| Ember Virtual Assistant Ltd | Administrative & support | 2023 |
| Emblem Group Ltd | Construction | 2014 |
| EMC Productions Media Ltd | Information & communication | 2025 |
| Emekasportfolio Limited | Information & communication | 2025 |
| Emerald ASC Ltd | Education | 2015 |
| Emerald Electrics Limited | Construction | 2020 |
| Emerald Green Care Ltd | Health & social care | 2017 |
| Emerald Green Cleaners Limited | Administrative & support | 2024 |
| Emerald Hospitality Group Ltd | Hospitality | 2018 |
| Emerald House RTM Company Limited | Households | 2019 |
| Emerald Leaves Ltd | Construction | 2015 |
| Emergent Performance Ltd | Arts & recreation | 2021 |
| Emerson 68 Limited | Construction | 2020 |
| Emeson Ltd | Construction | 2017 |
| EMG Cleaning Limited | Administrative & support | 2001 |
| EMG Cybersec Ltd | Administrative & support | 2019 |
| EMI Media Ltd | Professional & scientific | 2018 |
| Emi&Bo Ltd | Construction | 2025 |
| Emid Core Ltd | Professional & scientific | 2025 |
| Eminent Support Services Ltd | Health & social care | 2015 |
| Emkay Healthcare Ltd | Health & social care | 2019 |
| Emlagh Court RTM Company Limited | Households | 2026 |
| Emma Johnson Therapies Ltd | Administrative & support | 2021 |
| Emma Norris Consulting Ltd | Professional & scientific | 2022 |
| Emmacare Services Ltd | Health & social care | 2015 |
| Emmamic Ltd | Real estate | 2017 |
| Emmanuel Black Limited | Wholesale & retail | 2025 |
| Emmanuel Corporate Limited | Manufacturing | 2009 |
| Emmanuel Development Consultancy Ltd | Health & social care | 2026 |
| Emmanuel Tutu's Company Ltd | Transport & logistics | 2019 |
| Emmer Green Flat Management Company Limited | Households | 2003 |
| Emmy the Writer Ltd | Arts & recreation | 2024 |
| EMP Enterprises Limited | Wholesale & retail | 2011 |
| Empat Ventures Ltd | Real estate | 2021 |
| Empire Apartments (Freehold) Limited | Households | 2004 |
| Empire F&B Ltd | Manufacturing | 2022 |
| Empire Gate Holdings Ltd | Financial services | 2025 |
| Empire Grounds Maintenance Ltd | Administrative & support | 2025 |
| Empire Real Estate Ltd | Real estate | 2022 |
| Empirebus Limited | Transport & logistics | 2007 |
| Employment Advocacy Services Limited | Administrative & support | 2008 |
| Emporg Ltd | Wholesale & retail | 2022 |
| Emporium Corner Ltd | Wholesale & retail | 2025 |
| Empourim Phones Ltd | Wholesale & retail | 2024 |
| Empower Moves CIC | Education | 2025 |
| Empower Psychiatry Services Limited | Health & social care | 2026 |
| Empower Young Lives Limited | Hospitality | 2026 |
| Empress Court (Morecambe) Limited | Households | 2000 |
| Empsi Taekwondo Ltd | Arts & recreation | 2013 |
| Empwr Limited | Education | 2024 |
| Empyrea Group Ltd | Extraterritorial | 2026 |
| Empyrea Holdings Ltd | Financial services | 2026 |
| Emvels Logistics Ltd | Professional & scientific | 2021 |
| Emward Consulting Ltd | Professional & scientific | 2019 |
| Emzrel Corporation Limited | Professional & scientific | 2023 |
| EN Optima Figura Limited | Wholesale & retail | 2024 |
| EN Route Investments Ltd | Real estate | 2019 |
| EN Route Solutions Limited | Information & communication | 2000 |
| ENA Partnership Limited | Extraterritorial | 2012 |
| Enabled Care Agency Limited | Administrative & support | 2025 |
| Enabled Health Ltd | Health & social care | 2014 |
| Enablement Healthcare Limited | Health & social care | 2020 |
| Enablr Ltd | Professional & scientific | 2020 |
| Enaf Property Ltd | Real estate | 2019 |
| Enborne Park Freehold (Newbury) Limited | Extraterritorial | 2013 |
| Enchill Investments Ltd | Real estate | 2021 |
| Encompass Latc Ltd | Hospitality | 2016 |
| Enders Investment Company Limited | Financial services | 1988 |
| Endian Building Ltd | Construction | 2021 |
| Endorphin Studio Ltd | Professional & scientific | 2021 |
| Endotherm Games Ltd | Information & communication | 2025 |
| Energem Services Limited | Professional & scientific | 2007 |
| Energy and Light Ltd | Manufacturing | 2018 |
| Energy Assessors (Surrey) Ltd | Construction | 2008 |
| Energy Asset Management Ltd | Professional & scientific | 2014 |
| Energy Home Limited | Other services | 2019 |
| Energy Star Home Improvements Ltd | Construction | 2019 |
| Engelberg Group Co., Ltd | Wholesale & retail | 2023 |
| Engentic Limited | Information & communication | 2025 |
| Engine of Levitation Limited | Professional & scientific | 2016 |
| Englishcombe Court Management Company Limited | Households | 2002 |
| Englon Limited | Real estate | 2022 |
| ENI Fintech Ltd | Professional & scientific | 2022 |
| Enic Medicals Ltd | Health & social care | 2013 |
| Enigma Venture Holdings Limited | Information & communication | 2026 |
| Enjoy International Limited | Wholesale & retail | 2007 |
| Enjoy Tomorrow Limited | Arts & recreation | 2025 |
| Enki Designs Ltd | Construction | 2018 |
| Enlighten One Limited | Other services | 2015 |
| Enluka Consultancy Services Limited | Information & communication | 2023 |
| Enniecoco Ltd | Other services | 2026 |
| ENO Bemah Ltd | Other services | 2014 |
| Enod Productions Limited | Professional & scientific | 2014 |
| Enotech Ltd | Hospitality | 2021 |
| Enriching Lifes Ltd | Wholesale & retail | 2023 |
| Enright Property Ltd | Real estate | 2021 |
| Ensemble Consulting Ltd | Information & communication | 2012 |
| Enteck Electrical Services Ltd | Construction | 2024 |
| Entice Travel Ltd | Administrative & support | 2014 |
| Entrepreneurial Brands INT Ltd | Wholesale & retail | 2021 |