| E-Type Fabs NO 1 Ltd | Administrative & support | 2022 |
| E-Type Fabs NO 10 Ltd | Administrative & support | 2022 |
| E-Type Fabs NO 11 Ltd | Administrative & support | 2022 |
| E-Type Fabs NO 12 Ltd | Administrative & support | 2022 |
| E-Type Fabs NO 13 Ltd | Administrative & support | 2022 |
| E-Type Fabs NO 14 Ltd | Administrative & support | 2022 |
| E-Type Fabs NO 15 Ltd | Administrative & support | 2022 |
| E-Type Fabs NO 16 Ltd | Administrative & support | 2022 |
| E-Type Fabs NO 2 Ltd | Administrative & support | 2022 |
| E-Type Fabs NO 3 Ltd | Administrative & support | 2022 |
| E-Type Fabs NO 4 Ltd | Administrative & support | 2022 |
| E-Type Fabs NO 5 Ltd | Administrative & support | 2022 |
| E-Type Fabs NO 6 Ltd | Administrative & support | 2022 |
| E-Type Fabs NO 7 Ltd | Administrative & support | 2022 |
| E-Type Fabs NO 8 Ltd | Administrative & support | 2022 |
| E-Type Fabs NO 9 Ltd | Administrative & support | 2022 |
| E-Xtreme Moto Ltd | Wholesale & retail | 2021 |
| E. FIX 24/7 Ltd | Construction | 2014 |
| E.A Render Systems Ltd | Construction | 2020 |
| E.L.S Contracting Ltd | Construction | 2024 |
| E.P.E Solutions Ltd | Manufacturing | 2016 |
| Eacuk Ltd | Construction | 2026 |
| Eagle Communications Limited | Professional & scientific | 2010 |
| Eagley Holdings Limited | Professional & scientific | 2021 |
| Eaprinting Limited | Manufacturing | 2018 |
| Easby Flooring Limited | Construction | 1976 |
| Easby Ltd | Professional & scientific | 2021 |
| Easipay Carpets Limited | Construction | 2017 |
| Easipay Flooring Limited | Administrative & support | 2017 |
| Easipay Home Appliances Limited | Extraterritorial | 2017 |
| Easipay Home Interiors Limited | Extraterritorial | 2017 |
| Easipay Payments Ltd | Financial services | 2018 |
| Easipay Rugs Limited | Administrative & support | 2017 |
| Easipayments Ltd | Professional & scientific | 2009 |
| East Meets West Taekwondo Academy Ltd. | Education | 2021 |
| East Street Property Management Ltd | Households | 2017 |
| East West Retail Ltd | Wholesale & retail | 2017 |
| Eastfield Retreat Limited | Hospitality | 2023 |
| Easton Planning Services Limited | Administrative & support | 2007 |
| Eastyem Ltd | Wholesale & retail | 2025 |
| Easy Storage Ltd | Other services | 2019 |
| Easybox Storage Ltd | Administrative & support | 2024 |
| Easydrive Cars Ltd | Wholesale & retail | 2013 |
| Easyprep Ltd | Hospitality | 2020 |
| EAT Fresh Investments Limited | Hospitality | 2009 |
| EBM Managed Services Ltd | Administrative & support | 2005 |
| EC Surveying Limited | Professional & scientific | 2018 |
| Echarm Properties Limited | Real estate | 2019 |
| Echo 3 Coffee Ltd | Manufacturing | 2018 |
| Eclipse Distribution Limited | Wholesale & retail | 2024 |
| Eco Byte Ventures Limited | Hospitality | 2025 |
| Eco Hair Salon Limited | Other services | 2023 |
| Eco House Darlington Ltd | Real estate | 2021 |
| Eco Power Energy Limited | Construction | 2013 |
| Eco Power Hydrogen Limited | Construction | 2024 |
| Eco Power Infrastructure Limited | Construction | 2024 |
| Eco Power Solar Limited | Construction | 2024 |
| Eco Rend North East Limited | Construction | 2012 |
| Ecommerce Evolution Ltd | Wholesale & retail | 2015 |
| Ecommercesource Limited | Wholesale & retail | 2024 |
| Ecopower EV Limited | Construction | 2024 |
| Ecorson UK Ltd | Construction | 2023 |
| Ecowin Sustainable Floors Ltd | Construction | 2026 |
| Eden Cottage Care Home Limited | Health & social care | 2012 |
| Eden Flight Training Limited | Education | 2015 |
| Eden Garage Ltd | Wholesale & retail | 2015 |
| Eden Homes (Wales) Limited | Real estate | 2006 |
| Eden Properties(Darlington) Limited | Real estate | 2023 |
| Eden Skye Aesthetics Ltd | Other services | 2016 |
| Edessa Property Management LLP | | 2023 |
| Edgar F Shepherd Ltd | Manufacturing | 2010 |
| Edgar F. Shepherd (Holdings) Limited | Financial services | 2024 |
| Edgerley Electrical Services Ltd | Construction | 2019 |
| Edit Learning Limited | Extraterritorial | 2013 |
| Edward Robertson Limited | Information & communication | 2000 |
| Eelizabe Limited | Wholesale & retail | 2025 |
| Efinds Ltd | Wholesale & retail | 2023 |
| EG Motors Ltd | Wholesale & retail | 2022 |
| Eggyflomps Ltd | Wholesale & retail | 2025 |
| EI Creighton Logistics Ltd | Transport & logistics | 2025 |
| Eighth Wonder Properties Limited | Professional & scientific | 2025 |
| Eighties Doubt Productions Ltd | Administrative & support | 2023 |
| EJS Leasing Ltd | Wholesale & retail | 2020 |
| EKB Solutions Ltd | Information & communication | 2025 |
| EL Nino Limited | Other services | 2011 |
| Elan (North East) Ltd | Wholesale & retail | 2013 |
| Elbeshbishy General Trading Ltd | Wholesale & retail | 2025 |
| Elders Walker Glass Limited | Construction | 2005 |
| Eldric Ltd | Wholesale & retail | 2026 |
| Electronic Security Solutions Limited | Construction | 2000 |
| Electrosecure Ltd | Construction | 2023 |
| Elegance Lettings Ltd | Real estate | 2026 |
| Elestore Ltd | Wholesale & retail | 2018 |
| Eletriity Limited | Agriculture & fishing | 2006 |
| ELEV8 Flooring & Interiors Ltd | Construction | 2025 |
| Elevate Performance Healthcare Ltd | Health & social care | 2025 |
| Elevategoods Ltd | Wholesale & retail | 2024 |
| ELG Ecology Ltd | Professional & scientific | 2024 |
| Elgobba Trading Ltd | Wholesale & retail | 2025 |
| Elianna Properties Ltd | Households | 2018 |