| Ecom Studios Limited | Information & communication | 2011 |
| ECOM6 Limited | Information & communication | 2015 |
| Ecommerce Studios Ltd | Information & communication | 2020 |
| Econoweld Ltd | Financial services | 2025 |
| Ecosmart Industry Limited | Manufacturing | 2024 |
| Ecotech Glazing Ltd | Construction | 2025 |
| ECP Manco Limited | Real estate | 1998 |
| ECU Dynamics Ltd | Wholesale & retail | 2020 |
| Eculture Limited | Professional & scientific | 2010 |
| Ecwfc Limited | Arts & recreation | 2024 |
| ED Kowalski Removals Ltd | Transport & logistics | 2020 |
| EDA Works Ltd | Information & communication | 2017 |
| Edenwell Developments Ltd | Real estate | 2014 |
| Edge Economic Consulting Ltd | Professional & scientific | 2023 |
| Edginswell Business Park Management Limited | Real estate | 2010 |
| Ediz Limited | Wholesale & retail | 2014 |
| EDM Site Engineering Ltd | Construction | 2026 |
| EDP Environmental (Southern) Ltd | Professional & scientific | 2020 |
| Edson Tiger Limited | Administrative & support | 2004 |
| Edtesa Limited | Extraterritorial | 2015 |
| Eduard Florea Motors Ltd | Wholesale & retail | 2023 |
| Educate School Services Ltd | Administrative & support | 2010 |
| Edventure Abroad Limited | Education | 2023 |
| Edward Hitchen Associates Limited | Wholesale & retail | 1997 |
| Edwards Flowers Ltd | Wholesale & retail | 2022 |
| EDX Solutions Ltd | Transport & logistics | 2020 |
| EEB17 Limited | Energy | 2017 |
| EEB31 Limited | Energy | 2019 |
| EEE Recica Ltd | Real estate | 2025 |
| Efes (SW) Ltd | Hospitality | 2026 |
| Efes Group of Company Ltd | Wholesale & retail | 2025 |
| Effective Security SW Ltd | Administrative & support | 2025 |
| Efficient Brewing Ltd | Information & communication | 2025 |
| Egerton-Dowling Limited | Real estate | 1955 |
| EGF Group Ltd | Construction | 2013 |
| Egghead Property Ltd | Real estate | 2023 |
| Egmanton Solar Park Limited | Energy | 2013 |
| EIC Investment Properties Limited | Real estate | 2021 |
| Eight Technology Limited | Information & communication | 2003 |
| EIGHT8 Ltd | Information & communication | 2024 |
| Eighteen GCR Ltd | Wholesale & retail | 2018 |
| Eirclear Customs Limited | Transport & logistics | 2020 |
| EIS Properties Limited | Real estate | 2018 |
| EJ Bridal & Hair Extensions Ltd | Other services | 2025 |
| EJ Hill Ltd | Real estate | 2020 |
| Ejbc UK Holdings Limited | Real estate | 2020 |
| Ejfp Planning Limited | Construction | 2011 |
| EJL Hairdressing Limited | Other services | 2025 |
| Ejwa Limited | Real estate | 2014 |
| EL Machino's Ltd | Administrative & support | 2019 |
| Elazig 23 Ltd | Hospitality | 2026 |
| Elbury Barn Limited | Real estate | 2023 |
| Elderflower Coaching Ltd | Administrative & support | 2019 |
| Eleanor Tallowin Limited | Professional & scientific | 2017 |
| Electracheck Services Ltd | Manufacturing | 2026 |
| Electrical Display Solutions Limited | Construction | 2016 |
| Electrical Engineering Enterprises Ltd | Information & communication | 2023 |
| Electrical Safe Products Ltd | Wholesale & retail | 1997 |
| Electrical Testing Surveyors Holdings Limited | Financial services | 2019 |
| Electrical Testing Surveyors Limited | Manufacturing | 2001 |
| Electricc Ltd | Construction | 2022 |
| Electricity Storage Network Limited | Energy | 2011 |
| Electro-Diesel (RCJ) Ltd. | Wholesale & retail | 1995 |
| Electrodeal Ltd | Wholesale & retail | 2023 |
| Element Hospitality Limited | Hospitality | 2026 |
| Elemental Group Limited | Hospitality | 2023 |
| Elemental Health and Care Ltd | Professional & scientific | 2024 |
| Elements Festival Ltd | Administrative & support | 2023 |
| Elements South West Limited | Construction | 2014 |
| Eleos Coalitions Ltd | Manufacturing | 2022 |
| Elevate Detailing UK Ltd | Wholesale & retail | 2026 |
| Elevate Market Intelligence Limited | Information & communication | 2025 |
| Elevate South West Ltd | Construction | 2024 |
| Elevate Venue Consulting Ltd | Professional & scientific | 2025 |
| Elevatia Consulting Ltd | Professional & scientific | 2025 |
| Elford Management Company Limited | Households | 2011 |
| Elijah Webb Company Ltd | Manufacturing | 2021 |
| Elisei Ltd | Health & social care | 2017 |
| Elite 710 Ltd | Wholesale & retail | 2020 |
| Elite Blinds & Tracks Limited | Manufacturing | 2002 |
| Elite Bricklaying Ltd | Construction | 2023 |
| Elite Cleaning (South Devon) Limited | Administrative & support | 2014 |
| Elite Construction Piling & Underpinning Ltd | Construction | 2019 |
| Elite Electrical Devon Ltd | Construction | 2022 |
| Elite GAS Ltd | Construction | 2023 |
| Elite Lifestyle Medicine Ltd | Health & social care | 2023 |
| Elite Optical Distribution Limited | Administrative & support | 2018 |
| Elite Pain & Performance Limited | Health & social care | 2024 |
| Elite Partners Ltd | Information & communication | 2022 |
| Elite Resin Flooring Ltd | Administrative & support | 2023 |
| Elite Roofing Group Limited | Administrative & support | 2024 |
| Elite Spray Foam Instruction Removal Ltd | Construction | 2025 |
| Elite Spray Foam Insulation Removal Ltd | Construction | 2025 |
| Elite Vehicle Fleet Managment Limited | Other services | 2016 |
| Elix Limited | Information & communication | 2005 |
| ELIZ-17 Ltd | Hospitality | 2022 |
| Elizabeth ANN of Exeter Limited | Wholesale & retail | 2011 |
| Elkan Court Freehold Limited | Real estate | 2014 |
| Ella Romanos Limited | Information & communication | 2014 |
| Ella-Mae Rayner Limited | Other services | 2021 |