| Spa & Co London (UK) Limited | Extraterritorial | 2019 |
| SPB Custom Metalworks Limited | Construction | 2008 |
| SPC BMS Controls Ltd | Manufacturing | 2022 |
| Specialist Insulation Supplies Limited | Construction | 1989 |
| SPI Tax Ltd | Professional & scientific | 2018 |
| Spice of Dunmow Ltd | Hospitality | 2025 |
| Spiral HR Ltd | Professional & scientific | 2019 |
| Spirit Wealth Limited | Wholesale & retail | 2021 |
| Spitalfields PUB Company Limited | Hospitality | 2010 |
| Spoelstra Ltd. | Other services | 2012 |
| Sportropolis Limited | Arts & recreation | 2023 |
| Sports Showreel Ltd | Professional & scientific | 2014 |
| Spray Wrap Ltd | Wholesale & retail | 2026 |
| Spraytec Limited | Agriculture & fishing | 1997 |
| Sprint Couriers (UK) Limited | Transport & logistics | 2011 |
| Spudz N Sips Ltd | Hospitality | 2025 |
| Square Productions Ltd | Administrative & support | 2009 |
| Squire King Associates Limited | Professional & scientific | 1992 |
| SRP Plumbing and Heating Services Ltd | Construction | 2020 |
| Ssavfit Ltd | Other services | 2024 |
| ST Communication Solutions Ltd | Other services | 2013 |
| ST Cuthberts Walk (GP1) Limited | Extraterritorial | 2006 |
| ST Cuthberts Walk (GP2) Limited | Extraterritorial | 2006 |
| ST Mary's Mews Essex Management Company Limited | Households | 2019 |
| Stable Yard Residents Limited | Households | 1998 |
| Standley ALL Things Property Ltd | Real estate | 2025 |
| Stanley Frank Ltd | Wholesale & retail | 2024 |
| Stansted Estates Limited | Real estate | 1998 |
| Starbridge Property Investment Limited | Real estate | 2016 |
| Starling One Limited | Real estate | 2020 |
| Stately Events Ltd | Administrative & support | 2022 |
| Stay Fit Essex Limited | Arts & recreation | 2017 |
| Stayyna Dingle Limited | Hospitality | 2016 |
| Stayyna Iveragh Limited | Hospitality | 2021 |
| STC 24HR Recovery Ltd | Wholesale & retail | 2023 |
| Stebbing Montessori Limited | Education | 2006 |
| Steerson Developments (Cambridge) Limited | Construction | 2022 |
| Steerson Homes Limited | Construction | 2022 |
| Steerson Living Ltd | Real estate | 2019 |
| Steerson Property Management Ltd | Real estate | 2023 |
| Steph Evans Ltd | Professional & scientific | 2020 |
| Stephane Conrard Limited | Information & communication | 2025 |
| Steve Ware Brokerage Limited | Financial services | 2025 |
| Stevens Lane Management Company Ltd | Real estate | 2021 |
| Stoic Design Limited | Professional & scientific | 2003 |
| Stoicathlete Ltd | Education | 2025 |
| Stonehouse Foods Ltd | Wholesale & retail | 2018 |
| Storehouse Safety Limited | Wholesale & retail | 2004 |
| Stowsted Ltd | Hospitality | 2020 |
| Strada Building & Maintenance Limited | Construction | 1996 |
| Strathyx Building Systems Limited | Construction | 2026 |
| Stratos Property Limited | Real estate | 2007 |
| Strongman Support Services Ltd | Administrative & support | 2020 |
| Stubbs Associates Ltd | Professional & scientific | 2019 |
| Studio 1224 Limited | Arts & recreation | 2026 |
| Sturgess and Co. Ltd | Professional & scientific | 2009 |
| Substantus Limited | Real estate | 2012 |
| Suffolk Electrical Wholesale Ltd | Transport & logistics | 2008 |
| Summit Sound & Light Ltd | Administrative & support | 2026 |
| Sunbank Estate Management Limited | Households | 1983 |
| Sunbathers Health & Beauty Cheshunt Limited | Other services | 2010 |
| Sunbathers Health & Beauty Potters Bar Limited | Other services | 2012 |
| Sunbathers Tanning Chelmsford Ltd. | Other services | 2015 |
| Sunnybrook Developments Limited | Real estate | 2023 |
| Supalawns Limited | Professional & scientific | 2014 |
| Superfly Collective Ltd. | Administrative & support | 2025 |
| Supertan Sunbed Hire Limited | Other services | 2008 |
| Supply OPS Consulting Limited | Professional & scientific | 2025 |
| Support Send Kids Limited | Education | 2020 |
| Support Send Kids Trading Limited | Information & communication | 2021 |
| Sure Homes Nationwide Ltd | Real estate | 2025 |
| Susannah's Kitchen LLP | | 2025 |
| SW Drain Solutions Ltd | Other services | 2025 |
| Swift Exchange Ltd | Administrative & support | 2020 |
| Swiftsure Safety Solutions Ltd | Construction | 2025 |
| Sygma Telecommunications Limited | Information & communication | 2010 |
| Synergia Enterprises Limited | Information & communication | 2013 |
| Synergy Project Solutions Ltd | Administrative & support | 2025 |
| System Sense Technology Limited | Information & communication | 2002 |
| T & S Building Limited | Construction | 2006 |
| T C Property Investments Ltd | Real estate | 2012 |
| T G Physio Limited | Health & social care | 2022 |
| T MCL Catering Hire Limited | Hospitality | 2015 |
| T Wilson Aviation Ltd | Education | 2023 |
| T&I Invest 1 Ltd | Real estate | 2019 |
| T'S and C'S Cafe Limited | Other services | 2018 |
| T.J. Green (Pension Consultants) Limited | Financial services | 1984 |
| T.J.Atkinson(Ingatestone)Limited | Wholesale & retail | 1966 |
| Tabernacle Capital Holdings Limited | Real estate | 2017 |
| Take IT Away Ltd | Transport & logistics | 2024 |
| Tapfield Lettings Limited | Hospitality | 2022 |
| Tara Jewels Ltd | Wholesale & retail | 2025 |
| Target 4 U Limited | Construction | 2008 |
| Taylor Brookes Limited | Real estate | 2010 |
| Taylor Brookes South East Limited | Administrative & support | 2015 |
| TBS Design & Build Limited | Construction | 2025 |
| TBS L&P Ltd | Professional & scientific | 2015 |
| Teaden Properties Ltd | Real estate | 2022 |
| Tech-Desk Tech Support Limited | Information & communication | 2024 |
| Technical Air Ltd | Construction | 2024 |