| Croft Glass Limited | Construction | 1994 |
| Cromwell Residents Association Limited | Households | 1991 |
| Crowborough Tennis & Squash Club Limited | Arts & recreation | 1987 |
| Crown Carpets Limited | Wholesale & retail | 2006 |
| Crown Oak Building Limited | Manufacturing | 2003 |
| Crows Nest Films Limited | Information & communication | 2003 |
| Croxgrove (Property Development) Limited | Wholesale & retail | 1977 |
| Cubeedobeedo Limited | Information & communication | 2006 |
| Cudlow Steel Services Limited | Manufacturing | 1985 |
| Cumberlege Connections Limited | Professional & scientific | 2003 |
| Curran Coaching Ltd | Professional & scientific | 2012 |
| Curtis Group Limited | Real estate | 1984 |
| Curtis Storage (Lancing) Limited | Real estate | 2000 |
| Cuthbert Property Limited | Real estate | 1961 |
| D & S Rees Bell Farm Limited | Professional & scientific | 2000 |
| D & V Large Autos Limited | Wholesale & retail | 2002 |
| D M Roofing Limited | Construction | 2002 |
| D Mamouchas Ltd | Health & social care | 2007 |
| D Sivers DRY Wall Construction Limited | Construction | 2002 |
| D Sovegjarto Flooring Ltd | Construction | 2007 |
| D V Moore Limited | Administrative & support | 2003 |
| D&S Tanks & Fabrications LLP | | 2006 |
| D. a. Vine Farms Ltd. | Agriculture & fishing | 1977 |
| D.A. Wills Limited | Construction | 2003 |
| D.S.C. Supplies (Holdings) Limited | Financial services | 2002 |
| D.Wales Plant Hire Limited | Wholesale & retail | 1994 |
| Daisy Gifts Limited | Wholesale & retail | 2002 |
| Dakota Print Limited | Manufacturing | 2003 |
| Dalespire Trade Limited | Wholesale & retail | 2026 |
| Dalmonach Limited | Real estate | 1965 |
| Daniel Adams Investments Limited | Real estate | 2003 |
| Darren Mason Limited | Construction | 2008 |
| Darwin Consultants Limited | Information & communication | 2002 |
| Data Advantage Ltd | Administrative & support | 2003 |
| Datanalytics Limited | Information & communication | 2008 |
| Dave Gould Properties LLP | | 2008 |
| David & Co Estate Agents Limited | Real estate | 2004 |
| David Downton Limited | Administrative & support | 2004 |
| David Pursey (Management) Limited | Real estate | 1995 |
| David Smith Jewellery Limited | Manufacturing | 2002 |
| David's Books & Comics Ltd | Wholesale & retail | 2006 |
| Davigdor Enterprise Limited | Health & social care | 2001 |
| Davigdor Properties Limited | Real estate | 2017 |
| DCF (UK) Ltd. | Financial services | 2001 |
| DD Controls Limited | Information & communication | 2004 |
| DDF Formwork Limited | Construction | 2005 |
| DDM Studios Ltd | Information & communication | 2007 |
| DE Courcy Developments Limited | Construction | 1987 |
| DE LA Warr Pavilion (Enterprises) Limited | Arts & recreation | 2003 |
| Dealerton Limited | Transport & logistics | 1986 |
| Debuk Limited | Arts & recreation | 1992 |
| Decimus Property Development Ltd | Construction | 2002 |
| Decon Laboratories Limited | Manufacturing | 1969 |
| Dee's Newsagents Limited | Wholesale & retail | 2003 |
| Deeceelee Ltd | Administrative & support | 2012 |
| Deevu Ltd | Information & communication | 2015 |
| Deklands Ltd. | Administrative & support | 1998 |
| Delaware Electronic Technology Limited | Professional & scientific | 1999 |
| Dellsop Limited | Education | 2003 |
| Delmec Limited | Construction | 2002 |
| Delves Retirement Homes Limited | Real estate | 1961 |
| Denis Evans(Holdings)Limited | Construction | 1952 |
| Dental Health Spa Limited | Health & social care | 2007 |
| Denton Island Indoor Bowls Club Ltd. | Arts & recreation | 1995 |
| Deon Link Consulting Limited | Information & communication | 1991 |
| Design LSM Limited | Professional & scientific | 1997 |
| Designerpaint Limited | Wholesale & retail | 2003 |
| DFB (Care) Limited | Health & social care | 2003 |
| Dgag Properties Ltd | Real estate | 2024 |
| DGB Aviation Consultants Ltd | Transport & logistics | 2007 |
| Diana Freedman School of Dance & Performing Arts Limited | Arts & recreation | 2002 |
| Dickies Suit Hire Limited | Administrative & support | 2002 |
| Diplocks Holdings Limited | Financial services | 2025 |
| Direct Business Solutions Limited | Information & communication | 1995 |
| Ditchling Rise Management Company Limited | Other services | 2004 |
| Diverse HR Services Limited | Administrative & support | 2007 |
| DJ Friendly Records Limited | Wholesale & retail | 2004 |
| Dolphin Leisure (UK) Limited | Administrative & support | 2003 |
| Dorhout Mees Limited | Extraterritorial | 2007 |
| Dorset House Management Company Limited | Households | 1990 |
| Downsford Limited | Households | 2003 |
| DR Margaret Mansi Limited | Other services | 2019 |
| Drevo Consulting Ltd | Professional & scientific | 2007 |
| Drivepoint Surfacing Limited | Construction | 1998 |
| Driver Training (Eastbourne) Ltd | Education | 2003 |
| Dufa Ltd | Arts & recreation | 2017 |
| Duncans Wood Limited | Agriculture & fishing | 2014 |
| Dunsfold Limited | Real estate | 1996 |
| Duverly Limited | Households | 1986 |
| Dwellans Limited | Real estate | 1996 |
| Dyersvil Maintenance Limited | Households | 1957 |
| Dyke Golf Club Limited | Arts & recreation | 1910 |
| Dynamicdevelopment Limited | Administrative & support | 1998 |
| Dynamix Group Limited | Professional & scientific | 2006 |
| Dyson Recycling Limited | Extraterritorial | 2005 |
| E-Tools.Co.Uk Ltd | Administrative & support | 2000 |
| E.N.V.Contractors Ltd. | Construction | 2002 |
| E.O. Culverwell Limited | Manufacturing | 1932 |
| E.S.K. Wholesale Limited | Wholesale & retail | 1980 |
| E3 Production Limited | Arts & recreation | 2006 |