| Red Rose Durham Limited | Real estate | 2017 |
| Red ROW Productions Ltd | Administrative & support | 2017 |
| Red Ruby Financial Ltd | Financial services | 2018 |
| Red Shed Lets Limited | Real estate | 2022 |
| Redhills Trading Company Ltd | Arts & recreation | 2025 |
| Redkite Digital Solutions Limited | Professional & scientific | 2017 |
| Redline Professional Services Limited | Professional & scientific | 2024 |
| Redshaw Construction Ltd | Construction | 2026 |
| Reece of London Ltd | Wholesale & retail | 2018 |
| Reece Sibbald Productions Ltd | Arts & recreation | 2019 |
| Reef Salons Limited | Wholesale & retail | 2012 |
| Reel 'EM' in Ltd | Wholesale & retail | 2025 |
| Reeverenovations Ltd | Construction | 2026 |
| Refco Farms Ltd | Agriculture & fishing | 2014 |
| REFEREE4U Ltd | Arts & recreation | 2026 |
| Refine Aesthetics Durham Ltd | Other services | 2025 |
| Reflect Business Solutions Ltd | Professional & scientific | 2013 |
| Reflections Hair & Design Ltd | Other services | 2015 |
| Refyn Consultancy Services Ltd | Professional & scientific | 2025 |
| REG Dealers Limited | Wholesale & retail | 2020 |
| Regal Company Management Ltd | Wholesale & retail | 2025 |
| Reger Holding Limited | Real estate | 2007 |
| Reger Property Limited | Real estate | 2007 |
| Reggie T Landscapes Limited | Administrative & support | 2024 |
| Rehab-Link Limited | Health & social care | 2016 |
| Reiver Marketing Limited | Administrative & support | 1996 |
| Relco Software Ltd | Information & communication | 2022 |
| REM Holding Ltd | Real estate | 2024 |
| Remodel Ltd | Construction | 2023 |
| Renaissance Land Management Limited | Real estate | 2006 |
| Renaissance Land Regeneration Limited | Financial services | 2004 |
| Rend Holdings Limited | Financial services | 2023 |
| Renegade Design Studio Ltd | Professional & scientific | 2024 |
| Renewable Energy Management Ltd | Construction | 2023 |
| Renovere Group Limited | Financial services | 2024 |
| Renovere Homes Limited | Construction | 2024 |
| Renovere Properties Limited | Real estate | 2024 |
| Renowork Group Ltd | Construction | 2025 |
| Renroc Property Limited | Real estate | 2020 |
| Reprotec UK Limited | Construction | 1980 |
| Res-Rt Limited | Transport & logistics | 2024 |
| Resolute Experiences (UK) Limited | Administrative & support | 2019 |
| RESON8 Consulting Ltd | Professional & scientific | 2024 |
| Respiratone Limited | Manufacturing | 2022 |
| Response Property Services Global Ltd | Real estate | 2022 |
| Result Fitness Limited | Arts & recreation | 2014 |
| Resurgam PUB Company Ltd | Hospitality | 2023 |
| Reswing Golf Limited | Wholesale & retail | 2023 |
| Retainers Direct Limited | Health & social care | 2020 |
| Revamp Limited | Manufacturing | 2001 |
| REX Engineering Ltd | Construction | 2016 |
| Rfid Tags Limited | Information & communication | 2010 |
| RG Developments NE Ltd | Construction | 2017 |
| RG Lets Ltd | Real estate | 2026 |
| RG Web Limited | Wholesale & retail | 2024 |
| RH (York) Management Company Limited | Households | 2019 |
| RH Dental Ltd | Health & social care | 2025 |
| RH Groundworks NE Ltd | Construction | 2026 |
| Rhino Racking Ltd | Wholesale & retail | 2021 |
| Rhodes Logitics Ltd | Transport & logistics | 2025 |
| Rhombus Technology Limited | Information & communication | 2015 |
| Rhpb Ltd | Financial services | 2015 |
| Rhpd Services Ltd | Water & waste | 2024 |
| Ribble Avenue 1960 Limited | Extraterritorial | 2014 |
| Ribchesters Group Limited | Professional & scientific | 2013 |
| Rice Property Services Limited | Households | 2000 |
| Richard Chalmers Limited | Health & social care | 2020 |
| Richard Robley Chiropody & Mobility Limited | Health & social care | 2011 |
| Richardson Designs Limited | Manufacturing | 1986 |
| Richmond Raven Limited | Information & communication | 2015 |
| Ridgeline View Limited | Real estate | 2025 |
| Ridley Grinding Ltd | Construction | 2017 |
| Right Art Limited | Manufacturing | 2023 |
| Right Hook Studio Ltd | Information & communication | 2019 |
| Right Shopping Ltd | Wholesale & retail | 2025 |
| Rightworx Ltd | Wholesale & retail | 2010 |
| Rigtec Site Services Ltd | Construction | 2023 |
| Riley Langdon Solicitors Limited | Extraterritorial | 2011 |
| RIO Holdings (Hull) Limited | Financial services | 2021 |
| RIO Property (Hull) Limited | Real estate | 2021 |
| RIO Stowell Limited | Professional & scientific | 2020 |
| Riod Ltd | Manufacturing | 2022 |
| Ripon Riverside Auto Ltd | Professional & scientific | 2025 |
| Ripple Studios Ltd | Professional & scientific | 2018 |
| Risinxtreme Limited | Wholesale & retail | 2022 |
| Risqandacc Limited | Wholesale & retail | 2025 |
| Rite Networks Limited | Professional & scientific | 1999 |
| Ritual Beauty Ltd | Administrative & support | 2023 |
| Ritual Beauty Training Ltd | Other services | 2023 |
| Ritual Property Ltd | Real estate | 2023 |
| River Pont Consortium Limited | Professional & scientific | 2024 |
| Riverside Brickworks Limited | Construction | 2026 |
| Riverside Company Management Ltd | Wholesale & retail | 2025 |
| Riverside Leisure (Hexham) Limited | Hospitality | 2005 |
| Riverside Sixty Five Limited | Real estate | 2026 |
| Riverview Kitchen 56 Ltd | Hospitality | 2022 |
| Riverwalk Nails and Beauty Ltd | Other services | 2019 |
| Rizfat Trading Limited | Wholesale & retail | 2020 |
| RJ Commercial (NE) Ltd | Professional & scientific | 2021 |
| RJ Properties (NE) Ltd | Real estate | 2022 |