| QP Jewellers LLP | | 2010 |
| Quadent Ltd | Wholesale & retail | 2015 |
| Qualitek Occupational Health Limited | Health & social care | 2017 |
| Qualitek Safety Limited | Professional & scientific | 2012 |
| Quality Care Health Ltd | Health & social care | 2023 |
| Quality Chippy (NE) Ltd | Hospitality | 2024 |
| Quality Landscape Services (NE) Limited | Administrative & support | 2022 |
| Quality Trade Windows (Gateshead) Limited | Manufacturing | 2009 |
| Quantum Hipno Energy Ltd | Health & social care | 2026 |
| Quantum-Jigsaw Consulting Ltd | Professional & scientific | 2014 |
| Quantus Window Films UK Ltd | Construction | 2009 |
| Quay Point Properties Ltd | Real estate | 2022 |
| Quayside Court Management Company Limited | Households | 1985 |
| Quayside News 5 Limited | Wholesale & retail | 2014 |
| Quayside News 7 Limited | Wholesale & retail | 2017 |
| Quayside Sandhill Limited | Real estate | 2024 |
| Quayside Therapy Limited | Other services | 2026 |
| Queensberry Design (Geotechnical & Environmental) Limited | Professional & scientific | 2025 |
| Queensberry Design (Yorkshire) Limited | Professional & scientific | 2024 |
| Queensberry Design Limited | Professional & scientific | 2002 |
| Queenscliff Associates Ltd | Administrative & support | 2025 |
| Queensgate Leisure (Bradford) Limited | Extraterritorial | 2019 |
| Quinn Management Services (NE) Limited | Construction | 2016 |
| QW Security Limited | Administrative & support | 2006 |
| R & a Accountancy Services Limited | Professional & scientific | 2013 |
| R & B Property Services NE Ltd | Construction | 2023 |
| R & D Patterson Limited | Wholesale & retail | 2002 |
| R & K Hartlepool Limited | Wholesale & retail | 2010 |
| R & K Teesside Locums Limited | Health & social care | 2012 |
| R & M GAS Services Limited | Construction | 2026 |
| R & R Petroleum UK Ltd | Wholesale & retail | 2024 |
| R & S Bathla Ltd | Hospitality | 2025 |
| R & S Enterprise PVT Limited | Real estate | 2015 |
| R a E Scaffolding Ltd | Construction | 2025 |
| R a S Properties (North East) Ltd | Construction | 2018 |
| R a Wood Pallet’S Recycling Ltd | Manufacturing | 2023 |
| R B Thompson Property Solutions Ltd | Construction | 2024 |
| R G Young Pharmacy Ltd | Wholesale & retail | 2005 |
| R H Orange Properties Ltd | Real estate | 2021 |
| R J Blackson Ltd | Administrative & support | 2018 |
| R Omer Healthcare Limited | Health & social care | 2022 |
| R Tarr Properties Limited | Real estate | 2021 |
| R Walker & Co (North East) Limited | Professional & scientific | 2013 |
| R Walker & Co Limited | Professional & scientific | 2003 |
| R&J Hill Properties Ltd | Real estate | 2022 |
| R&P Yadav Ltd | Hospitality | 2024 |
| R&S (NE) UK Properties Ltd | Real estate | 2021 |
| R. Dinning Limited | Wholesale & retail | 1963 |
| R. Parker (Wall & Floor Tiling Contractors) Limited | Construction | 1975 |
| R.A.Star Ltd | Hospitality | 2019 |
| R.A.W. Potatoes Ltd | Administrative & support | 2005 |
| R.A.Y Plastering Contractor Ltd | Construction | 2022 |
| R.D. Franks Limited | Transport & logistics | 1937 |
| R.H. Orange & SON Limited | Wholesale & retail | 2001 |
| R.P. Marketing Limited | Administrative & support | 2016 |
| R2MC Limited | Financial services | 2011 |
| R4CAD Ltd | Administrative & support | 2009 |
| R999 Limited | Information & communication | 2015 |
| Raccoon Trading Limited | Wholesale & retail | 2012 |
| Radecal Signs and Graphics Ltd | Manufacturing | 2017 |
| Radentis Ltd | Health & social care | 2021 |
| Radstone Construction Ltd | Construction | 2022 |
| Raffles Enterprises & Services Ltd | Other services | 2019 |
| Raffo Holdings Ltd | Real estate | 2021 |
| Ragip Investments Ltd | Real estate | 2021 |
| Ragip Ltd | Health & social care | 2017 |
| Ragnarok Investments Limited | Construction | 2016 |
| RAI Academy Limited | Education | 2022 |
| Railway RAY Ltd | Construction | 2023 |
| Rainbow Cantonese Restaurant Limited | Hospitality | 2012 |
| Raise Your Voice (Music) Ltd | Information & communication | 2026 |
| RAISE2SHINE Ltd | Administrative & support | 2021 |
| Rajeev & SON Limited | Real estate | 2021 |
| RAL Limited | Arts & recreation | 1985 |
| RAM Projects Ltd | Health & social care | 2018 |
| Rameez Riaz Ltd | Wholesale & retail | 2026 |
| Ramirez Ltd | Health & social care | 2025 |
| Ramo Estates Ltd | Real estate | 2025 |
| Ramoshop Ltd | Wholesale & retail | 2023 |
| Ranay Ltd | Real estate | 2022 |
| Rangan MS Limited | Health & social care | 2002 |
| Rangan Property Services LLP | | 2007 |
| Rapid Fluidics Limited | Professional & scientific | 2020 |
| Rapid Tooling Group Limited | Wholesale & retail | 2020 |
| Rapid Tooling Solutions Limited | Wholesale & retail | 2015 |
| Rapid Water Courses Limited | Construction | 2011 |
| Rapport | | 1998 |
| Rasheed Trading Ltd | Wholesale & retail | 2019 |
| Ratstone Properties Limited | Real estate | 2023 |
| Ravech Ltd | Real estate | 2016 |
| Ravenside Ltd | Real estate | 2014 |
| Ravenside Trust | Real estate | 2022 |
| Ravensworth Golf Club,Limited(The) | Arts & recreation | 1912 |
| Ravensworth Home Entertainment and Security Solutions Limited | Administrative & support | 2016 |
| Ravensworth Mews Management Company Limited | Extraterritorial | 2007 |
| RAY & Sun Property Services Ltd | Administrative & support | 2026 |
| Razor's Smart Electrical Ltd | Construction | 2022 |
| RB Properties (North East) Limited | Real estate | 2017 |
| RBA Residential Ltd | Real estate | 2026 |
| Rbmco Ltd | Professional & scientific | 2024 |