| Priority Transport Ltd. | Transport & logistics | 2003 |
| Proeco Property Services Ltd | Construction | 2024 |
| Project Scaffolding SW Ltd | Construction | 2019 |
| Property Service Heroes Ltd | Extraterritorial | 2023 |
| Pure Shine Limited | Administrative & support | 2023 |
| Pyromatic Fire Suppression Ltd | Public administration | 2025 |
| Q14 Ltd | Information & communication | 2016 |
| Q595 Ltd | Other services | 2015 |
| QM Portfolios Limited | Real estate | 2021 |
| Quirky Retro Cards Limited | Wholesale & retail | 2020 |
| R & a Persey Limited | Manufacturing | 2012 |
| R & R Services (Devon) Ltd | Administrative & support | 2003 |
| R S Carpenters Ltd | Construction | 2013 |
| R W Hammett Electrical Limited | Construction | 2014 |
| R White & SON Limited | Construction | 2024 |
| R&R Civils Ltd | Construction | 2021 |
| R. & F.A. Batten Limited | Agriculture & fishing | 2006 |
| Rademeyers Ltd | Health & social care | 2025 |
| Radscan Digital Ltd | Professional & scientific | 2024 |
| Raidel UK Ltd | Transport & logistics | 2019 |
| Rainwood Limited | Agriculture & fishing | 2017 |
| Rainy SUE Ltd | Manufacturing | 2022 |
| Rani Retails Ltd | Wholesale & retail | 2022 |
| RAW Electrical Limited | Construction | 2005 |
| Rayda Plastics Limited | Manufacturing | 1976 |
| Real Pro Gear Limited | Manufacturing | 2011 |
| Red Doors Farm Holiday Cottages Limited | Hospitality | 2011 |
| Red Jackal Games Limited | Information & communication | 2026 |
| Refcool Refrigeration Limited | Other services | 1996 |
| REJOICEIN4K Ltd | Information & communication | 2025 |
| Reliefchefs Ltd | Administrative & support | 2023 |
| Relv Limited | Manufacturing | 2023 |
| Rent Smart Property Ltd | Real estate | 2024 |
| Renttech Ltd | Administrative & support | 2025 |
| Replapse Ltd | Information & communication | 2026 |
| Respectech Limited | Manufacturing | 2021 |
| Rfid Cloaked Ltd | Manufacturing | 2015 |
| RG Roofing and Building Services Limited | Construction | 2023 |
| Richard Batten Limited | Administrative & support | 2006 |
| Richard Carman Limited | Professional & scientific | 2003 |
| River Accounting Limited | Professional & scientific | 2020 |
| RJ Transport Solutions Ltd | Transport & logistics | 2026 |
| RJC Electrical Ltd | Construction | 2018 |
| RMP Farm Ltd | Agriculture & fishing | 2005 |
| Robert Norrish Carpets & Flooring Ltd | Administrative & support | 2010 |
| Rope Access Tree Services Ltd | Agriculture & fishing | 2021 |
| Rowe & Co Limited | Administrative & support | 2012 |
| Rowe Atlantic Limited | Administrative & support | 2012 |
| Roxy’S Locks Mobile Hair Extensions Ltd | Other services | 2025 |
| Roymo Medical Ltd | Health & social care | 2026 |
| RPH Civil Solutions Ltd | Professional & scientific | 2024 |
| RTP Materials Handling Limited | Wholesale & retail | 2008 |
| Rudge Enthusiasts Club Limited | Other services | 1997 |
| Rudge-Whitworth (Coventry), Limited | Extraterritorial | 1999 |
| Rudge-Whitworth Motorcycles, Limited | Extraterritorial | 1999 |
| Rudge-Whitworth, Limited | Extraterritorial | 2005 |
| Rumwell Financial Services Ltd | Financial services | 2012 |
| Rvelr Ltd | Administrative & support | 2025 |
| Rzevski Research Ltd | Information & communication | 2020 |
| S and G Logistics Ltd | Transport & logistics | 2024 |
| S and G Maintenance Ltd | Wholesale & retail | 2023 |
| S T Electrical SW Limited | Manufacturing | 2019 |
| S&J Hosting Ltd | Hospitality | 2026 |
| S. M. Kittow Plumbing & Heating Ltd | Construction | 2014 |
| Sailing Occasions Ltd | Real estate | 2020 |
| SAM Felton Ltd | Wholesale & retail | 2018 |
| Samiisra Ltd | Hospitality | 2015 |
| Sarum Investments Limited | Real estate | 1999 |
| Saunair Ltd | Other services | 2021 |
| Sawadee Thai Food Restaurant Ltd | Hospitality | 2025 |
| SAX Purdie Ltd | Construction | 2020 |
| Seastructures Ltd | Professional & scientific | 2022 |
| Secure Scaffolding (Devon) Ltd | Construction | 2025 |
| Sedgwick Lettings Ltd | Real estate | 2024 |
| Sedis 9 Studios Ltd | Information & communication | 2019 |
| Seed to Skin Elixir Ltd | Manufacturing | 2025 |
| Sefconsult Ltd | Professional & scientific | 2019 |
| Selgars Mill Estate Limited | Real estate | 2024 |
| SG (Uffculme) Limited | Wholesale & retail | 2009 |
| Shalom (Devon) Ltd | Health & social care | 2015 |
| Shaw Properties Investment Ltd | Real estate | 2026 |
| Shear Soccer Ltd | Other services | 2022 |
| Shepherds Cottages Limited | Households | 2019 |
| Shepherds Court (Cullompton) Management Company Ltd | Administrative & support | 2015 |
| Shere Engineering Ltd | Wholesale & retail | 2012 |
| Shine Recruitment Southwest Limited | Administrative & support | 2010 |
| SID Vale Holdings Ltd | Real estate | 2021 |
| Silver Spring Consultants Limited | Administrative & support | 2019 |
| Simple Beauty Cullompton Ltd | Other services | 2024 |
| Siva Retail Ltd | Wholesale & retail | 2013 |
| SJB Accountancy & Payroll Services Limited | Professional & scientific | 2025 |
| SJP Automotive Limited | Manufacturing | 2013 |
| Sky Platform Hire Limited | Administrative & support | 1981 |
| Sky Property Asset's Ltd | Real estate | 2021 |
| Sliced Pictures Ltd | Information & communication | 2008 |
| Smart Grooming Limited | Wholesale & retail | 2011 |
| Smiffy's Auto Upholstery Ltd | Manufacturing | 2018 |
| Smile Beautiful Group Limited | Financial services | 2026 |
| Snotra Ltd | Information & communication | 2025 |
| Solace Tax and Legal Solutions Ltd | Professional & scientific | 2021 |