| PW Marine Limited | Manufacturing | 2009 |
| PWT Engineering Ltd | Professional & scientific | 2022 |
| PWT Procurement Ltd | Professional & scientific | 2017 |
| PY Trades Ltd | Professional & scientific | 2022 |
| Q & E Nails Ltd | Other services | 2023 |
| Q Corporation Ltd | Education | 2019 |
| Q7ESTATES Limited | Real estate | 2018 |
| Q9 Cladding Solutions Holdings Limited | Financial services | 2024 |
| Q9 Cladding Solutions Ltd | Construction | 2011 |
| Qeyam AL Jazeera Ltd | Wholesale & retail | 2025 |
| QL Development Ltd | Construction | 2021 |
| QL Property Group Ltd | Real estate | 2020 |
| QP Hair and Beauty Ltd | Other services | 2020 |
| QSR Cleaning Specialists Ltd | Water & waste | 2016 |
| Quadlis Project Management Ltd | Construction | 2015 |
| Quadrant (Darlington) Limited | Education | 1993 |
| Quadventures Ltd | Extraterritorial | 2010 |
| Quaker (Darlington) Management Co. Limited | Households | 1996 |
| Quaker Furniture Ltd | Wholesale & retail | 2024 |
| Quality Catering Co NE Ltd | Hospitality | 2024 |
| Quality Cleaning Services (Northern) Limited | Administrative & support | 1995 |
| Quality Foods NE Limited | Hospitality | 2024 |
| Quality Sports Supplements Ltd | Wholesale & retail | 2011 |
| Quanfluence Limited | Information & communication | 2023 |
| Quantum Contract Management Limited | Professional & scientific | 2011 |
| Quay Solutions NE Ltd | Professional & scientific | 2016 |
| Queribus Ltd | Financial services | 2011 |
| Quick & Easy Projects Ltd | Construction | 2015 |
| Quickd Limited | Extraterritorial | 2018 |
| Quickway Transport Limited | Transport & logistics | 2022 |
| Quillnary Press Limited | Information & communication | 2026 |
| Quint Aura Clothing Ltd | Wholesale & retail | 2026 |
| R & V Dawson Ltd | Hospitality | 2021 |
| R Cosgrove Limited | Professional & scientific | 2018 |
| R E Projects Ltd | Extraterritorial | 2018 |
| R Langley & Sons Ltd | Construction | 2008 |
| R M Harrison Sales | Professional & scientific | 2013 |
| R M Plant & Commercials Ltd | Wholesale & retail | 2019 |
| R M Properties (NE) Ltd | Real estate | 2023 |
| R Mochrie Limited | Administrative & support | 2021 |
| R N Commercials and Agricultural Ltd | Wholesale & retail | 2021 |
| R R Commercials Ltd | Wholesale & retail | 2011 |
| R V S Group Limited | Manufacturing | 1982 |
| R&J Scarr Ltd | Administrative & support | 2025 |
| R. Raymund Building Ltd | Construction | 2008 |
| R.Bland Limited | Construction | 1961 |
| R.Rana Ltd | Professional & scientific | 2020 |
| R2NETSOLUTIONS Limited | Extraterritorial | 2024 |
| R3:SET CIC | Education | 2026 |
| R4LOCCUPATIONALHEALTH Ltd | Health & social care | 2025 |
| RA Buchanan Logistics Ltd | Transport & logistics | 2025 |
| RA Kitchens Ltd | Construction | 2018 |
| Rabs Automotive Ltd | Wholesale & retail | 2018 |
| Raby Farms Shropshire LLP | | 2020 |
| Raby Homes Limited | Construction | 2025 |
| Rachael Carmichael Limited | Other services | 2016 |
| Rachel Taylor Interior Design Limited | Professional & scientific | 2021 |
| Rachel Wells Food Limited | Hospitality | 2017 |
| Radgie Group Limited | Hospitality | 2026 |
| Radius Technology Solutions Limited | Information & communication | 2023 |
| Rafter North Ltd | Wholesale & retail | 2025 |
| Rage & Love Ltd | Wholesale & retail | 2023 |
| Rainbow Adventures Limited | Health & social care | 2021 |
| Rainbow Keys Ltd | Real estate | 2024 |
| Rainbow Unicorn IP Ltd | Real estate | 2019 |
| Rairza Ltd | Wholesale & retail | 2024 |
| Ralhee Limited | Other services | 2023 |
| Ramrat Transport Ltd | Transport & logistics | 2025 |
| Ramsay Plant Sales Limited | Wholesale & retail | 2009 |
| Ramsay's Cleaner Cookers Limited | Other services | 2024 |
| Randhiv Limited | Hospitality | 2017 |
| Rank First SEO Ltd | Professional & scientific | 2025 |
| Ranson Roofing and Building Ltd | Administrative & support | 2018 |
| Rapid Home Buyers Ltd | Real estate | 2017 |
| Rapids Waste Removal Services Ltd | Water & waste | 2026 |
| Rapta Ltd | Construction | 2024 |
| RAT Barrow UK Limited | Wholesale & retail | 2023 |
| Ratcliff and Roper (Printers) Limited | Manufacturing | 1946 |
| Rated Conversions Ltd | Manufacturing | 2016 |
| Rated Holdings (North East) Ltd | Real estate | 2020 |
| Rated Holdings Ltd | Real estate | 2020 |
| Rated Land Limited | Real estate | 2021 |
| Rated Maintenance Ltd | Construction | 2014 |
| Rauwan Ltd. | Arts & recreation | 2015 |
| Ravenhill Technology Ltd | Other services | 2001 |
| Ravensdale Projects & Engineered Solutions Ltd | Professional & scientific | 2026 |
| Ravensworth Property Limited | Extraterritorial | 2009 |
| RAW Digital Training Ltd | Professional & scientific | 2013 |
| RAW Inspiration Ltd | Education | 2023 |
| RAY & Company(Hairdressers Sundries Men)Limited | Wholesale & retail | 1946 |
| Raydaleside Management Company Limited | Households | 2002 |
| Rayson Properties Ltd | Real estate | 2019 |
| RB Wade Groundworks Ltd | Construction | 2020 |
| Rbjb Ltd | Manufacturing | 2018 |
| RBT Construction (Plant) Limited | Construction | 2017 |
| RCC Consulting Ltd | Information & communication | 2019 |
| RCO Ltd | Real estate | 2014 |
| RCO Property Ltd | Real estate | 2024 |
| RCT Consulting Ltd | Professional & scientific | 2023 |
| RD Rail Solutions Ltd | Transport & logistics | 2019 |