| 14ELEVEN Consultancy Ltd | Professional & scientific | 2021 |
| 1STEP Social Limited | Hospitality | 2014 |
| 37 Studios Ltd | Wholesale & retail | 2014 |
| A & a Scaffolding (NE) Ltd | Construction | 2022 |
| A Barber (South Shields) Ltd | Other services | 2025 |
| A-One (NE) Limited | Construction | 2010 |
| A.B. Gusto Ltd | Hospitality | 2022 |
| Abkm Properties Limited | Households | 2024 |
| Accom 4YOU Limited | Wholesale & retail | 2013 |
| Addictions North East | Health & social care | 2004 |
| Addictions UK Ltd | Health & social care | 2006 |
| Adept Integrated Solutions Limited | Professional & scientific | 2009 |
| Adept Property Limited | Real estate | 2025 |
| Aegis Consulting Services Limited | Professional & scientific | 2024 |
| Agile and Scrum Development Ltd | Information & communication | 2015 |
| AH Enterprises (Hull) Ltd | Other services | 2009 |
| AHS Engineering Services Ltd | Construction | 2023 |
| Aiskew Assessment and Training Services Ltd | Administrative & support | 2017 |
| Ali's Pizza Kebab House Ltd | Hospitality | 2021 |
| Alidrium Properties Ltd | Real estate | 2023 |
| ALM Brand Consultancy Ltd | Administrative & support | 2016 |
| Alpha Building & Carpentry Ltd | Construction | 2023 |
| Altun Consultancy Ltd | Professional & scientific | 2021 |
| Amelis Engineering Solutions Ltd | Construction | 2015 |
| Amma Helping Centre | Education | 2024 |
| Ampcore Ltd | Construction | 2025 |
| Amusg Ltd | Health & social care | 2018 |
| Andre-Marcel Consultancy Ltd | Professional & scientific | 2024 |
| Anglo American Industries Ltd | Professional & scientific | 2011 |
| ANY2 Investments Limited | Construction | 2007 |
| Apex Hull Ltd | Professional & scientific | 2021 |
| APS Properties (NE) Ltd | Other services | 2022 |
| AR Robson Logistics Ltd | Transport & logistics | 2025 |
| Arbeia Finance Ltd | Financial services | 2026 |
| Arbour Developments NE Ltd | Real estate | 2024 |
| Armstrong Hall Social Club Ltd | Hospitality | 2012 |
| Aspect Mountain Films Ltd | Information & communication | 2026 |
| Asset Management Consultancy Services U.K. Ltd | Professional & scientific | 2023 |
| Atlas Freight (NE) Ltd | Transport & logistics | 2016 |
| Avenue Joinery Ltd | Construction | 2023 |
| B L News Limited | Other services | 2013 |
| B.C.I. (Stretchers) Limited | Manufacturing | 2000 |
| B.C.I. Hotels Limited | Hospitality | 2017 |
| Bamburgh Holdings Limited | Financial services | 2021 |
| Bamburgh Leisure Limited | Hospitality | 2023 |
| Barramix Limited | Transport & logistics | 2009 |
| Bear Burners Ltd | Manufacturing | 2021 |
| Bell and SON Home Improvements Ltd | Construction | 2024 |
| Bellgate Enterprises Limited | Financial services | 2014 |
| Benmahar Ltd | Information & communication | 2023 |
| BHU Engineering Consultancy Limited | Professional & scientific | 2019 |
| Bigfoot Arts Education (North East) Ltd | Arts & recreation | 2012 |
| Birrell Estates Ltd | Real estate | 2026 |
| Blacks Corner Retail Company Ltd | Hospitality | 2016 |
| Blacks Corner Trading Company Ltd | Wholesale & retail | 2016 |
| Blazemint Ltd | Other services | 2009 |
| Blockyard Brew Co Ltd | Manufacturing | 2022 |
| Boba Empire Ltd | Hospitality | 2021 |
| Boho and Sage Ltd | Other services | 2025 |
| Boldon Auction Galleries Limited | Wholesale & retail | 2011 |
| Boldon Electrical Installation Company Limited | Construction | 2008 |
| Boldon Holdings Limited | Other services | 2019 |
| Brandling Junction Ltd | Hospitality | 2025 |
| Bright Dale Ltd | Public administration | 2025 |
| Byron Drywall Limited | Construction | 2019 |
| Campbell Industrial Service Ltd | Construction | 2016 |
| Capital Professional Services Ltd | Professional & scientific | 2018 |
| Caterpilla Limited | Information & communication | 2024 |
| Cavaliere Ltd | Hospitality | 2026 |
| Celex Electricals Ltd | Construction | 2024 |
| Chard Works Limited | Real estate | 2022 |
| Cherry & Co Consultancy Ltd | Arts & recreation | 2021 |
| City Aesthetics Limited | Other services | 2019 |
| City Skin North East Ltd | Other services | 2021 |
| Cleadon MOT Centre Ltd | Wholesale & retail | 2025 |
| Cleadon Motor Company Ltd | Wholesale & retail | 2025 |
| Cleadon Property Development Ltd | Extraterritorial | 2020 |
| Clinic NO5 Ltd | Health & social care | 2024 |
| Clinic NO5 Medical Training Ltd | Health & social care | 2019 |
| Clockwork Innovations Ltd | Professional & scientific | 2022 |
| Cockahoop Creative CIC | Arts & recreation | 2025 |
| Colinas Estates Ltd | Construction | 2017 |
| Colinas Property Investment Ltd | Real estate | 2018 |
| Complai Ltd | Information & communication | 2024 |
| Continental Hotel Hull Ltd | Hospitality | 2024 |
| Converted Media Ltd | Information & communication | 2005 |
| Coote O'Grady Ltd | Professional & scientific | 2016 |
| Cornell Properties Ltd | Real estate | 2022 |
| Cottage Hideaways Ltd | Real estate | 2022 |
| Crab and Lobster Limited | Extraterritorial | 2001 |
| Crown Design Hairdressing Ltd | Other services | 2012 |
| Crystal Blinds (NE) Ltd | Wholesale & retail | 2012 |
| D & a Colour Bar Limited | Other services | 2012 |
| D & J Clapham Ltd | Manufacturing | 2013 |
| D Wood Property Services Ltd | Real estate | 2025 |
| D&E Hairdressing Ltd | Other services | 2025 |
| DAN Holden Signature Kitchens and Interiors Ltd | Professional & scientific | 2024 |
| Dave Stuart Electrical Ltd | Construction | 2008 |
| David Fairbairn Automotive Ltd | Wholesale & retail | 2015 |
| DBH Safety Ltd | Professional & scientific | 2024 |