| Dare Consulting Limited | Professional & scientific | 2017 |
| Darewhaps Limited | Wholesale & retail | 2025 |
| Dargo Driver Ltd | Transport & logistics | 2019 |
| Darin 15 Limited | Other services | 2025 |
| Darin Car Sales Limited | Wholesale & retail | 2025 |
| Dario Pizzi Design Ltd | Administrative & support | 2022 |
| Dark Arts Collective Ltd | Arts & recreation | 2022 |
| Dark Developments Limited | Real estate | 2005 |
| Dark Horse Consulting Services Limited | Information & communication | 2023 |
| Dark Kitchen Ltd | Hospitality | 2024 |
| Dark Skies Ensemble Ltd | Arts & recreation | 2023 |
| Darkcat Ltd | Information & communication | 2012 |
| Darkwave Limited | Information & communication | 2023 |
| Darley Abbey Construction Limited | Wholesale & retail | 2011 |
| Darley Abbey Distillery Limited | Wholesale & retail | 2022 |
| Darley Abbey Electrical Limited | Construction | 2014 |
| Darley ABC Ltd | Other services | 2024 |
| Darley Cabs Matlock Limited | Transport & logistics | 2025 |
| Darley Classics Period Mouldings Limited | Construction | 2009 |
| Darley Consultancy Limited | Extraterritorial | 2022 |
| Darley Property Services Ltd | Construction | 2025 |
| Darley Services Limited | Manufacturing | 2019 |
| Darleyfield Properties Limited | Professional & scientific | 2013 |
| Darling Eyecare Ltd | Health & social care | 2010 |
| Darlinghurst Developments Limited | Real estate | 2025 |
| Darne Mews (Hulland Ward) Management Company Limited | Households | 2017 |
| Darren Reid Paintings Limited | Arts & recreation | 2017 |
| Darrow Paint Services Limited | Construction | 2017 |
| Darul Arqam Bookstore Ltd | Wholesale & retail | 2024 |
| Darwin Place Management Company Limited | Households | 2003 |
| Dash Courier Services Derby Ltd | Wholesale & retail | 2023 |
| Dash Information Systems Limited | Information & communication | 1999 |
| Dashine Technology Limited | Wholesale & retail | 2022 |
| Dashing Distribution Software Limited | Information & communication | 2020 |
| Dashlogs UK Limited | Wholesale & retail | 2025 |
| Dashly Limited | Information & communication | 2015 |
| Dastan Traders Ltd | Wholesale & retail | 2025 |
| Data Care Services Limited | Administrative & support | 2019 |
| Data Clarity Limited | Information & communication | 2011 |
| Data Mechanical & Building Services Limited | Construction | 1997 |
| Data Options Ltd | Information & communication | 2025 |
| Data Solutions Limited | Hospitality | 1994 |
| Data Strategy Alliance Ltd | Information & communication | 2023 |
| Datachk Ltd | Information & communication | 2025 |
| Datactor IT Solutions Limited | Transport & logistics | 2019 |
| Datagiants Limited | Information & communication | 2025 |
| Dataharbor Insights Ltd | Information & communication | 2023 |
| Datanovel Limited | Information & communication | 2025 |
| Datapath Group Limited | Professional & scientific | 2011 |
| Datapath Limited | Manufacturing | 1982 |
| Datasculptz Solutions Ltd | Information & communication | 2023 |
| Datconet Ltd | Information & communication | 2024 |
| Datom Plastering Contractors Ltd | Construction | 2015 |
| Datum Holdings 2009 Limited | Financial services | 2009 |
| Datum Pattern & Model Makers Limited | Manufacturing | 2001 |
| Datumnilc Ltd | Information & communication | 2014 |
| Dave Horton Consulting Limited | Professional & scientific | 2020 |
| Dave Woodward Building Services Ltd | Construction | 2019 |
| Davenport Paper Co Limited | Wholesale & retail | 1986 |
| David Adams Joinery Limited | Construction | 2004 |
| David and Collins Limited | Administrative & support | 2025 |
| David Barber (O.H.) Ltd | Health & social care | 2015 |
| David Barker Contractors Limited | Construction | 1975 |
| David Brown Architecture Ltd | Professional & scientific | 2016 |
| David Brown Property Management Limited | Real estate | 2013 |
| David Clark Engineering Limited | Manufacturing | 2017 |
| David Cliff Limited | Agriculture & fishing | 1973 |
| David Gordon Limited | Manufacturing | 2000 |
| David Kirk & Associates Limited | Professional & scientific | 1981 |
| David Mason QS (Derby) Limited | Professional & scientific | 2020 |
| David Naylor Transport Limited | Transport & logistics | 2000 |
| David Prince (Agricultural) Limited | Agriculture & fishing | 2004 |
| David RAY (Sales) Limited | Wholesale & retail | 2005 |
| David RAY Commercials Limited | Wholesale & retail | 2002 |
| David RAY Limited | Wholesale & retail | 2005 |
| David Rouse Financial Consultancy Limited | Financial services | 1999 |
| David Sebastian Limited | Other services | 2013 |
| David Sebastian Pubs Ltd | Hospitality | 2025 |
| David Shields Ltd | Real estate | 2017 |
| David Smith Aviation Consulting Ltd | Professional & scientific | 2017 |
| David W. Fearn Decorators Limited | Construction | 2003 |
| David Wilkinson Consulting Limited | Professional & scientific | 2015 |
| David's 30 Ltd | Arts & recreation | 2024 |
| Davidson Property Connexions Ltd | Real estate | 2019 |
| Davidson Property Sourcing Ltd | Real estate | 2019 |
| Davidson-Richards (International) Limited | Information & communication | 1977 |
| Davidson-Richards Holdco 1 Limited | Financial services | 2025 |
| Davidson-Richards Holdings Limited | Information & communication | 2009 |
| Davinchi Floor Tools Ltd | Manufacturing | 2023 |
| Davinchi Holdings Ltd | Financial services | 2021 |
| Davis & Co Properties Ltd | Real estate | 2022 |
| Davis Accountants Limited | Professional & scientific | 2015 |
| Davis Derby Holdings Limited | Manufacturing | 2008 |
| Davis Derby Limited | Manufacturing | 1992 |
| Davis Therapies Limited | Health & social care | 2023 |
| Davison Property (Derby) Ltd | Real estate | 2023 |
| Davison Property Limited | Real estate | 2007 |
| Davlyn Construction Limited | Construction | 2003 |
| Davlyn Group Limited | Financial services | 2008 |
| Davlyn Ltd | Professional & scientific | 2008 |