| Stohos Properties Ltd | Real estate | 2025 |
| Stojak Law Limited | Professional & scientific | 2026 |
| Stomp Property Limited | Real estate | 2024 |
| Stone 75 Ltd | Financial services | 2025 |
| Stone Building Services (Derby) Ltd | Construction | 2018 |
| Stone Business Development Ltd | Professional & scientific | 2018 |
| Stone Drives & Landscapes Ltd | Professional & scientific | 2020 |
| Stone Exterior Cleaning Services Ltd | Administrative & support | 2025 |
| Stone Hill Trustees Limited | Professional & scientific | 1968 |
| Stone O' Help UK Limited | Real estate | 2021 |
| Stone of Help Management Limited | Other services | 2023 |
| Stone PAT Testing Ltd | Professional & scientific | 2024 |
| Stone PIT Property Limited | Real estate | 2018 |
| Stone Property Investments Limited | Extraterritorial | 2001 |
| Stone Road Corporate Finance Limited | Professional & scientific | 2004 |
| Stone Spring Limited | Construction | 2020 |
| Stonelink Investment Management Limited | Real estate | 1996 |
| Stonemile Investments Limited | Extraterritorial | 2010 |
| Stonemile Limited | Real estate | 2010 |
| Stones Interiors Limited | Manufacturing | 2022 |
| Stones Restaurant Ltd | Hospitality | 2014 |
| STONES4HOMES Ltd | Wholesale & retail | 2008 |
| Stonesdale Ltd | Administrative & support | 2019 |
| Stoneshore Ltd | Real estate | 2025 |
| Stoney Grabs Ltd | Real estate | 2025 |
| Stored Energy Technology Limited | Manufacturing | 1998 |
| Storfa Ltd | Professional & scientific | 2005 |
| Storm Engineering (Midlands) Limited | Wholesale & retail | 2018 |
| Storm Financial Consulting Ltd | Professional & scientific | 2023 |
| Storm Legal Limited | Professional & scientific | 2020 |
| Storm Research Limited | Professional & scientific | 2009 |
| Storm Water Systems Limited | Construction | 2011 |
| Stormproof Property Maintenance Ltd | Construction | 2013 |
| Stormshield Windows Limited | Construction | 2011 |
| Storybook Holdings Limited | Financial services | 2025 |
| Storybook Media Consultancy Ltd | Manufacturing | 2025 |
| Storybook Properties Limited | Real estate | 2025 |
| Stox Ltd | Wholesale & retail | 2026 |
| Stprojects Limited | Construction | 2014 |
| Strand Nine (Derby) Limited | Real estate | 2026 |
| Strand Retail Limited | Transport & logistics | 2007 |
| Strange & Co Advisory Ltd | Professional & scientific | 2025 |
| Strata Real Estate Consulting LLP | | 2009 |
| Strata Real Estate Limited | Real estate | 2011 |
| Strataline Ltd | Transport & logistics | 2025 |
| Strataway Holdings Limited | Financial services | 2026 |
| Strategic Life Limited | Administrative & support | 2021 |
| Strategic Placements Limited | Administrative & support | 1999 |
| Strategic Pulse Ltd | Professional & scientific | 2023 |
| Strategic Solutions International Limited | Professional & scientific | 2009 |
| Strategy Five Limited | Professional & scientific | 2019 |
| Strategy LAB Ltd | Professional & scientific | 2020 |
| Strategy Shift Ltd | Professional & scientific | 2020 |
| Stratford Property Group Limited | Construction | 2025 |
| Stratigence Consulting Ltd | Professional & scientific | 2024 |
| Stratleaf Ltd | Wholesale & retail | 2016 |
| Stratos Enforcement Ltd | Administrative & support | 2026 |
| Strattons of Bournemouth Used Car Sales Ltd | Wholesale & retail | 2018 |
| Straughan Properties Ltd | Real estate | 2016 |
| Strauss Structural Design Ltd | Professional & scientific | 2020 |
| Strauss Sustainables CIC | Construction | 2020 |
| Strawberry Burst Limited | Information & communication | 2014 |
| Strawberry House Interiors Limited | Wholesale & retail | 2009 |
| Strawberry Mews (Yatton) Management Company Limited | Households | 2025 |
| Strawdog Limited | Financial services | 2008 |
| Strawdog Productions Ltd | Information & communication | 2012 |
| Strawdog Publishing Limited | Information & communication | 2005 |
| Strawdog Studios Limited | Information & communication | 2003 |
| Streaming Services Limited | Information & communication | 2026 |
| Streamline Logistics Limited | Transport & logistics | 2016 |
| Street Champs Ltd | Wholesale & retail | 2026 |
| Street Farm Day Nursery Limited | Education | 2003 |
| Street Soccer Derby Limited | Arts & recreation | 2024 |
| Street Whyze Project CIC | Education | 2022 |
| Streethay Residents Management Company Limited | Households | 2017 |
| Streets Ahead Mortgages Ltd | Financial services | 2019 |
| Stress Free IT Solutions Ltd | Information & communication | 2022 |
| Stress MAN Limited | Information & communication | 2011 |
| Strettea Holdings Limited | Professional & scientific | 2017 |
| Strettea Independent Trustees Limited | Professional & scientific | 2014 |
| Stretton Hall Development Company Ltd | Construction | 2013 |
| Stretton Legal Services Ltd | Professional & scientific | 2021 |
| Stride Health Ltd | Health & social care | 2018 |
| Strikepath Limited | Information & communication | 2025 |
| Strimon Solutions Limited | Professional & scientific | 2019 |
| String Laminating Ltd | Manufacturing | 2023 |
| Stringle Human Capital Management and Consulting Limited | Professional & scientific | 2024 |
| Strong Rail Solutions Ltd | Professional & scientific | 2026 |
| Strover Enterprises Ltd | Real estate | 2019 |
| Strovers Enterprises Holdco Limited | Financial services | 2021 |
| Structural Interior Installations Ltd | Professional & scientific | 2022 |
| Structural Properties Limited | Financial services | 2008 |
| Strumis Ltd | Information & communication | 1986 |
| Struservices Limited | Professional & scientific | 2013 |
| Strutt Arms Limited | Hospitality | 2015 |
| Strutts Park House Residents Association Limited | Other services | 1998 |
| Strutts Salon Ltd | Administrative & support | 2016 |
| STS Flooring Ltd | Other services | 2025 |
| Stuart Clarke Limited | Financial services | 2007 |
| Stuart Fabrications Limited | Professional & scientific | 2019 |