| Ricon Limited | Professional & scientific | 2004 |
| RID Struthers Limited | Professional & scientific | 2003 |
| RIDE4 Limited | Transport & logistics | 2025 |
| Ridersfield Limited | Professional & scientific | 2000 |
| Ridgeline Roofing & Building Ltd | Construction | 2024 |
| Ridley Roofing Limited | Construction | 2014 |
| Riggzy Complete Kitchen Solutions Limited | Construction | 2011 |
| Right on CUE Consulting Ltd | Professional & scientific | 2022 |
| Righttrack Motor Services Ltd | Wholesale & retail | 2011 |
| RIK Scott Creative Ltd. | Information & communication | 2014 |
| Ringcraft UK Ltd | Wholesale & retail | 2021 |
| Ripley Plumbing & Heating Limited | Construction | 2014 |
| Riplingham Meads Limited | Real estate | 2025 |
| Riplingham Meads RTM Company Ltd | Households | 2022 |
| Riptide Health and Fitness Ltd | Arts & recreation | 2014 |
| Riptide Limited | Arts & recreation | 2008 |
| Riptide Water Sports UK Limited | Extraterritorial | 2021 |
| Rise Above IT Limited | Arts & recreation | 2015 |
| Rise Joinery Ltd | Manufacturing | 2011 |
| Riskaware Training and Consultancy Ltd | Education | 2026 |
| Ritaa Beauty Limited | Other services | 2025 |
| Ritual Union Limited | Hospitality | 2021 |
| River of Life Church (Worthing) | Other services | 1997 |
| Riverbank Removals Limited | Transport & logistics | 2016 |
| Riverside Brasserie Lewis Ltd. | Hospitality | 2019 |
| Riverside Therapy Practice Ltd | Health & social care | 2014 |
| Riya Enterprise (UK) Limited | Real estate | 2021 |
| Riyan Holdings Limited | Financial services | 2019 |
| RJ Homes (Southern) Ltd | Real estate | 2023 |
| RJG Consultancy Services Limited | Information & communication | 2014 |
| RJM Digital Platforms Limited | Administrative & support | 2018 |
| RJP Diamond Forecasting Limited | Professional & scientific | 2002 |
| RJP Endodontics Limited | Health & social care | 2020 |
| RJR Electrical Contractors Limited | Construction | 2009 |
| RJS Communications Ltd | Information & communication | 2020 |
| RJU Holdings Limited | Real estate | 2025 |
| RK Electrical Installations Limited | Construction | 2019 |
| RL Healthcare Ltd | Health & social care | 2024 |
| RLB Purchasing Consultancy Limited | Information & communication | 2019 |
| RLG Tyres Ltd | Wholesale & retail | 2020 |
| RMA Conect Ltd | Transport & logistics | 2025 |
| RMS Dental Care Ltd | Health & social care | 2024 |
| Rnmlucky Ltd | Other services | 2026 |
| Rnsn Investments Limited | Financial services | 2021 |
| Rnsn Limited | Health & social care | 2017 |
| Road Adventures Limited | Professional & scientific | 2013 |
| Road Impressions Limited | Construction | 1997 |
| Roaming Hospitality Ltd | Hospitality | 2018 |
| Roar Pixels Ltd | Information & communication | 2019 |
| ROB Holmes Ltd | Financial services | 2021 |
| ROB Marshall Ltd | Information & communication | 2024 |
| ROB Samuelson International Limited | Administrative & support | 2007 |
| ROB Turley Ltd | Extraterritorial | 2012 |
| Rob-Art the LAD Ltd | Construction | 2025 |
| Robalex Services Ltd | Transport & logistics | 2018 |
| Robbie's Voice Ltd | Arts & recreation | 2011 |
| Robert Matthews Limited | Construction | 1987 |
| Roberts Home Solutions Ltd | Construction | 2024 |
| Robinson & Neal Limited | Wholesale & retail | 1905 |
| Robosparks Ltd | Construction | 2025 |
| Robsons of Lewes Limited | Hospitality | 1997 |
| Rock BOY Recording Studios Ltd | Manufacturing | 2020 |
| Rock Street Freehold Limited | Other services | 2020 |
| Rock Utilities Limited | Construction | 2026 |
| Rockaura Investments Limited | Real estate | 2022 |
| Rockvec Ltd | Information & communication | 2013 |
| Rodriguez Wholesale Limited | Wholesale & retail | 2017 |
| Roebuck Developments SE Ltd | Construction | 2024 |
| Roefield Engineering Limited | Professional & scientific | 2017 |
| Roger Simmons Ltd | Administrative & support | 2015 |
| Rogers International (UK) Limited | Manufacturing | 2003 |
| ROK International Limited | Professional & scientific | 2023 |
| Rolexis Care Ltd | Health & social care | 2017 |
| Roll Phoenix Ltd | Real estate | 2021 |
| Roll Sussex Limited | Hospitality | 2015 |
| Rollers Cafe Ltd | Hospitality | 2025 |
| Roman DEC Limited | Construction | 2026 |
| Roman Quality Services Ltd | Construction | 2026 |
| Romelo Ltd | Professional & scientific | 2026 |
| ROMELO2026 | Professional & scientific | 2026 |
| Romhar Ltd | Real estate | 2021 |
| Romsey Dental Care Limited | Health & social care | 2010 |
| Roncone Ltd | Administrative & support | 2020 |
| Ronningdale Group Limited | Wholesale & retail | 2025 |
| ROOM2LET Rentals Limited | Real estate | 2026 |
| Roots Gardening & Grounds Maintenance Limited | Administrative & support | 2014 |
| Ropb Consulting Limited | Other services | 2022 |
| Rosales Solutions Ltd | Manufacturing | 2026 |
| Rose Borges Surgery Ltd | Health & social care | 2015 |
| Rose Flooring Ltd | Construction | 2025 |
| Rose Orthopaedics Ltd | Health & social care | 2019 |
| Roseberry Eastbourne Ltd | Hospitality | 2024 |
| Rosebury Vets Ltd | Professional & scientific | 2025 |
| Rosebush Medical Limited | Health & social care | 2021 |
| Roselands Resourcing Ltd | Administrative & support | 2024 |
| Rosemount Nursery Bush Hill Park Limited | Health & social care | 2022 |
| Rosemullion Limited | Hospitality | 1998 |
| Roserent Limited | Wholesale & retail | 1996 |
| Rosetto Eastbourne Limited | Hospitality | 2015 |
| Rossand Consulting Limited | Professional & scientific | 2008 |