| Donellan Limited | Real estate | 2006 |
| Dorce Consulting Ltd | Professional & scientific | 2024 |
| Dose Bar and Lounge Ltd | Hospitality | 2026 |
| Dottx Ltd | Construction | 2023 |
| Double N Power Ltd | Transport & logistics | 2018 |
| DP Cars Solutions Ltd | Wholesale & retail | 2016 |
| DP Consulting Services Ltd | Professional & scientific | 2023 |
| DP Engineering Services Ltd | Manufacturing | 2024 |
| DP Logistics Services Ltd | Transport & logistics | 2022 |
| DPR Press Limited | Manufacturing | 2009 |
| DR Car Repair Limited | Wholesale & retail | 2023 |
| DR. FIX Limited | Construction | 2022 |
| Drag Car Services Ltd | Wholesale & retail | 2019 |
| Drage Electrics Limited | Construction | 1996 |
| Dragos D Ltd | Wholesale & retail | 2025 |
| Dream Baths Limited | Wholesale & retail | 2014 |
| Dreamwood Properties Limited | Real estate | 2020 |
| Drinkonomics Productions Limited | Professional & scientific | 2019 |
| Drivex Trucker Services Ltd | Transport & logistics | 2026 |
| DRK Management Limited | Arts & recreation | 2009 |
| Dropcore Solutions Ltd | Information & communication | 2026 |
| DS Body Repairs Ltd | Wholesale & retail | 2015 |
| DS2026 Ltd | Financial services | 2022 |
| Dsdl Investments Ltd | Real estate | 2019 |
| DTA Transport Ltd | Transport & logistics | 2015 |
| DTI LL SPV Ltd | Construction | 2024 |
| DTI Marketing Limited | | 1984 |
| Dualhealth Limited | Health & social care | 2014 |
| Duffield Store Ltd | Wholesale & retail | 2019 |
| Duffys Dining Ltd | Hospitality | 2026 |
| Dulca Construct Ltd | Construction | 2025 |
| Dumieez Signature Limited | Hospitality | 2025 |
| Dumpling Hood Ltd | Hospitality | 2023 |
| Dunkirk Developments Ltd | Administrative & support | 2017 |
| Durlum Leuchten Gesellschaft MIT Beschrankter Haftung Lichttechnische Spezialfabrik | | 2005 |
| Dwalden Engineering Limited | Professional & scientific | 2025 |
| Dwell-In Group of Companies Ltd | Health & social care | 2017 |
| Dwell-In Social Care Ltd | Health & social care | 2022 |
| Dwjw Roofing Ltd | Construction | 2025 |
| Dynamic Consultancy Services Ltd | Information & communication | 2022 |
| Dynamic Mind Limited | Other services | 2025 |
| Dyson Jones Holdings Limited | Financial services | 2020 |
| Dyson Jones Properties Limited | Real estate | 2020 |
| E and E Property Solutions Ltd | Real estate | 2019 |
| E Boat Logistics Ltd | Transport & logistics | 2019 |
| E N Evans Ltd | Extraterritorial | 2012 |
| E P Mills Roofing & Supplies Ltd. | Construction | 2018 |
| E&N Holdings Ltd | Real estate | 2025 |
| E&P Global Services Ltd | Information & communication | 2011 |
| E&R Real Estate Ltd | Hospitality | 2025 |
| E-Cont Automation Ltd | Manufacturing | 2026 |
| E.O.Marfo Limited | Administrative & support | 2017 |
| Eagle Corby Ltd | Hospitality | 2025 |
| Eagle Rise Homes Limited | Households | 2026 |
| Eagle's Nest Support Limited | Health & social care | 2022 |
| Eagles Development Ltd | Construction | 2026 |
| Early Years Business Support Ltd | Professional & scientific | 2024 |
| Earthgazer Limited | Manufacturing | 2000 |
| Eastern Industrial Properties Limited | Real estate | 2002 |
| Eastern Power and Motion Limited | Extraterritorial | 2021 |
| Easternrose Limited | Real estate | 2000 |
| Easy Cleaning Company Ltd | Administrative & support | 2025 |
| Easy Dwelling Group of Companies Ltd | Health & social care | 2017 |
| Easy Hands Ltd | Administrative & support | 2024 |
| Easyp 02 Limited | Real estate | 2025 |
| EASYP01 Ltd | Real estate | 2020 |
| EBA Refinish Ltd | Wholesale & retail | 2019 |
| Ebikeuk Ltd | Wholesale & retail | 2021 |
| EBM Electrical Services Limited | Construction | 2001 |
| Ebony Property Ventures Ltd | Real estate | 2024 |
| Echo Digital Limited | Information & communication | 2025 |
| Echo Packaging Limited | Manufacturing | 1992 |
| Eco Pride Contractors Limited | Construction | 2025 |
| Eco-Aqua Services Ltd | Construction | 2007 |
| Ecoser Ltd | Wholesale & retail | 2022 |
| Ecoshot Ltd | Manufacturing | 2022 |
| ECS Pubs Ltd | Hospitality | 2023 |
| ED Solomons Sporting Ltd | Wholesale & retail | 2025 |
| Edactive Ltd | Construction | 2020 |
| EDD Nino Esteban Recruitment Limited | Administrative & support | 2022 |
| Eden & EJ Homes Ltd | Real estate | 2018 |
| Eden DEW Housing CIC | Hospitality | 2019 |
| Eden Garden Projects Ltd | Administrative & support | 2023 |
| Edgar's Car Shop Ltd | Wholesale & retail | 2023 |
| Edgroup Holdings Ltd | Financial services | 2021 |
| Edmonds Properties Limited | Real estate | 2025 |
| Edpods Ltd | Construction | 2021 |
| Edsak Health Care Limited | Health & social care | 2014 |
| EDY Transport Services Ltd | Transport & logistics | 2025 |
| Efamy Company Limited | Manufacturing | 2005 |
| Efe's 01 Kebab Ltd | Hospitality | 2019 |
| Eight Care Providers Ltd | Health & social care | 2016 |
| Ejbio Ltd | Professional & scientific | 2022 |
| EJC Group Ltd | Health & social care | 2015 |
| EJT Capital Limited | Financial services | 2020 |
| EK Focus Ltd | Health & social care | 2024 |
| EKINS1 Limited | Real estate | 2019 |
| Elaine Famisaran Recruitment Limited | Administrative & support | 2023 |
| Eldar Financial Ltd | Professional & scientific | 2025 |
| Elec Cert Limited | Professional & scientific | 2008 |