| ON the Rock Classic & Custom Limited | Wholesale & retail | 2026 |
| Onboard Events UK Ltd | Arts & recreation | 2026 |
| One Door Down Limited | Real estate | 2013 |
| One Door Down Manchester Ltd | Real estate | 2014 |
| One Door Down North West Ltd | Real estate | 2016 |
| One One SIX Cowes Limited | Hospitality | 2025 |
| Online Leisurewear Ltd | Wholesale & retail | 2025 |
| Opal Coachways LLP | | 2011 |
| Opal Holidays Limited | Extraterritorial | 2017 |
| Opal Travel Group Limited | Administrative & support | 2011 |
| Opal Travel Services Limited | Professional & scientific | 2011 |
| Opex Groundworks and Civil Engineering Ltd | Construction | 2020 |
| Orca Consulting Services Ltd | Professional & scientific | 2020 |
| Oriel Laboratories Limited | Information & communication | 2004 |
| Osborne Court Freehold Limited | Real estate | 2017 |
| Osborne Court Right to Manage Company Limited | Administrative & support | 2012 |
| Oswald Analytics Ltd | Information & communication | 2021 |
| OTA Labs Ltd | Information & communication | 2024 |
| Over & OUT Limited | Information & communication | 2012 |
| P Barton Ltd | Construction | 2018 |
| Paradice Ice Cream Parlour Limited | Wholesale & retail | 2018 |
| Pario Ventures Ltd | Professional & scientific | 2010 |
| Park Life Pictures Ltd | Information & communication | 2025 |
| Parsloe Consulting Limited | Professional & scientific | 2004 |
| Pawtected CIC | Education | 2021 |
| Pbrs Global Limited | Professional & scientific | 2026 |
| PCI Investment Ltd | Construction | 2019 |
| Pearls of Oriental (UK) Ltd | Hospitality | 2023 |
| Pemss Ltd | Construction | 2020 |
| Performance Boat Works Ltd | Manufacturing | 2017 |
| Petit Pois Productions Ltd | Arts & recreation | 2022 |
| Peto Limited | Information & communication | 2010 |
| Petrichor Planet Limited | Professional & scientific | 2021 |
| Pfds Consultancy Limited | Professional & scientific | 2018 |
| PH Svcs Ltd | Health & social care | 2020 |
| Photon Partners Limited | Professional & scientific | 2021 |
| Pierrepont Analysis Ltd | Professional & scientific | 2012 |
| Pinnyway Limited | Information & communication | 2026 |
| Pipeline Mechanical (IW) Ltd | Construction | 2026 |
| Pipeline Mechanical UK Ltd | Construction | 2017 |
| PJ Long Building Services Ltd | Construction | 2021 |
| Place Property Services Ltd | Real estate | 2023 |
| Plane Legal LLP | | 2009 |
| Plant an Oyster Ltd | Agriculture & fishing | 2022 |
| Pocket Full of Pebbles Ltd | Wholesale & retail | 2018 |
| Polymorph Capital Ltd | Professional & scientific | 2020 |
| Posh Laundry Limited | Extraterritorial | 2012 |
| Posh Pegs Limited | Manufacturing | 2006 |
| Power Plus Marine Ltd | Manufacturing | 2017 |
| Powersail Island Chandlery Limited | Wholesale & retail | 2000 |
| Ppex Limited | Information & communication | 2020 |
| Prickly Pear Kitchen Ltd | Hospitality | 2020 |
| Pride Southern Ltd | Construction | 2003 |
| Prime Residential Property Ltd | Real estate | 2024 |
| Priory Asset Group Holdings Ltd | Construction | 2019 |
| Priory Asset Investment Ltd | Construction | 2019 |
| Priory Asset Management LLP | | 2011 |
| Priory Assets Investment Ltd | Construction | 2019 |
| Priory Assets Management LLP | | 2011 |
| Priory Capital Investment Ltd | Construction | 2016 |
| Priory Cheshire (UK) Ltd | Construction | 2025 |
| Proiekto Limited | Professional & scientific | 2024 |
| Project IOW Limited | Construction | 2023 |
| Project Pilates Limited | Education | 2024 |
| Projects PJC Ltd | Professional & scientific | 2024 |
| Quantuit Ltd | Administrative & support | 2014 |
| R.B. Consultants IOW Ltd | Construction | 2025 |
| RAM Cat Ltd | Manufacturing | 2020 |
| Rashleys Premier Ltd | Wholesale & retail | 2022 |
| Ratsey & Lapthorn (Cowes) Limited | Manufacturing | 2010 |
| Ratsey Limited | Manufacturing | 2017 |
| RD Marine Electronics Ltd | Manufacturing | 2020 |
| RD Property Union Ltd | Real estate | 2022 |
| Real Estate Trade Products Limited | Manufacturing | 2026 |
| Red Ensign Limited | Administrative & support | 2005 |
| Red House Recruitment Ltd | Administrative & support | 2016 |
| Redg Rail Consulting Limited | Transport & logistics | 2021 |
| Redhead and Roberts Properties Limited | Construction | 2025 |
| Rees Advanced Marine Ltd. | Manufacturing | 2017 |
| Rena Grace Ltd | Hospitality | 2026 |
| Rethink Refresh Ltd | Education | 2023 |
| Retro Staycations Limited | Hospitality | 2021 |
| Reynolds EP Services Ltd | Education | 2024 |
| RFP Cowes (Isle of Wight) Ltd | Wholesale & retail | 2021 |
| RGS Services Ltd | Professional & scientific | 2020 |
| Rhue Light One Limited | Financial services | 2021 |
| Rise Loud CIC | Education | 2026 |
| Ritz Publications Limited | Information & communication | 2024 |
| RK FAB Welding Limited | Manufacturing | 2015 |
| Road and Racing Limited | Administrative & support | 2023 |
| Robsauven@Gmail.Com Ltd | Professional & scientific | 2024 |
| Rolias Health Investments Limited | Financial services | 2017 |
| Rosetta Consulting Ltd | Information & communication | 2016 |
| Rotapoint Limited | Real estate | 1989 |
| Route 66 UK Services Ltd | Other services | 2016 |
| Royal London Yacht Club Ltd | Arts & recreation | 2020 |
| Royal Yacht Squadron Ltd | Arts & recreation | 2014 |
| RP 334 Limited | Financial services | 2006 |
| Ryde Community Development Trust Ltd | Arts & recreation | 2017 |
| S D Fulford Holdings Ltd | Financial services | 2025 |