| Easy Drive Derby Ltd | Education | 2022 |
| Easy Finish Ltd | Construction | 2024 |
| Easy Move of Derby Limited | Transport & logistics | 2012 |
| Easy Relocations Limited | Real estate | 2013 |
| Easy Software Solutions Ltd | Information & communication | 2026 |
| Easy Tigers Indoor Play Centres Limited | Arts & recreation | 2004 |
| Easyglide (Derby) Limited | Wholesale & retail | 2010 |
| Easylockup Ltd | Other services | 2014 |
| Easyshop Derby Limited | Wholesale & retail | 2026 |
| Easytiger Platinum Limited | Construction | 2011 |
| EAT My Cookie Limited | Hospitality | 2020 |
| EAT My Waffle Limited | Hospitality | 2020 |
| Eaton Consulting Limited | Construction | 2021 |
| Eaton Fayre Ltd | Wholesale & retail | 2014 |
| Eaton Fire & Security Ltd | Construction | 2017 |
| Eaton Gate Gaming Limited | Professional & scientific | 2015 |
| Eaton Search Limited | Administrative & support | 2004 |
| Eaton Sweeney Ltd | Wholesale & retail | 2019 |
| Eaton View Limited | Administrative & support | 2018 |
| Eaton-Drafeld Limited | Professional & scientific | 1980 |
| Eaton-Williams Service Limited | Energy | 2022 |
| Eazy Stay Properties Ltd | Households | 2025 |
| Ebenezer(Stone of Help) Ltd | Health & social care | 2013 |
| Eberle Business Solutions Ltd | Administrative & support | 2012 |
| EBH Holdings Ltd | Real estate | 2025 |
| Ebierecoaching Ltd | Education | 2025 |
| Ebina Limited | Hospitality | 2003 |
| EBM Logistics Ltd | Wholesale & retail | 2022 |
| Ebony Property Ltd | Real estate | 2025 |
| Ec&I Systems Limited | Professional & scientific | 2022 |
| ECB (Water Solutions ) Ltd | Professional & scientific | 2010 |
| Eccentric Coder Limited | Information & communication | 2016 |
| Ecclesbourne Plant Centre Limited | Real estate | 2011 |
| Echelon Digital Group Ltd | Professional & scientific | 2025 |
| Echo Hearing Solutions Ltd | Wholesale & retail | 2026 |
| Eclipse Enterprise Consulting Limited | Professional & scientific | 2010 |
| Ecm.London Ltd | Wholesale & retail | 2022 |
| Eco Air Control Ltd | Energy | 2016 |
| Eco Air Facilities Management Limited | Administrative & support | 2019 |
| Eco Blue Cleaning Ltd | Administrative & support | 2016 |
| Eco Cycleing Ltd | Wholesale & retail | 2024 |
| Eco Energy Storage Systems Ltd | Wholesale & retail | 2022 |
| Eco Express Hire Ltd | Administrative & support | 2021 |
| Eco Green Midland Ltd | Construction | 2026 |
| Eco Healthcare Ltd | Health & social care | 2023 |
| Eco Home Hub Ltd | Wholesale & retail | 2023 |
| Eco Pest & Wildlife Management Services Ltd | Professional & scientific | 2025 |
| Eco Solar Regeneration Ltd | Administrative & support | 2021 |
| Eco Switch Improvements Ltd | Construction | 2022 |
| Eco Tax Holdings Ltd | Agriculture & fishing | 2021 |
| Eco Tax Investments Ltd | Administrative & support | 2021 |
| Eco-Asphalt Supplies Limited | Extraterritorial | 2021 |
| Ecoblaq Disposal Systems Ltd | Water & waste | 2025 |
| Ecocycle SSA Ltd | Wholesale & retail | 2025 |
| Ecofleet Cleaning Solutions Ltd | Manufacturing | 2016 |
| Ecofuture Cleaning Limited | Administrative & support | 2025 |
| Ecom BEE Ltd | Wholesale & retail | 2017 |
| Ecom Village Ltd | Wholesale & retail | 2020 |
| Ecombydube Ltd | Wholesale & retail | 2023 |
| Economit Limited | Information & communication | 2011 |
| Ecopro (Midlands) Limited | Construction | 2024 |
| Ecoratio Limited | Wholesale & retail | 2016 |
| Ecotect Ltd | Wholesale & retail | 2020 |
| Ecotherm Care Limited | Professional & scientific | 2019 |
| Ecowise Utilities Limited | Professional & scientific | 2025 |
| Ecru (Eco) Ltd | Agriculture & fishing | 2021 |
| Ecsol Limited | Professional & scientific | 2007 |
| ECW Consulting Ltd | Professional & scientific | 2012 |
| ED Postlethwaite Limited | Financial services | 2024 |
| ED Recycling Ltd | Water & waste | 2026 |
| Ed&Gj Limited | Financial services | 2024 |
| Edbro AG Serv Limited | Wholesale & retail | 2011 |
| Edden Developments Limited | Construction | 2026 |
| Edee Limited | Wholesale & retail | 2020 |
| Eden Art & Events Ltd | Professional & scientific | 2023 |
| Eden Beauty (Derby) Limited | Other services | 2017 |
| Eden Clothing Limited | Wholesale & retail | 2002 |
| Eden House Group Limited | Construction | 2017 |
| Eden Lodge Care Home Ltd | Health & social care | 2019 |
| Eden Tyres & Servicing Limited | Extraterritorial | 2025 |
| Edenkyte Prestige Ltd | Wholesale & retail | 2022 |
| Edenkyte Property Ltd | Real estate | 2022 |
| Edex Ltd | Transport & logistics | 2015 |
| Edgar Property Company Limited | Real estate | 2013 |
| Edge Manor Limited | Real estate | 2023 |
| Edge Performance Club Ltd | Information & communication | 2025 |
| Edgelime Limited | Real estate | 1993 |
| Edgell Accounts & Tax Services Limited | Professional & scientific | 2019 |
| Edgewater Motors Ltd | Wholesale & retail | 2022 |
| Edildoctor Two Ltd | Construction | 2020 |
| Edina Burns Limited | Financial services | 2016 |
| Edithgun.Org Ltd | Professional & scientific | 2025 |
| EDJ Investments Ltd | Real estate | 2022 |
| Edjane Cleaning and Valeting Ltd | Administrative & support | 2021 |
| Edjprop 1 Ltd | Real estate | 2026 |
| Edmack Ltd | Transport & logistics | 2019 |
| Edobros Limited | Information & communication | 2025 |
| Edon Design Ltd | Professional & scientific | 2023 |
| Edosh Consultancy Ltd | Health & social care | 2022 |
| Educate Elevate Ltd | Education | 2021 |