| Revoluter Limited | Extraterritorial | 2006 |
| Rhpg Group Ltd | Construction | 2024 |
| Rice and Sons Limited | Other services | 2005 |
| Richardd Limited | Wholesale & retail | 2025 |
| Riri Laser Clinic Ltd | Other services | 2020 |
| Riva Transport Limited | Transport & logistics | 2016 |
| Riverside Holdco Limited | Manufacturing | 2023 |
| Riverview Securities Limited | Real estate | 1997 |
| Robeys Ltd | Wholesale & retail | 2006 |
| Robinhud Limited | Construction | 2002 |
| Rockbolting Technology Limited | Mining & quarrying | 2004 |
| Rockport Property UK Limited | Real estate | 2005 |
| Rolls Laval Heat Exchangers Limited | Extraterritorial | 1994 |
| Rolls-Royce (Pension Trustees) Limited | Financial services | 1979 |
| Rolls-Royce India Limited | Professional & scientific | 1979 |
| Rolls-Royce Industries Limited | Professional & scientific | 1989 |
| Rolls-Royce International Limited | Professional & scientific | 1963 |
| Rolls-Royce Leasing Limited | Administrative & support | 1937 |
| Rolls-Royce Overseas Holdings Limited | Financial services | 1991 |
| Rolls-Royce Overseas Investments Limited | Administrative & support | 2000 |
| Rolls-Royce Power Engineering Limited | Manufacturing | 1977 |
| Rolls-Royce Total Care Services Limited | Transport & logistics | 1986 |
| RON Haslam Racing Academy Limited | Arts & recreation | 1995 |
| Roofstyle (NW) Limited | Wholesale & retail | 2007 |
| Root to Naturally Good Hair Limited | Other services | 2002 |
| Rosco Computer Systems Limited | Information & communication | 2001 |
| Ross Ceramics Limited | Manufacturing | 1988 |
| Rowcom Technical Services Limited | Other services | 2003 |
| Rykneld Bowling Club,Limited(The) | Arts & recreation | 1918 |
| S & K Carpenters Limited | Construction | 1997 |
| S & P Hewitt (Construction) Ltd | Real estate | 2003 |
| S & P Services (Longcliffe) Limited | Wholesale & retail | 2007 |
| S and D Special Bar Finishers Limited | | 1976 |
| S P Horobin Ltd | Water & waste | 2007 |
| S T Hoses Limited | Manufacturing | 2007 |
| S&J Engineering Services Ltd | Administrative & support | 2024 |
| S. Whitaker Ltd | Construction | 2007 |
| S.Anselm's School Limited | Education | 2025 |
| S.Ilayda Ltd | Hospitality | 2022 |
| S.J. Groves Building Contractors Ltd | Construction | 2002 |
| S.R. Barlow Decorating Limited | Construction | 2007 |
| Salaries Limited | Administrative & support | 2000 |
| Salcare Ltd | Wholesale & retail | 1997 |
| Salcs Ltd | Information & communication | 2024 |
| Salmon Management Group Limited | Professional & scientific | 1999 |
| Saltergate Physiotherapy Limited | Health & social care | 2007 |
| Sanam Tandoori Restaurant Limited | Hospitality | 2002 |
| Sandyford Farm Cattery & Kennels Limited | Other services | 2002 |
| Sawarn & Co. Ltd | Professional & scientific | 2004 |
| SB Cctv Limited | Construction | 2005 |
| SBS Build Limited | Construction | 2004 |
| SC Johnson Professional Group Limited | Administrative & support | 2003 |
| Schools OUT Club (Derby) Limited | Health & social care | 2006 |
| Scott Plumbing & Heating Ltd | Construction | 2011 |
| Screw Mill Castings Limited | Wholesale & retail | 1987 |
| Sculpture Works Limited | Administrative & support | 2004 |
| Serverside Consulting Limited | Professional & scientific | 2005 |
| Service Exclusive Ltd. | Information & communication | 2002 |
| Service Home Limited | Education | 1993 |
| SG Shopfitting Limited | Construction | 1999 |
| Shaftsbury Education & Training Centre | Other services | 2007 |
| Shakespeare's (Whitwell) Limited | | 1950 |
| Sheltone Village Management Company Limited | Households | 2020 |
| Shenpar Products Limited | Wholesale & retail | 1980 |
| Shepherd Road Apartments Management Company Limited | Households | 2022 |
| Shergill's Off-Licence Limited | Wholesale & retail | 2002 |
| Shire Software Ltd. | Information & communication | 1998 |
| Shiredale Limited | Professional & scientific | 2006 |
| Shires Crane Hire Limited | Construction | 2003 |
| Sideflow Computing Limited | Professional & scientific | 1990 |
| Sign Systems (Holdings) Ltd | Professional & scientific | 2016 |
| Sign Systems (UK) Limited | Manufacturing | 2006 |
| Sigston Consultancy Ltd | Information & communication | 2004 |
| Sil-Brite Limited | Construction | 1982 |
| Silver Willow Management Limited | Households | 2003 |
| Silverman & SON Limited | Wholesale & retail | 2007 |
| Simjo Limited | Other services | 1985 |
| Simon CNC Services Limited | Administrative & support | 1999 |
| Simon James Kitchens Limited | Construction | 2003 |
| Simply Thai (U.K.) Limited | Hospitality | 2003 |
| Simulator Technical Services Limited | Manufacturing | 2003 |
| SJC Installations Limited | Construction | 2006 |
| Skate Nottingham C.I.C. | Professional & scientific | 2017 |
| Sky Bridging Limited | Financial services | 2018 |
| Slimlines Limited | Professional & scientific | 2005 |
| Smart Engineering (UK) Limited | Manufacturing | 2007 |
| Smartware Ltd | Wholesale & retail | 2006 |
| Smith of Derby Group Limited | Manufacturing | 1914 |
| Smith of Derby Limited | Manufacturing | 1978 |
| Smith-Guarino Trading Limited | Other services | 2006 |
| Smithy Wood Gate (Dodworth) Management Company Limited | Households | 2025 |
| Soar House Limited | Professional & scientific | 2005 |
| Soft Orange Ltd | Information & communication | 2017 |
| Software Fusion Limited | Information & communication | 1995 |
| Sound Monkeys Ltd | Manufacturing | 2007 |
| Sounello Limited | Wholesale & retail | 2007 |
| South Eastern Train Maintenance Limited | Extraterritorial | 1997 |
| South Winchester Freehold Lodges Limited | Real estate | 2021 |
| Sparrow Investments Ltd | Real estate | 2003 |
| Speedy Auto Spares Limited | Other services | 2001 |