| Squabmoor Farm Limited | Agriculture & fishing | 2010 |
| Squire Hyde Limited | Professional & scientific | 2003 |
| SR Coatings Ltd | Construction | 2024 |
| ST Oakes Management Company Limited | Real estate | 2011 |
| ST Olans Development Ltd | Construction | 2014 |
| ST Olans Property Limited | Construction | 2014 |
| ST Wilfrid's School Devon Limited | Education | 2022 |
| ST. James Court 1996 (Plymouth) Limited | Households | 1996 |
| ST. John's Mews Management (Exmouth) Limited | Real estate | 1997 |
| ST. Olans Management Company Ltd | Households | 2016 |
| ST. Vincents Management Company (Exmouth) Limited | Households | 1988 |
| Stag Inns (Exmouth) Limited | Hospitality | 1989 |
| Star Fryer Limited | Hospitality | 2017 |
| Star Student Limited | Administrative & support | 2012 |
| Starinvest Ltd | Transport & logistics | 2022 |
| Stayture Ltd | Real estate | 2024 |
| Stealth Holdings Group Ltd | Financial services | 2026 |
| Steel Services (Southern) Ltd | Professional & scientific | 2026 |
| Stoke Gabriel Developments Limited | Construction | 2026 |
| Stonedale Management and Investments Ltd | Professional & scientific | 2016 |
| Stoneyoak Construction Limited | Real estate | 2015 |
| Straight Marketing Limited | Professional & scientific | 2012 |
| Strand Court Association Limited | Households | 1963 |
| Strategic Inclusivity Ltd | Extraterritorial | 2024 |
| Strawberry TIN Property Ltd | Real estate | 2024 |
| Streetline Property Investments Ltd | Real estate | 2024 |
| Streetline Property Trading Ltd | Real estate | 2024 |
| Structure Homes SL Ltd | Construction | 2024 |
| Style & Design Limited | Wholesale & retail | 2020 |
| Sun Lodge NO.106 Masonic Hall Limited | Extraterritorial | 2015 |
| Sunhill Pre-School and Nursery Ltd | Health & social care | 2025 |
| Sunnymead Flat Management Limited | Hospitality | 2016 |
| Sunshine Pre-School Exmouth Limited | Education | 2014 |
| Super Eagle Ltd | Financial services | 2021 |
| Support Courier UK Ltd | Transport & logistics | 2022 |
| Support for Success Limited | Construction | 2024 |
| Sure Paraplanning Ltd | Financial services | 2022 |
| Surfing Computers Limited | Other services | 2017 |
| Sustainhourability Ltd | Professional & scientific | 2021 |
| Sutton Medical Ltd | Health & social care | 2022 |
| SW Vending Limited | Wholesale & retail | 2024 |
| Swantech Logistics Limited | Professional & scientific | 2007 |
| Swifill Limited | Construction | 2024 |
| Swifix Limited | Construction | 2015 |
| Switchgear Storage Limited | Transport & logistics | 2024 |
| Sylvan Court RTM Company Limited | Administrative & support | 2009 |
| T B N Electrical Ltd | Construction | 2017 |
| T R S Bespoke Interiors Ltd | Manufacturing | 2022 |
| T1 Properties Ltd | Real estate | 2025 |
| T4M Coaching Ltd | Professional & scientific | 2023 |
| Tailor-Made Plates Ltd | Manufacturing | 2025 |
| Tailored Care and Nurture Ltd | Administrative & support | 2021 |
| Tanaka Spaces Limited | Real estate | 2025 |
| Tandoori Nights EX Limited | Hospitality | 2024 |
| Tania's Tots Under Fives Limited | Health & social care | 2013 |
| Tarnhelm Opera CIC | Arts & recreation | 2019 |
| Taunton Counselling Service | Health & social care | 2010 |
| Taylor H Limited | Construction | 2015 |
| Taylor Hardman Ltd | Construction | 2022 |
| Taylor’D Nails Ltd | Other services | 2022 |
| Teach-Ed Recruitment Ltd | Administrative & support | 2026 |
| Techcompass Group Ltd | Information & communication | 2025 |
| Teddies Garden Ltd | Arts & recreation | 2021 |
| Teesra House RTM Company Limited | Households | 2026 |
| Temor Limited | Households | 2005 |
| Templetown (Exmouth) Limited | Households | 2010 |
| Templetown Properties Limited | Households | 2003 |
| Tenancy Legal Limited | Information & communication | 2023 |
| Tender Victory Ltd | Professional & scientific | 2014 |
| Terraformer Consulting Limited | Professional & scientific | 2024 |
| TGS Courier Ltd | Transport & logistics | 2024 |
| TH Scrap Metal Collection Limited | Other services | 2017 |
| That Bloke WHO Does Ltd | Construction | 2024 |
| THE Avocet Learning Trust | Education | 2013 |
| THE Barefoot Bandit LLP | | 2025 |
| THE Barn Exmouth Ltd | Real estate | 2015 |
| THE Barrel House Ballroom CIC | Arts & recreation | 2021 |
| THE Bridal House of Cornwall Limited | Wholesale & retail | 2013 |
| THE Chase Property Management Limited | Households | 2018 |
| THE Commando PTI Ltd | Education | 2025 |
| THE Complete Building Regs Service Limited | Construction | 2013 |
| THE Connected Development Project CIC | Professional & scientific | 2019 |
| THE Creation Station Limited | Education | 2004 |
| THE Devon Centre for Birth CIC | Education | 2026 |
| THE Digital Accessorie Market Ltd | Wholesale & retail | 2022 |
| THE Empower School Ltd | Education | 2023 |
| THE Eurotech Group PLC | Manufacturing | 1991 |
| THE EYE Expert Limited | Health & social care | 2012 |
| THE Fish Shed Devon Limited | Wholesale & retail | 2021 |
| THE Flowstate Collective Limited | Manufacturing | 2026 |
| THE Golf Marketing Ltd | Professional & scientific | 2026 |
| THE Green Property Company (SW) Limited | Construction | 2023 |
| THE Green Window Company (SW) Limited | Construction | 2009 |
| THE Healthcare Leadership Academy CIC | Education | 2017 |
| THE Infinity Electrical Group Ltd | Professional & scientific | 2024 |
| THE Italian Store Exmouth Ltd | Wholesale & retail | 2022 |
| THE JAM Interiors Group Limited | Wholesale & retail | 2010 |
| THE Knock Through GUY Limited | Extraterritorial | 2026 |
| THE Laser Clinic Exmouth Ltd | Health & social care | 2019 |
| THE Letting Centre Limited | Information & communication | 1992 |