| Castle Cctv Limited | Information & communication | 2008 |
| Cater Bearwood Limited | Information & communication | 2007 |
| Caudrelier Limited | Administrative & support | 2017 |
| Cauleston House RTM Company Limited | Administrative & support | 2007 |
| Caust Creations Ltd. | Professional & scientific | 2016 |
| Cazmaz Limited | Construction | 2013 |
| Cbgb Ltd | Professional & scientific | 2015 |
| CDH Real Estate Ltd | Real estate | 2025 |
| CDS Diesels Ltd | Manufacturing | 2014 |
| Cellix Limited | Professional & scientific | 1992 |
| Centre Stone Construction Ltd | Professional & scientific | 2023 |
| CFR Safety & Environmental Services Ltd | Professional & scientific | 2019 |
| Charlie Lovell Limited | Professional & scientific | 2025 |
| Charlotte Rowley Hair Education Ltd | Education | 2024 |
| Charlotte Rowley Hair Ltd | Other services | 2024 |
| Charlotte Tucker Aesthetics Limited | Other services | 2025 |
| Chelston Nurseries and Plant Centre Limited | Extraterritorial | 2024 |
| Cheriswood UK Limited | Extraterritorial | 2022 |
| Chiffle Ltd | Wholesale & retail | 2022 |
| Chris Sunman Limited | Professional & scientific | 2003 |
| Church Road Management (Exeter) Limited | Households | 1996 |
| City to Sea Property Ltd | Households | 2025 |
| Civik Limited | Information & communication | 2025 |
| Civil Engineering & Client Services Ltd | Administrative & support | 2017 |
| CJB Wholesale Fruit and VEG Ltd | Wholesale & retail | 2016 |
| Claire Veness Legal Limited | Professional & scientific | 2021 |
| Clarence IT Consulting Limited | Information & communication | 2012 |
| Classic (South West) Ltd | Wholesale & retail | 2017 |
| Classic Italia Ltd | Hospitality | 2025 |
| Claw and Order Ltd | Agriculture & fishing | 2026 |
| Claymore Compliance Consultants Ltd | Administrative & support | 2014 |
| Clean AS a Whistle Ltd | Administrative & support | 2022 |
| Cleaner Carpets (Devon) Limited | Administrative & support | 2021 |
| Clearwater Diving Ltd | Agriculture & fishing | 2019 |
| Cloud 9 Drones Ltd | Professional & scientific | 2026 |
| Clumberstone International Ltd | Financial services | 2026 |
| Clyde Lodge Management Company (Exmouth) Limited | Households | 2003 |
| Cmvi Limited | Professional & scientific | 2002 |
| Co Adventurers Limited | Education | 2020 |
| Coastal Childcare (SW) Ltd | Financial services | 2024 |
| Coastal Lounge Group Limited | Hospitality | 2025 |
| Cobra IT Ltd | Information & communication | 2016 |
| Cockman Builders SW Ltd | Construction | 2020 |
| Code Zero Yachts Ltd. | Administrative & support | 2022 |
| Collectables and ETC Limited | Wholesale & retail | 2022 |
| College Four RTM Company Ltd | Households | 2019 |
| Comfort Heating & Stoves Ltd | Wholesale & retail | 2012 |
| Communication Insights Ltd | Professional & scientific | 2023 |
| Comxm Limited | Professional & scientific | 2023 |
| Concept Graphics Limited | Administrative & support | 2001 |
| Conibere Holdings Limited | Real estate | 2024 |
| Connected Procurement Ltd | Professional & scientific | 2020 |
| Connock Properties Limited | Construction | 2005 |
| Construct PHR Limited | Construction | 2024 |
| Construction Partners Ltd | Construction | 2014 |
| Constructiv Growth Management Ltd | Professional & scientific | 2025 |
| Consultafrica 232 Limited | Transport & logistics | 2006 |
| Container Supplies Ltd | Transport & logistics | 2014 |
| Content Studios Group Limited | Information & communication | 2019 |
| Control Descent Limited | Construction | 2015 |
| Corbeau Noir Limited | Other services | 2021 |
| Core Fitness Performance Education Academy Limited | Education | 2023 |
| Cork Pages CRU Ltd | Wholesale & retail | 2023 |
| Corver Limited | Construction | 1999 |
| Cotilda Home Care Services Limited | Health & social care | 2025 |
| Cottage Commercial Limited | Real estate | 1996 |
| Couper Street Type Company Limited | Information & communication | 2018 |
| Courier 24/7 Devon & Cornwall Ltd | Transport & logistics | 2020 |
| Courtlands Mansion Limited | Construction | 2000 |
| Cove Pubs Limited | Hospitality | 2025 |
| Crandev Limited | Construction | 2014 |
| Cranford Beehive Management Limited | Households | 2014 |
| Cranford Court (Exmouth) Management Company Limited | Households | 1998 |
| Creative Enabling Limited | Health & social care | 2023 |
| Creative Paper Products Limited | Manufacturing | 1992 |
| Creech Developments Ltd | Real estate | 2023 |
| Creech Properties Limited | Construction | 2026 |
| Cryo Home Ltd | Extraterritorial | 2024 |
| Ctfr Holdings Ltd | Real estate | 2017 |
| Curry Cottage ( Exmouth ) Limited | Hospitality | 2022 |
| Curveconsult Ltd | Professional & scientific | 2019 |
| D & D Solutions Ltd | Construction | 2018 |
| D M Imperial Limited | Hospitality | 2017 |
| D W Oliver Frcs Limited | Health & social care | 2010 |
| D&P Bricklaying Specialists Limited | Construction | 2023 |
| D&S Hall Ltd | Health & social care | 2021 |
| D8 ARY Limited | Real estate | 2025 |
| Dalf Consultancy Limited | Information & communication | 2007 |
| Danes House Management Company (Exeter) Limited | Real estate | 1998 |
| Daneswood Web Services Limited | Information & communication | 2021 |
| Daniel J Jordan Ltd | Construction | 2023 |
| Darren Everett Pro Golf Limited | Wholesale & retail | 2015 |
| Dartmoor Coins Limited | Wholesale & retail | 2026 |
| Dartmoor Joinery Limited | Construction | 2018 |
| Darwood Developments Ltd | Construction | 2025 |
| Dastan CUT Limited | Other services | 2024 |
| Datafiltr Ltd | Wholesale & retail | 2014 |
| Davis Fluid Consultants Limited | Construction | 2018 |
| Dawlish Sands Caravans Ltd | Wholesale & retail | 2015 |
| DBL Contractors Limited | Construction | 2025 |