| Snuzegb Ltd | Wholesale & retail | 2024 |
| SOA Designs Ltd | Professional & scientific | 2023 |
| Social Advertising Solutions Ltd | Professional & scientific | 2020 |
| Sofa & BED Centre Ireland Ltd | Wholesale & retail | 2024 |
| Sofa Hub Ltd | Wholesale & retail | 2023 |
| Sofa Majestic Ltd | Wholesale & retail | 2022 |
| Sofa Master Brother Ltd | Manufacturing | 2022 |
| Sofa World Ltd | Manufacturing | 2019 |
| Sofi Super Deals Ltd | Wholesale & retail | 2022 |
| Sofi's Cafe and Dessert Bar Ltd | Hospitality | 2026 |
| Soft Nights Ltd | Wholesale & retail | 2022 |
| Softbeds Ltd | Manufacturing | 2022 |
| Softsleep Ltd | Manufacturing | 2020 |
| Sognare Beds Ltd | Manufacturing | 2026 |
| Sohail Consultants Limited | Administrative & support | 2015 |
| Soks Installations Ltd | Construction | 2021 |
| Solace Beds Ltd | Manufacturing | 2024 |
| Solaire Blinds Limited | Wholesale & retail | 2016 |
| Solly Sports (Dewsbury) Limited | Wholesale & retail | 2015 |
| Soléne Aesthetics Ltd | Other services | 2025 |
| Something Property Ltd | Real estate | 2024 |
| South Asian Consortium Kirklees (Sack) | Other services | 2005 |
| South Street Dewsbury Ltd | Real estate | 2022 |
| Sova Beds Ltd | Manufacturing | 2025 |
| Sovera Living Ltd | Wholesale & retail | 2025 |
| Sovereign BED Company Limited | Manufacturing | 2022 |
| Sovereign Companies Ltd | Financial services | 2023 |
| Sovereign Live in Style Ltd | Manufacturing | 2013 |
| SP & H Ltd | Administrative & support | 2019 |
| SP Holdco 2022 Limited | Financial services | 2022 |
| SP Mortgages Ltd | Financial services | 2021 |
| SP Smile Ltd | Health & social care | 2022 |
| Sp&Co Ltd | Real estate | 2021 |
| Span Comfort Technology Ltd | Manufacturing | 2023 |
| Spartan Rehab Ltd | Health & social care | 2022 |
| Spectre Motor Company Ltd | Wholesale & retail | 2024 |
| Spedding Family Holdings Limited | Financial services | 2025 |
| Speed Arena UK Ltd | Arts & recreation | 2025 |
| Speed Petroleum (UK) Limited | Wholesale & retail | 2007 |
| Speedsoft Direct Ltd | Wholesale & retail | 2025 |
| Speedygo Ltd | Wholesale & retail | 2017 |
| Speights Engineering Ltd | Manufacturing | 2025 |
| Spen Building Services Ltd | Construction | 2004 |
| Spen Surveying Limited | Extraterritorial | 2024 |
| Spenborough Engineering EOT Limited | Financial services | 2025 |
| Spenborough Engineering Limited | Manufacturing | 1986 |
| Spenmotors Sales Ltd | Wholesale & retail | 2023 |
| Spike PUB Co Limited | Hospitality | 2018 |
| Spinners Fisheries Limited | Hospitality | 2025 |
| Spirited Software Development Limited | Information & communication | 2021 |
| Spirited Unions Ltd | Hospitality | 2025 |
| Splash & Dash Ltd | Wholesale & retail | 2024 |
| Splita Ltd | Professional & scientific | 2025 |
| Spring Stone Beds Ltd | Manufacturing | 2021 |
| Springer Transport Limited | Transport & logistics | 2022 |
| Springfield Flats Management Company Limited | Professional & scientific | 1990 |
| Springfield Garage MOT & Servicing Centre Limited | Wholesale & retail | 2024 |
| Springwell Flats Management Company Limited | Households | 1988 |
| Spudi Ltd | Hospitality | 2025 |
| Spunbond Limited | Wholesale & retail | 2019 |
| Square Cottage Ltd | Hospitality | 2026 |
| SR Legal Consultants Ltd | Professional & scientific | 2020 |
| SRD Foods UK Ltd | Hospitality | 2021 |
| SRE Hydrasteer (UK) Limited | Manufacturing | 2016 |
| SRS Investment Holdings Ltd | Administrative & support | 2025 |
| SS Mart Limited | Wholesale & retail | 2025 |
| SS Rainbow Services Limited | Administrative & support | 2015 |
| Ssgb Ltd | Financial services | 2024 |
| Ssks Holdings Group Ltd | Real estate | 2023 |
| SSM Clinical Solutions Ltd | Health & social care | 2019 |
| ST Locums Limited | Health & social care | 2016 |
| ST. John's Under 5'S Pre-School | Education | 2011 |
| Stables Commercial Vans Ltd | Wholesale & retail | 2025 |
| Stables Trade Centre Ltd | Wholesale & retail | 2025 |
| Stackdd Limited | Hospitality | 2026 |
| Staff Selection UK Ltd | Administrative & support | 2022 |
| Stalwart Industrial Group Limited | Wholesale & retail | 2011 |
| Standard Wool (UK) Limited | Manufacturing | 1962 |
| Standard Wool UK (Holdings) Limited | Manufacturing | 2004 |
| Star Embroidery Services Ltd | Manufacturing | 2020 |
| Star Estate (Dewsbury) Ltd | Real estate | 2024 |
| Star Petroleum UK Limited | Wholesale & retail | 2002 |
| Stargate Management Ltd | Professional & scientific | 2026 |
| Station Taxis Mirfield Ltd | Transport & logistics | 2025 |
| Station Vtec Ltd | Wholesale & retail | 2026 |
| Stay 'N' Play Ltd | Education | 2012 |
| Stayify Limited | Real estate | 2024 |
| Stears Logistics Ltd | Transport & logistics | 2023 |
| Steel Healthcare Ltd | Health & social care | 2022 |
| Steering Direct Ltd | Wholesale & retail | 2016 |
| Stefan V Construction Ltd | Construction | 2025 |
| Stellniche Ltd | Wholesale & retail | 2025 |
| Sterling Consultants PVT Limited | Professional & scientific | 2026 |
| Steve Blakeley Builders Limited | Construction | 2012 |
| Stockera Ltd | Wholesale & retail | 2026 |
| Stone and Meadow Lettings Ltd | Real estate | 2026 |
| Stone Center Limited | Administrative & support | 2023 |
| Stonebridge Consulting Ltd | Information & communication | 2025 |
| Stopdrop Tooling Limited | Wholesale & retail | 2007 |
| Stradale Corsa Ltd | Manufacturing | 2023 |