| Elliott Home Care Limited | Health & social care | 2015 |
| ELM Villa & Madeley Practice Limited | Health & social care | 2008 |
| ELM Villa Holdings Limited | Financial services | 2022 |
| Elmet DC Limited | Health & social care | 2022 |
| Elna Property Management Limited | Real estate | 2013 |
| Elodie Estates Limited | Real estate | 2020 |
| Elysiian Enterprise Ltd | Manufacturing | 2026 |
| EMG Management Ltd | Other services | 2024 |
| Emote Limited | Professional & scientific | 2009 |
| Empeiria Training Limited | Health & social care | 2021 |
| Empowered 2 Change Ltd | Administrative & support | 2025 |
| Empowered Eats Ltd | Hospitality | 2024 |
| EMS Mobiles Ltd | Wholesale & retail | 2023 |
| Emva Financial Ltd | Professional & scientific | 2016 |
| Emvy Properties Ltd | Real estate | 2026 |
| Endeavour Referrals Ltd | Financial services | 2022 |
| Endo Felicitas Limited | Health & social care | 2011 |
| Endsleigh Estates Limited | Real estate | 2025 |
| Energy Innovation Centre Limited | Professional & scientific | 2011 |
| Energy Score Limited | Administrative & support | 2018 |
| Engine Clinic Ltd | Wholesale & retail | 2018 |
| Ensign Holdings Limited | Financial services | 2019 |
| Ensign Site Services Limited | Manufacturing | 2003 |
| Entep Properties Limited | Real estate | 1983 |
| Enzo Brown Limited | Wholesale & retail | 2018 |
| EOC Global Limited | Manufacturing | 2016 |
| EOE Dental Initiative Limited | Health & social care | 2024 |
| EP Bargain Ltd | Wholesale & retail | 2024 |
| EPC Development Ltd | Construction | 2018 |
| Epic Vibes International Ltd | Wholesale & retail | 2024 |
| Eppcon Ltd | Professional & scientific | 2019 |
| EPS Bargain Ltd | Wholesale & retail | 2025 |
| EPS Dent Ltd | Health & social care | 2025 |
| ERD Mobile Auto Repair & Electrical Sysytem Limited | Wholesale & retail | 2021 |
| Eretail IT Supplies Ltd | Wholesale & retail | 2022 |
| Eric Cottrell Ltd | Transport & logistics | 2015 |
| Ernest Griffiths Consulting Engineers LLP | | 2020 |
| Erozone Limited | Wholesale & retail | 2005 |
| ESE Rendering Solutions Ltd | Construction | 2015 |
| ESL Fuels Limited | Manufacturing | 2000 |
| Essar Midlands Limited | Manufacturing | 2018 |
| Essar OIL (UK) Limited | Manufacturing | 2009 |
| Essar Retail Ventures Limited | Wholesale & retail | 2019 |
| Esskay Dental Ltd | Health & social care | 2025 |
| Estate Assets Limited | Wholesale & retail | 2017 |
| Estate Planning & Probate Ltd | Professional & scientific | 2015 |
| Estoppel Concepts Ltd | Administrative & support | 2026 |
| Euchor Ltd | Professional & scientific | 2021 |
| Eurasia Rotating Equipment Services Ltd | Manufacturing | 2020 |
| European Underwater Federation | Other services | 2001 |
| EV Infinity Installations Ltd | Construction | 2024 |
| Eventainment Limited | Arts & recreation | 2016 |
| Events Photo Team Limited | Professional & scientific | 2008 |
| Everglade Ltd | Households | 2025 |
| Everlong Kitchen Respray Ltd | Construction | 2026 |
| Every JJ Properties Limited | Real estate | 2019 |
| Everything Horse Group Ltd | Manufacturing | 2013 |
| Evoke Group Ltd | Professional & scientific | 2012 |
| Evolution Films Partnership NO. 1 | | 2001 |
| Evolution Films Partnership NO. 10 | | 2001 |
| Evolution Films Partnership NO. 11 | | 2001 |
| Evolution Films Partnership NO. 12 | | 2001 |
| Evolution Films Partnership NO. 13 | | 2001 |
| Evolution Films Partnership NO. 2 | | 2001 |
| Evolution Films Partnership NO. 3 | | 2001 |
| Evolution Films Partnership NO. 4 | | 2001 |
| Evolution Films Partnership NO. 5 | | 2001 |
| Evolution Films Partnership NO. 6 | | 2001 |
| Evolution Films Partnership NO. 7 | | 2001 |
| Evolution Films Partnership NO. 8 | | 2001 |
| Evolution Films Partnership NO. 9 | | 2001 |
| Evolve Dental Academy Ltd | Health & social care | 2025 |
| Evolve Distance Learning Ltd | Professional & scientific | 2015 |
| Ewops Ltd | Professional & scientific | 2026 |
| Executive Insight Limited | Professional & scientific | 2005 |
| Expedmed Limited | Professional & scientific | 2011 |
| Export Italia Limited | Professional & scientific | 2009 |
| Exsupero Property Management Ltd | Real estate | 2022 |
| Eyaa Trading Ltd | Wholesale & retail | 2018 |
| EYE Love (Chester) Ltd | Other services | 2013 |
| Eyes of Swavesey Ltd | Wholesale & retail | 2014 |
| Eyewear Creations Limited | Wholesale & retail | 2006 |
| F B P Developments Ltd | Construction | 2021 |
| F B P Property Management Limited | Real estate | 2007 |
| Face by DR Grace Ltd | Health & social care | 2025 |
| Fairhurst Industrial Engineering Services Ltd | Professional & scientific | 2023 |
| Fairstay Homes Limited | Real estate | 2025 |
| Family SKI Company Ltd | Administrative & support | 1996 |
| FAMILY360 Limited | Arts & recreation | 2018 |
| Fast Runners Ltd | Transport & logistics | 2024 |
| Fastgo Ltd | Transport & logistics | 2019 |
| Fastpass Driving School Limited | Education | 2016 |
| Fauonix Limited | Information & communication | 2025 |
| Fawaz Medical Ltd | Health & social care | 2022 |
| Fcpdent Limited | Real estate | 2016 |
| Female Health Matters Ltd | Health & social care | 2022 |
| Female Health Matters T/A USE IT OR Lose IT UK Ltd | Professional & scientific | 2025 |
| Fenelon Holdings Ltd | Financial services | 2024 |
| Fenelon Storage Tanks Limited | Manufacturing | 2014 |
| Fenelon Storage UK Limited | Construction | 2013 |