| Empire Autos N.I. Ltd | Wholesale & retail | 2021 |
| Empire Poppy Store CIC | Wholesale & retail | 2022 |
| Empire Sales & Distribution Limited | Wholesale & retail | 2017 |
| Empower Flower Workshops Ltd | Education | 2026 |
| EMS Environmental Marketing Solutions Ltd | Manufacturing | 2006 |
| Endeavour Building Limited | Financial services | 2017 |
| Endeavour NO. 1 Limited | Financial services | 2017 |
| Endeavour NO. 4 Limited | Financial services | 2018 |
| Endeavour NO.3 Limited | Financial services | 2018 |
| Endeavour NO.7 Limited | Financial services | 2026 |
| Energy Control Ireland Limited | Administrative & support | 2008 |
| Energy Wise Electrical Ltd | Extraterritorial | 2023 |
| Engineered Supplements Ltd | Manufacturing | 2022 |
| Enhance Aesthetics by Alana Ltd | Wholesale & retail | 2024 |
| Enhance Analytics Limited | Information & communication | 2024 |
| Enterprise Staffing Solutions Ltd | Administrative & support | 2024 |
| Enviro NI Pest Control Solutions Ltd | Administrative & support | 2016 |
| Environmental Consultancy Services (Ireland) Limited | Professional & scientific | 2019 |
| Environmental Packaging + Recycling Ltd | Water & waste | 2003 |
| Envision Intelligent Solutions Limited | Administrative & support | 2010 |
| Epic Design Group Ltd | Other services | 2018 |
| Epitome Living Ltd | Information & communication | 2017 |
| Epmac Services Ltd | Manufacturing | 2018 |
| Eprinting UK Limited | Information & communication | 2016 |
| Epworth Playgroup | Education | 2013 |
| EQI Craigavon Ltd | Manufacturing | 2013 |
| Equine-X Ltd | Manufacturing | 2021 |
| Eravia Ltd | Professional & scientific | 2025 |
| Erickson Properties Ltd | Construction | 2026 |
| Erinhill Limited | Financial services | 2009 |
| Erwin Peat Ltd | Mining & quarrying | 2011 |
| ES ATO Trading Limited | Wholesale & retail | 2025 |
| ESC Environmental Services Consultancy Ltd | Professional & scientific | 2016 |
| Escro Limited | Hospitality | 2012 |
| Eshwary Capital Limited | Construction | 2024 |
| Esky Phone Sales Ltd | Wholesale & retail | 2025 |
| Esky Repair Ltd | Other services | 2024 |
| Euroit Ltd | Information & communication | 2023 |
| Eurovape Ltd | Wholesale & retail | 2023 |
| EVA (1981) Ltd | Health & social care | 2020 |
| Evalution Consulting Limited | Information & communication | 2023 |
| EVC Coffee Limited | Hospitality | 2025 |
| Evenmore Holdings Ltd | Other services | 2026 |
| Event Nest Group Limited | Information & communication | 2026 |
| Evernue Media Ltd | Professional & scientific | 2020 |
| Eversend Ltd | Other services | 2025 |
| Evolution Motor Works Ltd | Wholesale & retail | 2014 |
| Evolve Electrical Engineering (NI) Limited | Construction | 2018 |
| EVY Nails Ltd | Other services | 2026 |
| Exoscar Limited | Other services | 2016 |
| Expert Pest Control Limited | Agriculture & fishing | 2014 |
| Express Distribution Services Ltd | Transport & logistics | 1997 |
| Exterior Excellence Cleaning Company Limited | Administrative & support | 2025 |
| EZ Software Solutions Limited | Information & communication | 2019 |
| Ezkeyz Limited | Wholesale & retail | 2026 |
| F K Contracts Ltd | Construction | 2023 |
| F M Mulholland Ltd | Professional & scientific | 2010 |
| F3 Engineering Limited | Manufacturing | 1980 |
| Fabric First Construction Ltd | Construction | 2017 |
| Fabritec Steel Limited | Construction | 2019 |
| Factory Outlet 123 Limited | Wholesale & retail | 2025 |
| Fade Location Turkish Barber Ltd | Other services | 2026 |
| Fairhouse Developments Ltd | Construction | 2013 |
| Falcon Electrical Contracts Ltd | Manufacturing | 2025 |
| Falcon Fuel (N.I.) Ltd | Professional & scientific | 2019 |
| Faluka Group UK Ltd | Financial services | 2026 |
| Farland Advisory Limited | Construction | 2015 |
| Farland Development Company Limited | Construction | 2013 |
| Farland Holdings Ltd | Financial services | 2018 |
| Farlough Manor Management Co Ltd | Households | 2016 |
| Farm Machinery Parts NI Limited | Manufacturing | 2025 |
| Farm With Kerr Limited | Agriculture & fishing | 2019 |
| Farmsafe Limited | Administrative & support | 2024 |
| Farringford Foods Co. Ltd. | Manufacturing | 1993 |
| FBT Mushrooms Limited | Agriculture & fishing | 2016 |
| FD Hospitality Ltd | Hospitality | 2021 |
| Fear Contracts Ltd | Manufacturing | 2019 |
| Fearon Property Group Limited | Real estate | 2026 |
| Feeney Flooring & Blinds Ltd | Wholesale & retail | 2025 |
| Fegan & SON Property Experts Ltd | Real estate | 2015 |
| Fegan Holdings Ltd | Financial services | 2026 |
| Fegan Properties Ltd | Real estate | 2015 |
| Ferntree Limited | Real estate | 2020 |
| Ferone Courier Limited | Transport & logistics | 2014 |
| Ferrard Grange Management Company Limited | Households | 2016 |
| Ffbelfast Ltd | Hospitality | 2025 |
| Fhdd Ltd | Wholesale & retail | 2024 |
| Field and Flesh Ltd | Wholesale & retail | 2025 |
| Fikka Coffee Ltd | Hospitality | 2024 |
| Fila Properties Ltd | Real estate | 2017 |
| Finbrook Investments Limited | Real estate | 1995 |
| Fine Foods & Baked Goods Ltd | Hospitality | 2021 |
| Fintry Properties Limited | Construction | 2006 |
| Firehow Limited | Administrative & support | 2017 |
| First Preference Medical Ltd | Health & social care | 2024 |
| First Reaction Ltd | Manufacturing | 2017 |
| Fitness Factory Lurgan Limited | Arts & recreation | 2021 |
| Fitzmaurice Mcconville & Co Limited | Professional & scientific | 2006 |
| Fivestar Associates Limited | Real estate | 2006 |
| FIX My Tech Ltd | Wholesale & retail | 2020 |