| Superior Machines Ltd | Manufacturing | 2009 |
| Sustain a BOO Limited | Wholesale & retail | 2019 |
| Suzanna Maria Emmanuel Limited | Health & social care | 2020 |
| Swanland Mortgages Limited | Financial services | 2014 |
| Swaythorpe Growers Limited | Agriculture & fishing | 1996 |
| Sykul and Ryde Ltd | Wholesale & retail | 2025 |
| T B Clappison Limited | Agriculture & fishing | 1992 |
| T E Wells & Sons Limited | Agriculture & fishing | 2008 |
| T M Enterprises Limited | Real estate | 1975 |
| T W Bell & Sons (Holdings) Limited | Professional & scientific | 2009 |
| T W Driffield Ltd | Hospitality | 2019 |
| T&C Cleaning Contractors Ltd | Administrative & support | 2026 |
| T. W. Bell & Sons (Farmers) Limited, | Agriculture & fishing | 1963 |
| T3D Visions Limited | Professional & scientific | 2025 |
| Tails N' Trails Dog Walking Ltd | Other services | 2019 |
| Tanker Trans Limited | Transport & logistics | 2007 |
| Taylor Plant Machinery Limited | Wholesale & retail | 2013 |
| TCH Construction Limited | Construction | 2021 |
| TD Projects Limited | Administrative & support | 2005 |
| Tdcip Ltd | Information & communication | 2025 |
| Team Transform Limited | Arts & recreation | 2015 |
| TED Homes Yorkshire Limited | Real estate | 2023 |
| Teleware Limited | Information & communication | 2003 |
| Templand Cottages Limited | Real estate | 1958 |
| Teresa Chalmers Marketing Ltd | Professional & scientific | 2006 |
| TF Motor Group Ltd | Wholesale & retail | 2026 |
| Thames Diesel Limited | Wholesale & retail | 2023 |
| THE Ace of Vapez Wholesale Limited | Manufacturing | 2015 |
| THE Anvil Arms NK Wold Limited | Hospitality | 2024 |
| THE Apple of My I Ltd | Professional & scientific | 2006 |
| THE Black Bull (Barmston) Limited | Hospitality | 2024 |
| THE Butchers Dog Driffield Ltd | Hospitality | 2014 |
| THE Cask & Flame Ltd | Hospitality | 2025 |
| THE Cathedral Scaffold Company Ltd | Administrative & support | 2002 |
| THE CDA Organisation Limited | Administrative & support | 2013 |
| THE Cross Keys (Petros) Limited | Hospitality | 2009 |
| THE Dales Sweep Ltd | Administrative & support | 2012 |
| THE Despatch Company Ltd | Information & communication | 2015 |
| THE Driffield Fruit Centre Limited | Wholesale & retail | 1997 |
| THE Driffield Navigation Trust | Transport & logistics | 1979 |
| THE EHO Consultant Ltd | Professional & scientific | 2025 |
| THE Farm Shop at Cranswick Limited | Wholesale & retail | 2013 |
| THE Fireworkers Limited | Wholesale & retail | 2009 |
| THE Graze Maids Ltd | Hospitality | 2025 |
| THE Hair Zone (Driffield) Limited | Other services | 2012 |
| THE Home Accessories Business Limited | Wholesale & retail | 2017 |
| THE Keddie Investment Company Ltd | Hospitality | 2014 |
| THE Liquid Lounge Hornsea Ltd | Other services | 2022 |
| THE Little Book Emporium Limited | Wholesale & retail | 2019 |
| THE Little White Dress Company (East Yorkshire) Ltd | Wholesale & retail | 2024 |
| THE Mill & Vine Events Ltd | Hospitality | 2025 |
| THE Mill & Vine Ltd | Hospitality | 2025 |
| THE Modern Draper Ltd | Administrative & support | 2017 |
| THE Office Co Group Limited | Financial services | 2023 |
| THE Old Star (Kilham) Limited | Hospitality | 2013 |
| THE Original Country Woodwork (Global) Limited | Construction | 2011 |
| THE Original Woodwork Company Limited | Manufacturing | 2008 |
| THE OWL House Art Studio Ltd | Extraterritorial | 2013 |
| THE Procurement Doctor Ltd | Professional & scientific | 2020 |
| THE Racing Emporium Limited | Arts & recreation | 2019 |
| THE Railway Quarter Holdings Limited | Financial services | 2022 |
| THE Robertson Practice Ltd | Health & social care | 2009 |
| THE Salon Driffield Ltd | Other services | 2011 |
| THE Scullery Bistro Ltd | Hospitality | 2018 |
| THE Significantly Beneficial Company Limited | Financial services | 2025 |
| THE Soper Group Limited | Manufacturing | 1997 |
| THE Spread Eagle (Driffield) Limited | Hospitality | 2013 |
| THE Stokes Jenkins Partnership Ltd | Professional & scientific | 2018 |
| THE Trade Centre (UK) Limited | Wholesale & retail | 2000 |
| THE Tree Walker Arborist Ltd | Agriculture & fishing | 2016 |
| THE Whichcote Group Limited | Hospitality | 2021 |
| THE Woof Inn Doggy Daycare Limited | Other services | 2021 |
| THE Woof Inn Ltd | Other services | 2019 |
| THE Worldwide Food Club Ltd | Manufacturing | 2017 |
| THE Yorkshire PEA Company Limited | Agriculture & fishing | 2009 |
| The-Whole-Shebang Ltd | Administrative & support | 2015 |
| Thirst Whitby Limited | Hospitality | 2016 |
| Thirteen Beers to Go Please Ltd | Hospitality | 2026 |
| Thompson's Engineering Ltd. | Manufacturing | 2014 |
| Thompsons Groundcare Limited | Other services | 2013 |
| Thorleys Limited | Manufacturing | 2008 |
| Thornbrook Moss Limited | Real estate | 2010 |
| Thornton Agencies Limited | Wholesale & retail | 2010 |
| Thornton-Varley Limited | Wholesale & retail | 2012 |
| Three 60 Capital Ltd | Construction | 2026 |
| Three 60 Construction (York) Ltd | Construction | 2025 |
| Thrifty Deals Ltd | Professional & scientific | 2024 |
| THU Thuy Limited | Other services | 2022 |
| Thurlow Garth Limited | Households | 1990 |
| TIB Construction Ltd | Construction | 2024 |
| TIC TOC Solutions Ltd | Professional & scientific | 2014 |
| Tiger Moth Flying Ltd | Administrative & support | 2022 |
| TIM Kelly Agricultural Services Limited | Manufacturing | 2006 |
| TO the Cloud!! Ltd | Professional & scientific | 2018 |
| Toddling East Yorkshire Limited | Administrative & support | 2017 |
| Tokenspire Cleaning Services Limited | Real estate | 2024 |
| Tokenspire Construction Limited | Construction | 1999 |
| Tokenspire Interiors & Furnishings Limited | Administrative & support | 2026 |
| Tokenspire Laundry Services Limited | Administrative & support | 2025 |
| Tom-Trans Services Ltd | Transport & logistics | 2024 |