| Derbyshire County Football Association Limited | Arts & recreation | 2000 |
| Derbyshire County Golf Limited | Arts & recreation | 2017 |
| Derbyshire Cricket Foundation Limited | Arts & recreation | 2013 |
| Derbyshire Dales Demolition Limited | Construction | 2020 |
| Derbyshire Decorators Limited | Construction | 1985 |
| Derbyshire Developments Ltd | Real estate | 2023 |
| Derbyshire Driveways Limited | Construction | 2025 |
| Derbyshire Electrical Services Limited | Construction | 2021 |
| Derbyshire Elite Car Sales Limited | Wholesale & retail | 2021 |
| Derbyshire Fascias Limited | Construction | 2019 |
| Derbyshire Flooring Contractors Limited | Construction | 1982 |
| Derbyshire Garage Doors and Gates Limited | Construction | 2015 |
| Derbyshire Homecare Limited | Health & social care | 2001 |
| Derbyshire Hong Kong Community Interest Company | Professional & scientific | 2021 |
| Derbyshire Igloos Ltd | Administrative & support | 2022 |
| Derbyshire Independent Financial Services Limited | Financial services | 2017 |
| Derbyshire Industrial Cleaners Limited | Administrative & support | 2022 |
| Derbyshire Institute of Sport C.I.C. | Arts & recreation | 2017 |
| Derbyshire IT Services Ltd | Information & communication | 2020 |
| Derbyshire Lgbt+ Ltd | Education | 1999 |
| Derbyshire Maid Services Ltd | Health & social care | 2025 |
| Derbyshire Mind | Health & social care | 1994 |
| Derbyshire Mortgage Services Ltd | Financial services | 2005 |
| Derbyshire OFF Grid Ltd | Agriculture & fishing | 2022 |
| Derbyshire Peaks Management Services Ltd | Real estate | 2012 |
| Derbyshire Prestige Cars (UK) Limited | Wholesale & retail | 2015 |
| Derbyshire Property Maintenance Limited | Administrative & support | 2008 |
| Derbyshire Property Services Limited | Households | 2015 |
| Derbyshire Removal Service Ltd | Transport & logistics | 2024 |
| Derbyshire Renovations Ltd | Real estate | 2021 |
| Derbyshire Security Equipment Limited | Wholesale & retail | 1984 |
| Derbyshire Serenity Foundation C.I.C. | Administrative & support | 2025 |
| Derbyshire Smile Care Ltd | Health & social care | 2018 |
| Derbyshire Student Residences Limited | Real estate | 1995 |
| Derbyshire Tamil Organisation CIC | Education | 2024 |
| Derbyshire Tax Services Ltd | Professional & scientific | 2010 |
| Derbyshire Telecom Services Ltd | Information & communication | 2008 |
| Derbyshire Tennis Limited | Arts & recreation | 2024 |
| Derbyshire Tree Services Ltd | Administrative & support | 2017 |
| Derbyshires Finest Limited | Extraterritorial | 2007 |
| Derbysostyres Ltd | Wholesale & retail | 2026 |
| Derby’S Beautyspot Limited | Wholesale & retail | 2018 |
| Derek Latham & Co. Limited | Professional & scientific | 1987 |
| Derhab Ltd | Health & social care | 2020 |
| Derivatives Legal Solutions Limited | Professional & scientific | 2020 |
| Dermodocs Ltd | Wholesale & retail | 2019 |
| Dernek Ltd | Information & communication | 2018 |
| Derrada Limited | Financial services | 2020 |
| Derve Limited | Agriculture & fishing | 2025 |
| Derventio Catering Ltd | Hospitality | 2024 |
| Derventio Design Ltd | Wholesale & retail | 2004 |
| Derventio Education Limited | Information & communication | 2009 |
| Derventio Housing Trust CIC | Real estate | 2006 |
| Derventio Solutions Limited | Information & communication | 2006 |
| Derventiouk Limited | Transport & logistics | 2009 |
| Derwen Assets Ltd | Real estate | 2025 |
| Derwent Associates (Derby) Limited | Professional & scientific | 2016 |
| Derwent Blinds Limited | Wholesale & retail | 2002 |
| Derwent Bridges Limited | Real estate | 2001 |
| Derwent Building & Design Limited | Construction | 2000 |
| Derwent Building Ltd | Construction | 2024 |
| Derwent Corporate Services Limited | Professional & scientific | 2025 |
| Derwent Ducting Limited | Construction | 2017 |
| Derwent Emporium Limited | Wholesale & retail | 2024 |
| Derwent Energy Ltd | Construction | 2025 |
| Derwent Fabrication & Welding Ltd | Manufacturing | 2024 |
| Derwent Facilities Ltd | Other services | 2017 |
| Derwent Facilities Management Limited | Administrative & support | 2010 |
| Derwent Fencing Limited | Construction | 2004 |
| Derwent Financial Planning Limited | Professional & scientific | 2017 |
| Derwent Gardens Limited | Households | 2006 |
| Derwent Gymnastics Academy CIC | Arts & recreation | 2019 |
| Derwent Information Services Limited | Information & communication | 2018 |
| Derwent Investment Propco Limited | Real estate | 2020 |
| Derwent James Ltd | Professional & scientific | 2009 |
| Derwent Motors Limited | Wholesale & retail | 2021 |
| Derwent Patterns & Models Ltd | Manufacturing | 2006 |
| Derwent Planning Ltd | Professional & scientific | 2026 |
| Derwent Properties (UK) Limited | Real estate | 2012 |
| Derwent Safety Centre Limited | Other services | 2003 |
| Derwent Services (Derby) Ltd | Manufacturing | 2019 |
| Derwent Stepping Stones Nursery and Community Training Centre | Education | 1993 |
| Derwent Training Consultants Limited | Administrative & support | 2010 |
| Derwent Tuning Limited | Wholesale & retail | 2021 |
| Derwent Valley Butchery Ltd | Wholesale & retail | 2019 |
| Derwent Valley Tooling Limited | Manufacturing | 2002 |
| Derwent Vally Ltd | Wholesale & retail | 2026 |
| Derwent Waste Management Limited | Water & waste | 2005 |
| Derwent Weighing Limited | Manufacturing | 2006 |
| Derwentside Management Company Ltd | Households | 2020 |
| DES19N Limited | Information & communication | 2008 |
| DES19NCOR Limited | Professional & scientific | 2012 |
| Desi Karahi Midland Ltd | Hospitality | 2025 |
| Desi Munch Limited | Hospitality | 2026 |
| Desi Sweet Centre Derby Ltd | Wholesale & retail | 2022 |
| Design & Analysis Consultants Limited | Professional & scientific | 2013 |
| Design 44 Limited | Wholesale & retail | 2019 |
| Design at Nine Studio Ltd | Arts & recreation | 2026 |
| Design Carbon Ltd | Professional & scientific | 2022 |
| Design Einstien Ltd | Information & communication | 2021 |