| THE Hull & East Yorkshire Medical Research Centre | Health & social care | 2000 |
| THE Hull and East Yorkshire Hospitals Health Charity | Health & social care | 2015 |
| THE Lemon Tree Day Nurseries Ltd | Education | 2013 |
| THE Life of Riley Appeal Limited | Health & social care | 2018 |
| THE Manor House Little Weighton Limited | Health & social care | 2018 |
| THE Ninith Development Ltd | Real estate | 2019 |
| THE Old Lamp Room Ltd | Wholesale & retail | 2019 |
| THE Old Vicarage Residential Care Home Limited | Health & social care | 2006 |
| THE Open Care Group Limited | Health & social care | 2019 |
| THE Orchard (Cottingham) Management Company Limited | Real estate | 2010 |
| THE Park Lane Healthcare Group Limited | Professional & scientific | 2018 |
| THE PIE Bakery Events Limited | Wholesale & retail | 2018 |
| THE PIE Weddings Limited | Wholesale & retail | 2018 |
| THE Platform Agency Ltd | Professional & scientific | 2023 |
| THE Retreat Thwaite Street Management Company Limited | Households | 2021 |
| THE Sensory Vault Ltd | Wholesale & retail | 2025 |
| THE Sloop Inn Limited | Hospitality | 2024 |
| THE Terracotta POT Company Ltd | Wholesale & retail | 2015 |
| THE Thomson Adventure Ltd | Arts & recreation | 2025 |
| THE Wheelie BIN Cleaning Company Limited | Other services | 2015 |
| Thearne Pet Stores & Kennels Limited | Wholesale & retail | 1960 |
| Therowleymanorhotelltd Ltd | Hospitality | 2024 |
| Thrive 360 Coaching Ltd | Administrative & support | 2025 |
| Thriving Futures Education Services Limited | Education | 2025 |
| Thurizza Limited | Health & social care | 2013 |
| Tidewood Property Ltd | Real estate | 2025 |
| TIG Bridal Limited | Wholesale & retail | 2020 |
| Tigers Logistics Limited | Transport & logistics | 2026 |
| Tigers Transport 1904 Ltd | Transport & logistics | 2025 |
| Tilbury Cast Stone Ltd | Manufacturing | 2023 |
| TIM Halford Electrical Services Limited | Construction | 2006 |
| Tinou Limited | Arts & recreation | 2025 |
| Tiresias Consulting Limited | Real estate | 2013 |
| Tironian Games Ltd | Information & communication | 2026 |
| TO2 Properties Ltd | Real estate | 2023 |
| Toccar Ltd | Wholesale & retail | 2025 |
| Todo Designs Ltd | Professional & scientific | 2020 |
| TOM Rice Bathrooms Ltd | Construction | 2021 |
| Tonhil Creations Ltd | Manufacturing | 2023 |
| Tony Dean (Consultancy) Limited | Professional & scientific | 2002 |
| Top Notch Sash Ltd | Construction | 2013 |
| Toys Tale Universe Limited | Wholesale & retail | 2025 |
| Train Taekwondo Limited | Arts & recreation | 2017 |
| Treadaway Training Services Ltd | Agriculture & fishing | 2024 |
| Trupower Limited | Professional & scientific | 2024 |
| Tusq Ltd | Administrative & support | 2021 |
| Typelosion UK Limited | Professional & scientific | 2017 |
| UK Leisure World Ltd | Wholesale & retail | 2015 |
| Ukanexcel Ltd | Information & communication | 2020 |
| Ulivo Management Services Ltd | Real estate | 2015 |
| Underdog Live Limited | Hospitality | 2022 |
| Uney App Ltd | Information & communication | 2018 |
| Unique Seal Services Limited | Professional & scientific | 2023 |
| Universal Cladding Limited | Construction | 2009 |
| Upgrade Electrical Ltd | Construction | 2020 |
| Urgroundsmaintenance Limited | Administrative & support | 2025 |
| Ursua Batin Property Ltd | Real estate | 2023 |
| Uson Perfusion Services Ltd | Health & social care | 2025 |
| Vanguard House Ltd | Professional & scientific | 2023 |
| Vantiklabs Limited | Information & communication | 2025 |
| Velvet Cactus Limited | Information & communication | 2024 |
| Vesta Assets Limited | Real estate | 2021 |
| Viboss Ltd | Other services | 2020 |
| Vicky Robinson Dance Company Ltd | Arts & recreation | 2026 |
| Viking Construction (Willerby) Limited | Construction | 2021 |
| VIP Creative Ltd | Professional & scientific | 2020 |
| VIP Matchdays Ltd | Other services | 2015 |
| Visabilo Digital Limited | Administrative & support | 2024 |
| Voight-Kampff Solutions Ltd | Information & communication | 2023 |
| W and C Property Group Ltd | Financial services | 2025 |
| Walk Civils Limited | Construction | 2025 |
| Waudby Developments Ltd | Real estate | 2026 |
| Waxandrelax Limited | Wholesale & retail | 2020 |
| Waypoint Group Limited | Information & communication | 2026 |
| WEH Enterprises Ltd | Financial services | 2017 |
| Welland Valley Cleans Ltd | Administrative & support | 2021 |
| Wellproof Company Limited | Real estate | 1993 |
| Westhaven Leisure Limited | Hospitality | 2018 |
| Westwood Property Investments Limited | Real estate | 2016 |
| Whitewoods Catering Limited | Hospitality | 2016 |
| Whole School Approach Ltd | Education | 2020 |
| Whyteclean Limited | Administrative & support | 2025 |
| Wild Candles of Yorkshire Ltd | Manufacturing | 2024 |
| Wildmoor Advisory Ltd | Professional & scientific | 2025 |
| Wildon Couriers UK Ltd | Transport & logistics | 2023 |
| Wildsteel Engineering Ltd | Manufacturing | 2026 |
| Wiles Holdings Limited | Financial services | 2008 |
| Willerby Plumbing and Heating Ltd | Construction | 2024 |
| Winterbottom Holdings Limited | Financial services | 2013 |
| WJK Solutions Ltd | Professional & scientific | 2025 |
| WK Holdings (Hull) Ltd | Real estate | 2025 |
| Wled Ltd | Manufacturing | 2022 |
| Wolds Way Holiday Cottages Limited | Real estate | 2022 |
| Wolf Shepherd Ltd | Professional & scientific | 2022 |
| Wood Electrical Services Limited | Construction | 2018 |
| Wood Fire Alarm Services Limited | Administrative & support | 2024 |
| Working for Health CIC | Health & social care | 2015 |
| Worldwide Transmissions (Hull) Limited | Wholesale & retail | 2015 |
| Wright Properties (Hull) Ltd | Real estate | 2013 |
| Write NOW Medical Limited | Professional & scientific | 2011 |