| RC Lakeside Ltd | Hospitality | 2025 |
| Rccg LSC Camp David Limited | Other services | 2025 |
| RCP Property Group Ltd | Construction | 2025 |
| RCP Property Investments Ltd | Construction | 2025 |
| Rcpay Limited | Financial services | 2019 |
| RE Industries Ltd | Other services | 2018 |
| Re-Sprayit Ltd | Construction | 2026 |
| Reach Further Online Ltd | Professional & scientific | 2019 |
| Reading Solutions UK Limited | Education | 2014 |
| Readwithmills Ltd | Wholesale & retail | 2018 |
| Reagal Events Limited | Arts & recreation | 2024 |
| Real Business Services (NE) Limited | Professional & scientific | 2014 |
| Real REM Limited | Other services | 2022 |
| Real Training Services Limited | Education | 2009 |
| Real YOU Coaching Ltd | Real estate | 2019 |
| Realmstates Limited | Education | 1988 |
| Realprobe Limited | Construction | 1986 |
| Realsafe Technologies Limited | Information & communication | 2012 |
| Realsafe Technology Holdings Limited | Information & communication | 2019 |
| Realstone Developments Ltd | Construction | 2021 |
| REB Katz Ltd | Wholesale & retail | 2026 |
| Rebann Limited | Administrative & support | 2011 |
| Rebel TIP Limited | Information & communication | 2023 |
| Recite ME Limited | Information & communication | 2010 |
| Recm Properties Ltd | Real estate | 2018 |
| Recm Software Ltd | Information & communication | 2018 |
| RECOVERY4LIFE Direct Ltd | Extraterritorial | 2016 |
| Red Chilli Heating Ltd | Professional & scientific | 2018 |
| Red Lion Partners LLP | | 2007 |
| Red Square Newcastle Limited | Arts & recreation | 2003 |
| Red Star Courier Ltd | Transport & logistics | 2018 |
| Red Top Events Limited | Other services | 2016 |
| Redesign Transport Limited | Professional & scientific | 2024 |
| Redfox Coffeeshop Limited | Hospitality | 2024 |
| Redfox Events (North East) Limited | Real estate | 2024 |
| Redfox Garden Centre Limited | Wholesale & retail | 2024 |
| Redfox Gardenworld Limited | Financial services | 2024 |
| Reduxion Engineering Ltd | Information & communication | 2025 |
| Reegal Scaffolding Limited | Construction | 2013 |
| Reel Boss Fish Bar Limited | Hospitality | 2025 |
| Refine Anaesthetic Ltd | Health & social care | 2020 |
| Regal Amusements (North East) Limited | Arts & recreation | 1993 |
| Regal Chox Ltd | Wholesale & retail | 2024 |
| Regal Family Ltd | Extraterritorial | 2011 |
| Regalian Estates Ltd | Real estate | 2020 |
| Regalian Properties Ltd | Real estate | 2020 |
| Regeneration (North East) LLP | | 2007 |
| Regent Funeral Services Limited | Other services | 2017 |
| Rejuvenation Ltd | Wholesale & retail | 2019 |
| Relay Driver Network Ltd | Transport & logistics | 2021 |
| Relda Investments Ltd | Real estate | 2014 |
| Relish Deli Ltd | Wholesale & retail | 2025 |
| Relton Engineering Limited | Professional & scientific | 2015 |
| Remaco Ltd | Construction | 2024 |
| Renaissance Education Group Limited | Financial services | 2024 |
| Renaissance OP Co Limited | Education | 2025 |
| Renaissance Prop Co Limited | Real estate | 2025 |
| Renew Landscapes & Driveways Ltd | Construction | 2021 |
| Renewable Advice Ltd | Professional & scientific | 2008 |
| Renewable Energy Network Limited | Construction | 2019 |
| Renewable Group UK (Holdings) Ltd | Financial services | 2016 |
| Renovating J Builders Ltd | Construction | 2024 |
| Renthall UK Ltd | Real estate | 2010 |
| Rentotal Ltd | Construction | 2022 |
| Renu Group Ltd | Construction | 2019 |
| Renu Studios Ltd | Arts & recreation | 2025 |
| Renwick Accountancy Services Ltd | Professional & scientific | 2010 |
| Renwick Claims Ltd | Administrative & support | 2023 |
| Renwick Stores Ltd | Wholesale & retail | 2017 |
| Renwick Taxi Rentals Ltd | Administrative & support | 2025 |
| Repoint N Limited | Construction | 2025 |
| Repoint North Limited | Construction | 2026 |
| Resilience North East Limited | Health & social care | 2016 |
| Resourceroom-Ne Limited | Education | 2025 |
| Restaurant Design Associates Ltd | Professional & scientific | 2007 |
| Restaurant Kitchen Ltd | Manufacturing | 2016 |
| Restoravyn Limited | Wholesale & retail | 2026 |
| Retime Ltd | Wholesale & retail | 2026 |
| Retirement Bridge Group Holdings Limited | Professional & scientific | 2015 |
| Retirement Bridge Group Limited | Professional & scientific | 2015 |
| Retirement Bridge Home Reversions LP | | 2006 |
| Retirement Bridge Housing Limited | Real estate | 2006 |
| Retirement Bridge Limited | Real estate | 2005 |
| Retirement Bridge Management Limited | Real estate | 2005 |
| Retirement Housing NO. 1 (2007) Limited | Real estate | 2007 |
| Retrofit Compliance Group Ltd | Professional & scientific | 2026 |
| Reuvolt Electricals Limited | Construction | 2023 |
| Revach Ltd | Real estate | 2016 |
| Reve Salon Ltd | Other services | 2020 |
| Reversions Financing (NO.1) 2011 Limited | Administrative & support | 2011 |
| Reversions Financing Limited | Administrative & support | 2011 |
| Revolution Marketing UK Ltd | Professional & scientific | 2003 |
| REW Building Services (NE) Ltd | Construction | 2013 |
| Rezaie Group Ltd | Information & communication | 2019 |
| Rfit-Uk Ltd | Administrative & support | 2024 |
| RG & RB Associates Limited | Professional & scientific | 2024 |
| RG Tees Valley Limited | Professional & scientific | 2020 |
| Rgif. Access Solutions Limited | Construction | 2022 |
| RH & BH Logistics Limited | Transport & logistics | 2019 |
| RHJ Managed Services Limited | Real estate | 2024 |