| Roundway Court RTM Company Limited | Households | 2005 |
| Rouqa Ltd | Wholesale & retail | 2022 |
| Rousselsolutions Limited | Information & communication | 2025 |
| Route Direct Ltd | Transport & logistics | 2025 |
| ROUTE1FITNESS Ltd | Arts & recreation | 2022 |
| Routine Office Cleaning Ltd | Administrative & support | 2019 |
| Rowfant Caldyne Limited | Administrative & support | 2021 |
| Rowfant Ltd | Information & communication | 2020 |
| Rowfant Mill Pond Fishing Syndicate Limited | Agriculture & fishing | 2025 |
| Rowfant Trading Ltd | Hospitality | 2013 |
| Roxbill Properties Ltd. | Real estate | 2007 |
| ROY Thomas Williams Ltd | Extraterritorial | 2023 |
| Royal Creative Ltd | Professional & scientific | 2024 |
| Royale Glam Ltd | Other services | 2026 |
| Royce Cleaning Services Ltd | Administrative & support | 2026 |
| RP Carpet Solutions Ltd | Administrative & support | 2026 |
| Rpc-It Limited | Information & communication | 2021 |
| RPL Power Ltd | Construction | 2011 |
| RPM Investments Limited | Professional & scientific | 1976 |
| Rpmsussex Ltd | Wholesale & retail | 2024 |
| Rrawlings Limited | Households | 2016 |
| RRE Developments Ltd | Construction | 2018 |
| RRR Property Maintenance Ltd | Administrative & support | 2021 |
| RS GAS Ltd | Construction | 2026 |
| RS Private Hire Services Ltd | Transport & logistics | 2018 |
| RSK97 Ltd | Professional & scientific | 2023 |
| RSN Design & Build Ltd | Construction | 2019 |
| RSW Grow Limited | Wholesale & retail | 2026 |
| Ruach House Ltd | Wholesale & retail | 2023 |
| Rubyrou Ltd | Households | 2022 |
| Rucgistics Company Ltd | Professional & scientific | 2018 |
| Rudaw - Speed Ltd | Administrative & support | 2022 |
| Rufwood Residents Association Ltd | Real estate | 2025 |
| RUG ‘N’ Roll Ltd | Manufacturing | 2025 |
| Rugby 248 Ltd | Real estate | 2025 |
| Rugpol Ltd | Wholesale & retail | 2016 |
| Rulos Limited | Health & social care | 2012 |
| Rurdrips Ltd | Wholesale & retail | 2026 |
| Rusadi Ltd | Health & social care | 2017 |
| Russell Executive Ltd | Transport & logistics | 2018 |
| Russell Place (Crawley Down) Management Co Ltd | Households | 2022 |
| Rustic Bars Ltd | Hospitality | 2025 |
| Rustic Mobile Bars Ltd | Hospitality | 2019 |
| Rustic Riley Ltd | Manufacturing | 2025 |
| Ruth Cleaning Service Ltd | Administrative & support | 2021 |
| Ruyi Food Ltd | Hospitality | 2024 |
| RV Heating & Electrical Limited | Construction | 2023 |
| Rvrawlings LLP | | 2017 |
| RWB Network Solutions Ltd | Extraterritorial | 2023 |
| Rxpharmaco Ltd | Health & social care | 2013 |
| Ryan Joshua David Williams Ltd | Extraterritorial | 2024 |
| Ryan Road Planing Ltd | Transport & logistics | 2026 |
| Rydex Cars Ltd | Transport & logistics | 2025 |
| Rylee Demolition and Groundwork Ltd | Construction | 2014 |
| Rynd Group Limited | Real estate | 2025 |
| Rājati Home Ltd | Wholesale & retail | 2022 |
| S & a Platinum Catering Ltd | Hospitality | 2026 |
| S & N Tyres Ltd | Wholesale & retail | 2020 |
| S & W Property Solutions Ltd | Real estate | 2016 |
| S a Sportsworld Limited | Wholesale & retail | 2008 |
| S and P Automotive Holdings Limited | Financial services | 2015 |
| S Bansal Ltd | Professional & scientific | 2023 |
| S Beare Properties Limited | Real estate | 2022 |
| S C Parts Group Limited | Wholesale & retail | 1984 |
| S D a Services (Sussex) Limited | Other services | 2003 |
| S G Build Ltd | Construction | 2016 |
| S J Inventory Services Ltd | Professional & scientific | 2019 |
| S J Supermarket Ltd | Wholesale & retail | 2018 |
| S L Restoration Limited | Wholesale & retail | 2000 |
| S M Pharm Ltd | Administrative & support | 2018 |
| S Mazzei Interior Design Ltd | Professional & scientific | 2021 |
| S O S Systems Limited | Wholesale & retail | 1985 |
| S R Enterprise UK Limited | Professional & scientific | 2009 |
| S Sesanga Limited | Health & social care | 2015 |
| S&K Service Ltd | Transport & logistics | 2013 |
| S&M Antique & Vintage Furniture Ltd | Wholesale & retail | 2022 |
| S&N Property Rentals Limited | Real estate | 2013 |
| S&O Brickwork Limited | Construction | 2018 |
| S&P Detailing Ltd | Wholesale & retail | 2024 |
| S&R Consultancy Group Ltd | Real estate | 2022 |
| S&S Barrington Ltd | Professional & scientific | 2018 |
| S&S Barrington Properties Ltd | Real estate | 2020 |
| S&S First Steps Ltd | Real estate | 2024 |
| S&S Fresh Start Cleaning Limited | Administrative & support | 2026 |
| S. Courtman Ltd | Information & communication | 2024 |
| S. Griffin Residential Ltd | Real estate | 2026 |
| S. Tombolis & Sons (London) Limited | Construction | 1972 |
| S.H. Renovations Ltd | Construction | 2021 |
| S.K. Fascias Limited | Construction | 2003 |
| S.Sogari Promotions & Beauty Limited | Other services | 2013 |
| S.W. Tooling Limited | Professional & scientific | 1998 |
| S2L Procurement Consulting Ltd | Professional & scientific | 2025 |
| S2P (Sussex) Consultancy Limited | Information & communication | 2026 |
| SA Installations (UK) Ltd | Construction | 2014 |
| Saad Newsagent Ltd | Wholesale & retail | 2013 |
| Saaman Limited | Administrative & support | 2003 |
| Saar Dental Ltd | Health & social care | 2017 |
| SAB Facilities Services Limited | Administrative & support | 2026 |
| Saba Caring Services Limited | Health & social care | 2013 |
| Sabacare Ltd | Health & social care | 2019 |