts & recreation | 2008 |
| Rutland Entertainments Limited | Administrative & support | 2023 |
| RW Property Maintenance Ltd | Other services | 2024 |
| Rwco Limited | Professional & scientific | 2005 |
| RWS Financial Planning Limited | Financial services | 2013 |
| Ryan Haulage Ltd | Transport & logistics | 2021 |
| Ryan Reynolds Ltd | Construction | 2023 |
| Ryelore Limited | Information & communication | 2015 |
| S & G Electrical Contractors Ltd | Construction | 2022 |
| S & G Electrical Contractors NE Ltd | Construction | 2023 |
| S & J Electrical Contractors (N.E.) Ltd | Construction | 2015 |
| S & K Hartlepool Limited | Other services | 2010 |
| S & R Builders (North East) Limited | Construction | 2013 |
| S & R Construction Services Limited | Construction | 2002 |
| S & S Leisure Holdings Limited | Hospitality | 2019 |
| S & W Properties Management Ltd | Households | 2018 |
| S & Z Digital Solutions Limited | Information & communication | 2025 |
| S & Z Ventures Ltd | Financial services | 2026 |
| S and D Catering Co Limited | Hospitality | 2004 |
| S and K Newcastle Ltd | Financial services | 2026 |
| S and T Motor Co Ltd | Wholesale & retail | 2020 |
| S Blackburn Painting and Decorating Ltd | Construction | 2025 |
| S D Stanley Ltd | Health & social care | 2009 |
| S Fenwick Ltd | Health & social care | 2022 |
| S Florica Ltd | Health & social care | 2013 |
| S Higgins Solutions Limited | Information & communication | 2023 |
| S Shavit Ltd | Health & social care | 2018 |
| S White Enterprises PMC Limited | Professional & scientific | 2017 |
| S Willey Farming Ltd | Agriculture & fishing | 2024 |
| S Willey Group Ltd | Agriculture & fishing | 2024 |
| S&D Edmundson Plaster & Rendering Ltd | Construction | 2024 |
| S&M BSD Ltd | Construction | 2017 |
| S&N Kaufman Ltd | Real estate | 2016 |
| S&R Foods Ltd | Hospitality | 2022 |
| S&R Retailing Ltd | Wholesale & retail | 2026 |
| S&V Convenience Store Ltd | Wholesale & retail | 2026 |
| S&Z Unity Property Solutions Ltd | Real estate | 2020 |
| S. Mckale & Sons Limited | Construction | 1973 |
| S.A.L. Leisure Limited | Extraterritorial | 1982 |
| S.E Waste Management Ltd | Wholesale & retail | 2017 |
| S.T Pubs Ltd | Hospitality | 2018 |
| S.T.C.S. Ltd | Information & communication | 1988 |
| S.T.M. Estates Limited | Hospitality | 1997 |
| Saachi Food Limited | Hospitality | 2025 |
| Saaz Classics Ltd | Wholesale & retail | 2024 |
| Sabirah Tandoori Ltd | Hospitality | 2024 |
| Sachkeerat Limited | Construction | 2024 |
| Saddle Box Events Ltd | Wholesale & retail | 2025 |
| Sadeh Services Ltd | Education | 2024 |
| Sadie Smulovitch Children's Trust Ltd | Health & social care | 2016 |
| Sadiqaziz Ltd | Information & communication | 2026 |