| Seanclarksparks Ltd | Construction | 2025 |
| Seann Aois Limited | Real estate | 2021 |
| Seasky Limited | Professional & scientific | 2009 |
| Seaton Catering Limited | Hospitality | 2011 |
| Seatrader Dundee Ltd | Real estate | 2025 |
| Seaview Yachts Limited | Financial services | 2025 |
| Seaway Chippy Limited | Wholesale & retail | 2026 |
| Seaway Properties Limited | Real estate | 2021 |
| Seaway Storage Limited | Transport & logistics | 2025 |
| Seaway Trading Limited | Hospitality | 2019 |
| Sebastian & Co Estate Ltd | Real estate | 2025 |
| Sebastian's Home Renovations Ltd | Construction | 2026 |
| Sebbers Lifting Ltd | Construction | 2022 |
| Sebriel Limited | Construction | 2022 |
| Secuk Limited | Professional & scientific | 2019 |
| Securitay Limited | Administrative & support | 1996 |
| Sedalgo Ltd | Wholesale & retail | 2019 |
| SEE GEE LAB Ltd | Information & communication | 2025 |
| Seenroy Ltd | Manufacturing | 2025 |
| Seggiehill Ltd | Real estate | 2020 |
| Segway Ecosse Ltd. | Administrative & support | 2012 |
| Sekers Fabrics Limited | Administrative & support | 1998 |
| Sekodia Limited | Professional & scientific | 2014 |
| Selan Design Limited | Professional & scientific | 1989 |
| Select Dundee Ltd | Real estate | 2021 |
| Select Epos Ltd | Wholesale & retail | 2026 |
| Select Fireplace & Stove Company Ltd. | Wholesale & retail | 2002 |
| Select Fireplace Company Ltd. | Wholesale & retail | 2015 |
| Select Soft Furnishings Limited | Manufacturing | 2015 |
| Select Wallpaper Limited | Wholesale & retail | 2003 |
| Semele LP | | 2017 |
| Semestry Limited | Information & communication | 2013 |
| Sena 7 Solutions Ltd | Professional & scientific | 2025 |
| Senbonsakura Ltd | Hospitality | 2026 |
| Sendix AI Ltd | Information & communication | 2026 |
| Senidel Projects LP | | 2017 |
| Senior Capital LP | | 2017 |
| Senior Technical Services L.P. | | 2012 |
| Seniors Cricket (Scotland) Limited | Arts & recreation | 2025 |
| Senmac Heating Solutions Ltd | Construction | 2023 |
| Senrac Consulting Ltd | Professional & scientific | 2022 |
| Seon Consultancy Ltd | Professional & scientific | 2022 |
| Sepang Properties Limited | Real estate | 2017 |
| Sepflo Ltd | Professional & scientific | 2013 |
| Serach Limited | Real estate | 2024 |
| Serandib Events Ltd | Hospitality | 2025 |
| Seras Services Ltd | Professional & scientific | 2023 |
| Serendipitay Ltd | Other services | 2025 |
| Serenitay Ltd | Other services | 2025 |
| Service Design Academy Limited | Professional & scientific | 2025 |
| Session Food UK Ltd | Hospitality | 2024 |
| SET Training and Resourcing Limited | Administrative & support | 2013 |
| Setrday Ltd | Transport & logistics | 2025 |
| Seven 8 SIX (Tayside) Limited | Real estate | 2005 |
| Seventeen Acres Ltd | Agriculture & fishing | 2025 |
| Sevenza Limited | Wholesale & retail | 2025 |
| Severo Capital LP | | 2017 |
| Seymour Lodge Ltd | Education | 2025 |
| Seán Dillon Sports Ltd | Arts & recreation | 2019 |
| SFW Holdings Limited | Financial services | 2023 |
| SFW Investments Limited | Financial services | 2018 |
| SFW Limited | Administrative & support | 2023 |
| Sfwm Corporate Services Ltd | Administrative & support | 2023 |
| SG Auto Services Limited | Wholesale & retail | 2017 |
| SG Electrical & RA Limited | Construction | 2020 |
| SG Fitness Blairgowrie Ltd | Arts & recreation | 2021 |
| SG Lawson Limited | Manufacturing | 2019 |
| SG Living Spaces Ltd | Households | 2025 |
| SGG Electrical (Dundee) Ltd | Construction | 2017 |
| Sgka Ltd | Construction | 2025 |
| SGL Financial Services Ltd | Financial services | 2022 |
| SGL Investment 2 Ltd | Real estate | 2018 |
| SGL Investment 3 Ltd | Real estate | 2020 |
| SGL Investment 4 Ltd | Real estate | 2021 |
| SGL Investment Ltd | Real estate | 2016 |
| SGL Property Limited | Real estate | 2009 |
| SGX Ltd | Administrative & support | 2025 |
| Shaam Properties Ltd | Real estate | 2023 |
| Shaandar (Dundee) Limited | Extraterritorial | 2022 |
| Shackleton Technologies (Holdings) Limited | Information & communication | 2011 |
| Shackleton Technologies Ltd | Information & communication | 2004 |
| Shadow Developments Limited | Construction | 2021 |
| Shaftesbury Hotel Dundee Ltd | Hospitality | 2018 |
| Shaftesbury Restaurant Dundee Limited | Hospitality | 2022 |
| Shahz Scotland Ltd | Wholesale & retail | 2018 |
| Shajar Limited | Real estate | 2016 |
| Shak Taxis Limited | Transport & logistics | 2024 |
| Shamco Ltd | Households | 2026 |
| Shampooch Dog Grooming Ltd | Other services | 2021 |
| Shamrock Ecosse R C Ltd | Arts & recreation | 2023 |
| Shamrock Property Limited | Real estate | 2025 |
| Shaper Caper Limited | Arts & recreation | 2015 |
| Shapla Alba Limited | Administrative & support | 2013 |
| Sharif Trading Whitburn Limited | Wholesale & retail | 2017 |
| Sharp Integrated Services Limited | Professional & scientific | 2015 |
| Sharpe Solutions (Consultancy) Limited | Administrative & support | 2016 |
| Shaundrummmond Courier Ltd | Transport & logistics | 2025 |
| Shax Burger Ltd | Hospitality | 2019 |
| Shax Dundee Ltd | Real estate | 2018 |
| Shaz Services International Ltd | Transport & logistics | 2023 |