| Prestige Homes of Sussex Limited | Real estate | 2016 |
| Prestigious Stone Installation Ltd | Construction | 2024 |
| Prestigious Stone Masonry Ltd | Manufacturing | 2020 |
| Pretty Permanent Make-Up Limited | Other services | 2012 |
| Primary Contracts Limited | Households | 2019 |
| Prime Fit Ltd | Construction | 2024 |
| Prime JGS Consulting Ltd | Professional & scientific | 2024 |
| Prismatic Design Solutions Limited | Administrative & support | 2009 |
| Pritchards Removals Limited | Transport & logistics | 2019 |
| Probity Commercial Finance Ltd | Professional & scientific | 2025 |
| Process Water Services Ltd | Manufacturing | 2002 |
| Procura Partners Ltd | Professional & scientific | 2026 |
| Producer Roaster Forum Ltd | Professional & scientific | 2019 |
| Professional Applications Limited | Professional & scientific | 2004 |
| Project X Strategies Limited | Information & communication | 2020 |
| Property and Homesurveys Limited | Professional & scientific | 2022 |
| Prosperity IFA Limited | Financial services | 2011 |
| Pure Hair Design Limited | Other services | 2002 |
| Pure Media Print Solutions Ltd | Manufacturing | 2020 |
| Pusanon Thai Restaurant Ltd | Hospitality | 2015 |
| PW Property Management Ltd | Real estate | 2020 |
| Qmead Portfolio Limited | Real estate | 2020 |
| QRT Power Ltd | Administrative & support | 2024 |
| Qualitent Limited | Information & communication | 2022 |
| Quality Vehicle Contracts Limited | Financial services | 1997 |
| Quantum Print Solutions Limited | Manufacturing | 2014 |
| Quedos Building Consultants Limited | Administrative & support | 2012 |
| Queensbridge Industrial Park Management Limited | Real estate | 1999 |
| Qwood Property UK Ltd | Construction | 2024 |
| R J Burrow Limited | Wholesale & retail | 2003 |
| R Priyanka Ltd | Wholesale & retail | 2024 |
| R&M Willink and Sons Limited | Construction | 2007 |
| R. J. Rudd & Co. Limited | Manufacturing | 2016 |
| R. J. Rudd Co Limited | Manufacturing | 2022 |
| R.J. Cridge Limited | Construction | 1976 |
| Range 2000 Limited | Transport & logistics | 2002 |
| Rawlings Communications Limited | Administrative & support | 2013 |
| RAY Taylor GAS Engineer Limited | Construction | 2005 |
| Real Value Limited | Financial services | 2020 |
| Realms Group Ltd | Arts & recreation | 2025 |
| Red Cat Enterprises Ltd | Information & communication | 2025 |
| Redewater Holdings Limited | Financial services | 2024 |
| Redguard Group Limited | Extraterritorial | 2020 |
| Redshield Accountancy Services Ltd | Information & communication | 1994 |
| Redshield Business Solutions Limited | Professional & scientific | 2009 |
| Redshield Probate Services Limited | Professional & scientific | 2015 |
| Redshield Professional Services Limited | Extraterritorial | 2015 |
| Redwing Property Services Ltd | Construction | 2014 |
| Redwing Roofing Ltd | Construction | 2013 |
| Redwood Assured Limited | Transport & logistics | 2017 |
| Reef Guru Ltd | Professional & scientific | 2016 |
| Reef-Edge Ltd | Information & communication | 2000 |
| Reeweb Ltd | Wholesale & retail | 2014 |
| Reflowai Limited | Information & communication | 2025 |
| Regals DEV Co Ltd | Professional & scientific | 2026 |
| Relay Construction Limited | Construction | 2000 |
| Relo Lite Ltd | Administrative & support | 2020 |
| Remas & Sons Limited | Wholesale & retail | 2003 |
| Remas Investments Limited | Real estate | 2012 |
| Rend-Facades Limited | Construction | 2019 |
| Reninvest Sustainability Limited | Professional & scientific | 2018 |
| Renovation and Design Solutions Ltd | Real estate | 2024 |
| Rep-It Limited | Manufacturing | 2017 |
| Replenify Ltd | Wholesale & retail | 2023 |
| Research Consulting Trading Limited | Health & social care | 2025 |
| Rhiannon D'Averc Writer Ltd | Information & communication | 2023 |
| Rhys C Newman IT Limited | Information & communication | 2025 |
| Rhysprop Ltd | Real estate | 2026 |
| Richard Brinklow Aviation Limited | Other services | 1995 |
| Richard West Services Limited | Other services | 2018 |
| Richards Fencing Ltd | Construction | 2017 |
| RIG Tours Ltd | Professional & scientific | 2021 |
| Rigden-Gray Chimney Services Ltd | Construction | 2023 |
| Right at the Top Ltd | Professional & scientific | 2021 |
| Rileyprop Ltd | Real estate | 2026 |
| Ritzy Bits Clothing Limited | Wholesale & retail | 2023 |
| Rivard Ltd | Professional & scientific | 2025 |
| Rivoira UK Limited | Wholesale & retail | 2024 |
| RJG IT Consulting Limited | Information & communication | 2021 |
| RJH Consulting (East Sussex) Limited | Construction | 2018 |
| RJY Trading Ltd | Wholesale & retail | 2023 |
| RM7 Management Ltd | Real estate | 2024 |
| RMA Watts Construction Ltd | Construction | 2010 |
| RMR Finance Ltd | Financial services | 2021 |
| Robert W Belcher Limited | Professional & scientific | 2001 |
| Robertsione Productions Limited | Information & communication | 2010 |
| Robprop Ltd | Construction | 2026 |
| Rockstead Groundworks & Contruction Ltd | Construction | 2025 |
| Roebling Projects Ltd | Real estate | 2022 |
| Roofing Sussex Ltd | Construction | 2024 |
| Rookery Caravan Site Limited | Real estate | 1961 |
| Room 4 Group Ltd | Information & communication | 2006 |
| Rose Court Management Crowborough Limited | Hospitality | 1994 |
| Rotherfield & Mark Cross Bonfire Society Ltd | Arts & recreation | 2006 |
| Rotherfield Village Pre-School | Education | 2011 |
| Roundtable PT Limited | Administrative & support | 2010 |
| Rowans Wood Limited | Real estate | 2012 |
| Rowbur Products Limited | Manufacturing | 2020 |
| Rowbur Services Limited | Administrative & support | 2020 |
| Rowe Advisory Limited | Professional & scientific | 2026 |