| Scrub UP Medicine Ltd | Information & communication | 2026 |
| Scrubkilla Ltd | Arts & recreation | 2019 |
| Scrubup AI Limited | Information & communication | 2026 |
| Scruffinkle Deceased Limited | Hospitality | 2025 |
| Scruffy Dog Edinburgh Ltd | Other services | 2023 |
| Scrumcenter Limited | Information & communication | 2017 |
| Scryptcube Mining LP | | 2016 |
| SCT International LP | | 2016 |
| SCT68 Limited | Other services | 2021 |
| Scudetto Ltd | Administrative & support | 2025 |
| Scuff-Off Solutions Ltd | Wholesale & retail | 2025 |
| Sculantix Process Systems Limited | Wholesale & retail | 2026 |
| Sculatex Resources LP | | 2013 |
| Sculptherapy LP | | 2025 |
| Scurrex Logistics Limited | Transport & logistics | 2026 |
| Scurry Events Ltd. | Arts & recreation | 2017 |
| SCURRY2BRIDGES Limited | Arts & recreation | 2022 |
| SCW Developments Limited | Professional & scientific | 2020 |
| Scydonia Limited | Construction | 2012 |
| Scynex Conferences Ltd | Administrative & support | 2026 |
| SC_CV_3 LP | | 2016 |
| SC_CV_4 LP | | 2023 |
| SD Fitnesscoaching LP | | 2024 |
| SD Infinity Asset Management LP | | 2007 |
| SD Shipping LP | | 2017 |
| SDA Associates Limited | Professional & scientific | 2011 |
| Sdam Ventures Ltd | Hospitality | 2020 |
| SDB Lightshow Ltd | Arts & recreation | 2026 |
| SDC Diof IV FR Block a (Scots), L.P. | | 2024 |
| SDC Diof IV FR Block B (Scots), L.P. | | 2024 |
| SDC Diof IV FR Splitter a, L.P. | | 2024 |
| SDC Diof IV FR Splitter B, L.P. | | 2024 |
| SDC Diof Scots Temp GP Limited | Administrative & support | 2024 |
| SDC Ltd. | Construction | 2005 |
| Sdfoodedi Ltd | Wholesale & retail | 2026 |
| SDI International LP | | 2015 |
| SDI Productions Ltd | Information & communication | 2007 |
| SDK Group Limited | Manufacturing | 2016 |
| SDM Estates LP | | 2011 |
| SDM Partners Limited | Professional & scientific | 2011 |
| Sdps Properties Limited | Real estate | 2022 |
| SDR Property Company Ltd | Real estate | 2016 |
| SDR Property Developments Ltd | Construction | 2022 |
| SDR Property Residential Ltd | Real estate | 2025 |
| SDS Caspian Service LP | | 2013 |
| Sdvk Technologies Limited | Professional & scientific | 2025 |
| SE Choisir LP | | 2024 |
| SE Plus LP | | 2017 |
| SE Scotland City Tours Ltd | Administrative & support | 2026 |
| Sea & Land Inspections Ltd. | Professional & scientific | 2008 |
| Sea & Mountain Vans Ltd | Manufacturing | 2025 |
| Sea Air and Land Training (Salt) Services Ltd | Education | 2013 |
| Sea Engineering and Co | | 1991 |
| Sea Factor LP | | 2016 |
| Sea Foam Risk Management Ltd | Public administration | 2024 |
| Sea Force Group LP | | 2016 |
| Sea Freight Logistics LP | | 2016 |
| Sea Glass Inn Limited | Hospitality | 2019 |
| Sea Impex LP | | 2011 |
| Sea International Shipping Agent Ltd | Wholesale & retail | 2021 |
| Sea SAT Ltd | Professional & scientific | 2024 |
| Sea Trials North West Corp LP | | 2016 |
| Seab Finance Group LP | | 2016 |
| Seabass Vinyl Limited | Manufacturing | 2022 |
| Seabeach Nursery Limited | Health & social care | 2018 |
| Seaborne Trade Technical Advisors LP | | 2017 |
| Seabrew Coffee Ltd | Manufacturing | 2026 |
| Seabrick Capital LP | | 2012 |
| Seabuckthorn Scotland Community Interest Company | Agriculture & fishing | 2018 |
| Seabuoy Global Ltd | Information & communication | 2018 |
| Seaburg Systems L.P. | | 2016 |
| Seaceara Property Limited | Real estate | 2026 |
| Seacole National Centre (Holding) Limited | Professional & scientific | 2014 |
| Seacole National Centre Limited | Construction | 2014 |
| Seacraig Estates Limited | Real estate | 1978 |
| Seacrest International Ltd | Administrative & support | 2025 |
| Seadragon Holdco Limited | Financial services | 2023 |
| Seadyes Limited | Manufacturing | 2023 |
| Seafield Development LP | | 2014 |
| Seafield Hub Ltd | Arts & recreation | 2023 |
| Seafield Service and Repair Centre Limited | Wholesale & retail | 2016 |
| Seafield Services Ltd | Wholesale & retail | 2025 |
| Seafield Shed Centre Ltd | Wholesale & retail | 2014 |
| Seafield Valeting Centre Ltd | Administrative & support | 2025 |
| Seafield Vending Ltd | Wholesale & retail | 2022 |
| Seafood Trade L.P. | | 2009 |
| Seagrain LLP | | 2013 |
| Seagrave Investment Management Ltd | Professional & scientific | 2012 |
| Seagull Estates LP | | 2015 |
| Seagull Holdings | Professional & scientific | 1985 |
| Seahaven Properties Joppa Limited | Construction | 2016 |
| Seahawk Developments Limited | Real estate | 2016 |
| Seahorse Air Ltd | Professional & scientific | 2024 |
| Seahorse Coaching Limited | Education | 2023 |
| Seahorse Ocean Services Ltd. | Extraterritorial | 2018 |
| Seal Woman Productions Ltd | Information & communication | 2023 |
| Sealand Advisors LP | | 2015 |
| Sealine Investments 2 LP | | 2021 |
| Sealine Investments LP | | 2015 |
| Seam Property Ltd | Real estate | 2019 |