| Rutt Engineering Limited | Professional & scientific | 2005 |
| Ryan & Co Heating Limited | Construction | 2012 |
| RYE House Rockets Ltd | Arts & recreation | 2019 |
| S a Jones Contracts Limited | Manufacturing | 2007 |
| S E Security Solutions Limited | Construction | 2021 |
| S Kutty Limited | Health & social care | 2010 |
| S R B Contracts Limited | Other services | 2008 |
| S Roscoe Electrical Limited | Construction | 2017 |
| S&B Jackson Limited | Other services | 2026 |
| S&P Fixing Ltd | Construction | 2015 |
| S.P.R Private Wealth Ltd | Administrative & support | 2025 |
| S.R. Gali Ltd | Construction | 2023 |
| Sachi & Bear Limited | Administrative & support | 2024 |
| Saleslogic Emea Recruitment Ltd | Administrative & support | 2018 |
| Saleslogic Recruitment Limited | Other services | 2013 |
| Salon 7 (Takeley) Limited | Other services | 2013 |
| Salon Guru Ltd | Information & communication | 2014 |
| Salter-Paterson Hospitalities Limited | Hospitality | 2020 |
| Sandypand Ltd | Hospitality | 2025 |
| Sarex Properties Limited | Real estate | 2006 |
| Sarh Investments Ltd | Real estate | 2023 |
| Sascha MAY Limited | Information & communication | 2007 |
| Save the Ice Cream Limited | Arts & recreation | 2022 |
| Saxon Supply Ltd | Information & communication | 2019 |
| SBC HR Limited | Administrative & support | 2023 |
| SC4 Recruitment Limited | Administrative & support | 2020 |
| Scene & Herd Media Ltd | Information & communication | 2025 |
| Schnappy Ltd | Manufacturing | 2018 |
| Scholfield Events Ltd | Administrative & support | 2020 |
| Scour and Sparkle Ltd | Administrative & support | 2025 |
| Scridain Limited | Health & social care | 2014 |
| Sd&Sf Ltd | Wholesale & retail | 2024 |
| SDB Building Contractors Ltd | Construction | 2019 |
| Seagrove Homes Limited | Construction | 2013 |
| Seasons Hospitality Group Limited | Hospitality | 2025 |
| Secretary-General Limited | Professional & scientific | 2001 |
| Sedon Construction Ltd | Construction | 2018 |
| Select Pool Services Ltd | Administrative & support | 2022 |
| Semaeopus Ltd. | Information & communication | 2014 |
| Seneca Leadership Limited | Administrative & support | 2013 |
| Series Parts Ltd | Wholesale & retail | 2021 |
| Sfph Ltd | Real estate | 2020 |
| SGN Limited | Wholesale & retail | 2016 |
| Sgtt Holdings Limited | Financial services | 2025 |
| Shandra Property Co Limited | Real estate | 2014 |
| SHE Builds Systems Limited | Wholesale & retail | 2024 |
| Sheek Retail Ltd | Wholesale & retail | 2024 |
| Sheeks Cakes Ltd | Hospitality | 2013 |
| Shepherds Health Ltd | Other services | 2015 |
| Sherman Terra Limited | Construction | 2001 |
| Sherris Properties Limited | Real estate | 2022 |
| Shieling Lands Limited | Professional & scientific | 2000 |
| Shine a Light 75 Ltd | Wholesale & retail | 2021 |
| Show Home Stone Ltd | Manufacturing | 2019 |
| Siapet Limited | Professional & scientific | 2026 |
| Sienna Cafe Limited | Hospitality | 2023 |
| Sighthound Life Science Consulting Ltd | Professional & scientific | 2025 |
| Sigmachi Ltd | Professional & scientific | 2026 |
| Silo Games Limited | Information & communication | 2014 |
| Silver Surf Conversions Limited | Wholesale & retail | 2016 |
| Silver Tree Group Ltd | Administrative & support | 2017 |
| Silver Tree Windows and Doors Ltd | Administrative & support | 2017 |
| Silvertree Consulting Ltd | Professional & scientific | 2013 |
| Silvertree Nutrition Limited | Administrative & support | 2022 |
| Simbeo Limited | Administrative & support | 2019 |
| Simpleppc Ltd | Professional & scientific | 2017 |
| Simply Sanding (UK) Limited | Administrative & support | 2007 |
| Simply Sanding Limited | Construction | 2013 |
| Sitecore Contractors Ltd | Construction | 2026 |
| SIX String Services Limited | Information & communication | 2024 |
| SJ Shelton Dairies Ltd | Wholesale & retail | 2024 |
| SJA Property Company Ltd | Real estate | 2021 |
| SJA Vehicles Ltd | Administrative & support | 2021 |
| SJB Legal Consultants Ltd | Other services | 2016 |
| SJP Fire Safety Ltd | Professional & scientific | 2024 |
| SJW Farms Limited | Agriculture & fishing | 2026 |
| Skinny PIG Interiors Ltd | Wholesale & retail | 2021 |
| Skylark Research Ltd | Professional & scientific | 2019 |
| Sloane Associates Limited | Professional & scientific | 2026 |
| Smart Fast Consulting Ltd | Information & communication | 2021 |
| Smartcompanyfinance Limited | Financial services | 2018 |
| SMB Trade Contractors Limited | Construction | 2022 |
| Smith Bailey Properties Limited | Real estate | 2021 |
| Smith-Bailey Investment Properties Limited | Households | 2021 |
| Smooth Dimensions Essex Limited | Health & social care | 2024 |
| Smooth Move Lets Limited | Real estate | 2023 |
| Snooty Lions Limited | Information & communication | 2019 |
| Snot & Bother Limited | Wholesale & retail | 2020 |
| Snowdon Construction Limited | Construction | 2015 |
| SO Human Resources Ltd | Professional & scientific | 2016 |
| Socialstudio Digital Limited | Professional & scientific | 2025 |
| Softov Limited | Information & communication | 2025 |
| Solace Box Company Ltd | Wholesale & retail | 2018 |
| Solertia Management Limited | Professional & scientific | 2025 |
| Solum Landscape Contractors Ltd | Construction | 2020 |
| Sonitt Limited | Administrative & support | 2023 |
| Sortan Ltd | Wholesale & retail | 2026 |
| Sosa Dance Ltd | Arts & recreation | 2012 |
| Soul Sure Ltd | Other services | 2026 |
| Sovereign Wellness Ltd | Wholesale & retail | 2025 |