| Entro Ltd | Wholesale & retail | 2016 |
| ENU Ethio Restaurant Limited | Hospitality | 2025 |
| Enuyami Properties Limited | Real estate | 2026 |
| Enviro OIL Environmental Solutions Experts Ltd | Water & waste | 2026 |
| Enviro Rail Engineering Ltd | Construction | 2025 |
| Environment Cleaning Services Ltd. | Administrative & support | 2015 |
| Envision Contracting Ltd | Administrative & support | 2016 |
| Envision Ventures Ltd | Wholesale & retail | 2025 |
| EOB Advisory Limited | Professional & scientific | 2026 |
| Epath Limited | Extraterritorial | 2015 |
| Epathusa Limited | Extraterritorial | 2012 |
| EPC London Ltd | Professional & scientific | 2023 |
| Eperficient Limited | Administrative & support | 2024 |
| Epharm Healthcare Ltd | Health & social care | 2014 |
| Ephraim & Co Services Ltd | Health & social care | 2023 |
| Epic Cleaning and Commercial Buildings Solutions Ltd | Administrative & support | 2025 |
| Epic Cleaning Services Ltd | Administrative & support | 2022 |
| Epic Horizon Ltd | Information & communication | 2024 |
| Epryme Ltd | Financial services | 2014 |
| Epsom Therapies Limited | Health & social care | 2021 |
| Equal Frame Productions Limited | Information & communication | 2025 |
| Equality Property Ltd | Health & social care | 2025 |
| Equator Line Ltd | Transport & logistics | 2021 |
| Equitable Investments Limited | Real estate | 2016 |
| Equity Properties Limited | Real estate | 2015 |
| ER Estates Limited | Wholesale & retail | 2009 |
| ER Logistics UK Limited | Transport & logistics | 2003 |
| ER Transformations Ltd | Information & communication | 2023 |
| Eram Property Ltd | Real estate | 2023 |
| Erebos Limited | Wholesale & retail | 2020 |
| ERI Transport Limited | Transport & logistics | 2024 |
| Eriador Consulting Limited | Information & communication | 2025 |
| Eric K Properties Limited | Real estate | 2024 |
| Eric Patrick Care Ltd | Real estate | 2012 |
| Eric Patrick Estates Ltd | Real estate | 2019 |
| Eric's Construction Solutions Ltd | Construction | 2014 |
| Eries Estates Limited | Real estate | 2017 |
| Eries Solutions Ltd | Professional & scientific | 2005 |
| Erith Convenience Store Ltd | Wholesale & retail | 2019 |
| Ermine Court (Huntingdon) Management Company Limited | Households | 1981 |
| Ermyn Way (Leatherhead) Residents Association Limited | Households | 2011 |
| Ernest AMA Company Limited | Information & communication | 2018 |
| Ernest AMA Technology Ltd | Information & communication | 2026 |
| Eros Solutions Limited | Professional & scientific | 2016 |
| ERP Euro Consult Limited | Information & communication | 2013 |
| Ervin Promotions Limited | Professional & scientific | 2010 |
| ES Coffee Ltd | Hospitality | 2019 |
| ES Gardening Limited | Administrative & support | 2021 |
| ES Properties Limited | Extraterritorial | 2014 |
| Esai Limited | Real estate | 2013 |
| Esbonn Limited | Health & social care | 2023 |
| Esbp Limited | Administrative & support | 2013 |
| Esemar Limited | Financial services | 2025 |
| Esence Limited | Manufacturing | 2022 |
| Eserve Infotech UK PVT Ltd | Information & communication | 2025 |
| ESG Holdco Ltd | Information & communication | 2025 |
| Esher Place Residents Limited | Households | 1975 |
| Esher Support C.I.C. | Health & social care | 2025 |
| Eskar Ltd | Hospitality | 2022 |
| Eskays Cheltenham Limited | Real estate | 2025 |
| Eskimo Limited | Real estate | 1997 |
| Esky Express Limited | Transport & logistics | 2026 |
| Esky Productions Limited | Information & communication | 2023 |
| Esky Supermarket Ltd | Wholesale & retail | 2025 |
| Esmonde Drive Residents Company Limited | Households | 1998 |
| Esports Worldwide Ltd | Information & communication | 2019 |
| Espresso Digital Ltd | Information & communication | 2022 |
| Esprit Residents Company Limited | Households | 2007 |
| Esra - ZA Catering Limited | Hospitality | 2015 |
| Essd Construction Limited | Construction | 2026 |
| Essence Medics Ltd | Health & social care | 2022 |
| Essential Care Ltd | Health & social care | 2020 |
| Essential Goods Ltd | Wholesale & retail | 2020 |
| Essential Living Care Ltd | Health & social care | 2021 |
| Essential Services (UK) Limited | Administrative & support | 2006 |
| Essential Workers Ltd | Other services | 2019 |
| Essentially Wine Limited | Wholesale & retail | 2004 |
| Essentials (Acton) Limited | Wholesale & retail | 2010 |
| Essex Brewery Management Company Limited | Households | 2018 |
| Essex Cigar Company Limited | Wholesale & retail | 2025 |
| Essex Pharma Limited | Wholesale & retail | 2015 |
| Essien Properties Ltd | Administrative & support | 2010 |
| Estate Links International Limited | Real estate | 2023 |
| Este Kent Ltd | Administrative & support | 2020 |
| Esteemed Recruitment Group Ltd | Professional & scientific | 2020 |
| Estetika Ltd | Construction | 2017 |
| Esther Community Enterprise | Water & waste | 2008 |
| Esther's Haven Ltd | Health & social care | 2026 |
| Estherfakprospect Base Ltd | Construction | 2023 |
| Estherfred Healthcare Services Limited | Health & social care | 2013 |
| Esthers Properties Ltd | Real estate | 2024 |
| Estheticslounge Ltd | Other services | 2023 |
| Estia Investments Ltd | Real estate | 2020 |
| Estisa Care Ltd | Health & social care | 2020 |
| Estmanco (Blowden) Limited | Households | 1979 |
| Estmanco (Brabazon Street) Limited | Households | 1979 |
| Estmanco (Ollgar Close) Limited | Households | 1979 |
| Estore Limited | Wholesale & retail | 2024 |
| Estro Ltd | Hospitality | 2017 |
| Etech Emporium Ltd | Wholesale & retail | 2025 |