| European Pipeline Engineering (Southern) Limited | Manufacturing | 2003 |
| European Pipeline Group Limited | Construction | 1993 |
| European Trading Online Ltd | Wholesale & retail | 2014 |
| Eurotech Environmental (Holdings) Limited | Professional & scientific | 2003 |
| Eurotech Environmental Limited | Water & waste | 1991 |
| Eurotech Environmental Tanker Services Ltd | Water & waste | 2012 |
| Eurotech Tanker Services Ltd | Water & waste | 2012 |
| Eurotech Waste Treatment Limited | Water & waste | 2016 |
| EV Sports Ltd | Extraterritorial | 2018 |
| Evans Computer Consultancy Limited | Information & communication | 2002 |
| Evantech Quality Services Ltd | Professional & scientific | 2024 |
| Evas Estate Limited | Real estate | 2020 |
| Evedent Limited | Health & social care | 2019 |
| Evedent Property Limited | Real estate | 2025 |
| Event Space Cleaning Ltd | Administrative & support | 2025 |
| Everest & Snow Limited | Wholesale & retail | 2024 |
| Everhaven Developments Ltd | Real estate | 2026 |
| Everhaven Properties Ltd | Real estate | 2026 |
| Everrend Ltd | Construction | 2012 |
| Everyone CAN Have One Ltd | Health & social care | 2025 |
| Everypaws Gentle Goodbyes Limited | Professional & scientific | 2025 |
| Evesham Specsavers Hearcare Limited | Wholesale & retail | 2026 |
| Evesham Specsavers Limited | Wholesale & retail | 1995 |
| Evesham Visionplus Limited | Wholesale & retail | 1995 |
| Evolution Autocentre Ltd | Administrative & support | 2017 |
| Evolution Autotrader Ltd | Wholesale & retail | 2020 |
| Evolution Hire Group Ltd | Administrative & support | 2026 |
| Evolv Electrical Ltd | Professional & scientific | 2025 |
| Evolve Accounting Services Ltd | Professional & scientific | 2014 |
| Evolve Business Limited | Wholesale & retail | 2017 |
| Evolve Club Limited | Information & communication | 2025 |
| Evolve With Adelle Ltd | Professional & scientific | 2026 |
| Evolving Projects Ltd | Professional & scientific | 2018 |
| Evory Properties Ltd | Real estate | 2024 |
| Ewan Sutherland Carpentry & Joinery Limited | Construction | 2019 |
| Ewatersports Ltd | Wholesale & retail | 2023 |
| Excalibur Communications GB Limited | Information & communication | 2000 |
| Excalibur Communications Group Limited | Financial services | 2018 |
| Exceed Property Services Ltd | Construction | 2023 |
| Excel GAS Limited | Construction | 2017 |
| EXCEL4UK Care Solutions Limited | Health & social care | 2020 |
| Excelia Investments Limited | Other services | 2015 |
| Exceptionalcx Limited | Professional & scientific | 2019 |
| Exclusive + Limited | Financial services | 2023 |
| Exclusive Garages UK Limited | Manufacturing | 2020 |
| Exclusive Pro Limited | Construction | 2024 |
| EXE Projects Limited | Construction | 2016 |
| Exeter Domi Audiology Specsavers Limited | Wholesale & retail | 2023 |
| Exeter Domiciliary Specsavers Limited | Wholesale & retail | 2022 |
| Exeter Specsavers Hearcare Limited | Wholesale & retail | 2006 |
| Exeter Specsavers Limited | Wholesale & retail | 1985 |
| Exeter Visionplus Limited | Wholesale & retail | 1993 |
| Exmouth Specsavers Limited | Wholesale & retail | 2013 |
| Exo-Cubic Solutions Ltd. | Professional & scientific | 2014 |
| Exocyte Limited | Mining & quarrying | 2006 |
| Exonar Limited | Information & communication | 2007 |
| EXP D & P Ltd | Wholesale & retail | 2020 |
| Expert Building Trades Ltd | Information & communication | 2016 |
| Expert Local Management Limited | Professional & scientific | 2017 |
| Expert Manufacturers Ltd | Information & communication | 2016 |
| Expert Manufacturing Limited | Other services | 2017 |
| Expert Psychological Associates Ltd | Health & social care | 2021 |
| Expertech Computing Ltd | Information & communication | 1997 |
| Explorejoy Limited | Wholesale & retail | 2024 |
| Expression for Growth Limited | Professional & scientific | 2000 |
| Exquisite Precision Engineering Ltd | Manufacturing | 2019 |
| Exsel Pumps Limited | Construction | 1997 |
| EXTENSION67 Limited | Information & communication | 2014 |
| Extrateq Limited | Energy | 2018 |
| EYE SPY Systems Limited | Administrative & support | 2026 |
| Eyecom Limited | Financial services | 2023 |
| Eyes on Community Limited | Information & communication | 2023 |
| Ezecurtains Ltd | Other services | 2021 |
| Ezyeducation Ltd | Education | 2013 |
| Ezza Logistics Ltd | Transport & logistics | 2018 |
| F & S Projects Limited | Construction | 2018 |
| F D C International Limited | Manufacturing | 1996 |
| F S H Driving School Ltd | Education | 2018 |
| F&S Autos Ltd | Wholesale & retail | 2026 |
| F.A.B Publishing Ltd | Information & communication | 2023 |
| F.T.E. Group Limited | Financial services | 2018 |
| F.T.E. Group Trustees Limited | Professional & scientific | 2018 |
| F1 Hair and Beauty Ltd | Other services | 2007 |
| Fabian Feltham Ltd | Professional & scientific | 2019 |
| Facers Ltd | Professional & scientific | 2019 |
| Facile Ltd | Real estate | 2024 |
| Fair Rents (Pompey) Limited | Real estate | 2022 |
| Fairchild Financial Ltd | Real estate | 2018 |
| Fairchise Ltd | Information & communication | 2025 |
| Fairdale Limited | Households | 1988 |
| Fairfield Park Specsavers Limited | Wholesale & retail | 2022 |
| Fairhead Electrical Limited | Construction | 2020 |
| Fairness Group Ltd | Information & communication | 2019 |
| Fairview Yacht Charter Limited | Arts & recreation | 2017 |
| Faithful Friends Mobile VET Ltd | Professional & scientific | 2024 |
| Fakenham Specsavers Limited | Wholesale & retail | 2005 |
| Fakenham Visionplus Limited | Wholesale & retail | 2005 |
| Falcon Estates Portsmouth Ltd | Real estate | 2019 |
| Falcon Survey and Engineering Solution Ltd | Construction | 2020 |
| Falcon UK Jvco Limited | Real estate | 2021 |