| DE Beer Digital Ltd | Information & communication | 2021 |
| DE Havelland Developments Limited | Real estate | 2018 |
| DE Montecristo Enterprise Ltd | Professional & scientific | 2017 |
| DE Urban Estates Ltd | Real estate | 2026 |
| Debaith Properties Ltd | Real estate | 2024 |
| Debdale Technologies Limited | Wholesale & retail | 2009 |
| Deben Property Maintenance Services Ltd | Extraterritorial | 2016 |
| Debra Huzzard Limited | Professional & scientific | 2002 |
| Decades in Corby Ltd | Hospitality | 2019 |
| DECO27 Ltd | Wholesale & retail | 2025 |
| Decorum Cleaning Services Limited | Administrative & support | 2025 |
| DEE DOO Limited | Extraterritorial | 2004 |
| Deegits Technology Limited | Information & communication | 2023 |
| Deepcx Insights Ltd | Information & communication | 2022 |
| Defensor Security Services Limited | Administrative & support | 2025 |
| Define Data Limited | Real estate | 1995 |
| Defy Goliaths Ltd | Manufacturing | 2026 |
| Delightful Desserts Corby Ltd | Hospitality | 2025 |
| Dellah Care Limited | Health & social care | 2025 |
| Delta Polythene Limited | Extraterritorial | 1978 |
| Dely Speeds Transport Ltd | Transport & logistics | 2025 |
| Demodex Ltd | Construction | 2023 |
| Denraisa Limited | Transport & logistics | 2019 |
| Dent Tech Automotive Limited | Wholesale & retail | 2018 |
| Dentaverse Holdings Ltd | Financial services | 2022 |
| Derrys Associate Ltd | Construction | 2014 |
| Derrys Home Ltd | Real estate | 2024 |
| Desiree Seguritan Resource Limited | Administrative & support | 2023 |
| Desk Dealers Limited | Wholesale & retail | 2025 |
| Destino Dance Ltd | Other services | 2019 |
| Detafo INT Ltd | Health & social care | 2014 |
| Detection & Controls Ltd | Professional & scientific | 2020 |
| Deuce Hospitality Limited | Hospitality | 2021 |
| Devil’S Rock Publishing Limited | Information & communication | 2020 |
| Devonshire Consulting and Marketing Limited | Wholesale & retail | 1996 |
| Devotion Integrated Care Ltd | Public administration | 2018 |
| Devout Healthcare Ltd | Health & social care | 2022 |
| DF Final Touch Ltd | Construction | 2016 |
| DF Spedition Ltd | Transport & logistics | 2025 |
| DFD Care and Support Services Ltd | Health & social care | 2019 |
| DFP Sports Ltd | Arts & recreation | 2015 |
| DGG Commercials Ltd | Wholesale & retail | 2023 |
| DGM Electrical Services Ltd | Manufacturing | 2016 |
| Dhex Ltd | Information & communication | 2026 |
| DIA Construction Ltd | Construction | 2018 |
| Diag Demon Ltd | Wholesale & retail | 2025 |
| Dialect SPV Ltd | Real estate | 2023 |
| Diamond London Perfume Ltd | Wholesale & retail | 2025 |
| Diamond Social Care Solution's Ltd | Public administration | 2023 |
| Diamond Street Services Ltd | Administrative & support | 2016 |
| Diamond Windscreens Limited | Wholesale & retail | 2003 |
| Diel Logistic Ltd | Transport & logistics | 2024 |
| Digit Tape Limited | Wholesale & retail | 2022 |
| Digital Systems & Service Limited | Other services | 2002 |
| Dilsak Limited | Real estate | 2000 |
| Dimattiaproperties Ltd | Real estate | 2023 |
| Dimol Transport Ltd | Transport & logistics | 2014 |
| Dimond Recovery Ltd | Wholesale & retail | 2025 |
| Dinforty Ltd | Construction | 2026 |
| Dinsormaintenance Limited | Construction | 2025 |
| Direct Payments Payroll Service Limited | Administrative & support | 1996 |
| Directfleet National Ltd | Transport & logistics | 2025 |
| Display Box Ltd | Wholesale & retail | 2024 |
| Display Mode Limited | Manufacturing | 2009 |
| Distinct Fitness Ltd | Arts & recreation | 2024 |
| Distinct Workwear Ltd | Wholesale & retail | 2020 |
| Distinction Kitchens Ltd | Construction | 2017 |
| District International Limited | Other services | 2018 |
| Ditchford Electric Motors Limited | Manufacturing | 2023 |
| Ditchford Limited | Other services | 2022 |
| Diverse Technical Services Limited | Administrative & support | 2005 |
| Diversecentrecare Ltd | Health & social care | 2022 |
| Divine Journeys Limited | Administrative & support | 2020 |
| Divine MED Ltd | Health & social care | 2019 |
| Divine Physiotherapy Limited | Health & social care | 2013 |
| Divine Twins Ltd | Health & social care | 2019 |
| Diygarage Limited | Wholesale & retail | 2025 |
| Diynu Ltd | Transport & logistics | 2019 |
| Djk-Greg Limited | Manufacturing | 2014 |
| DK Commercials Limited | Extraterritorial | 2012 |
| DKJ (Holdings) Limited | Real estate | 2001 |
| DKP Estates Limited | Real estate | 2025 |
| DM Employee Ownership Trustee Limited | Professional & scientific | 2020 |
| DM Weston Consulting Ltd | Professional & scientific | 2025 |
| DMB & Go Ltd | Transport & logistics | 2024 |
| DMJ Trans Ltd | Transport & logistics | 2021 |
| DML Global Ltd | Wholesale & retail | 2026 |
| DNA Father and Son's Electrical Ltd | Construction | 2020 |
| DNA Power Solutions Limited | Extraterritorial | 2025 |
| Dncc Constructions Ltd | Construction | 2025 |
| DNY Solutions Ltd | Wholesale & retail | 2024 |
| DO Quick Couriers Ltd | Transport & logistics | 2021 |
| Dobos Construction Limited | Construction | 2016 |
| DOC Plumbing and Heating Ltd | Construction | 2015 |
| Doek Festival Community Network CIC | Arts & recreation | 2026 |
| Dolby Express Deliveries Limited | Transport & logistics | 2001 |
| DOM Fast Trans Ltd | Transport & logistics | 2026 |
| Domalenco Ltd | Professional & scientific | 2012 |
| Domus Lignea Restoration Ltd | Manufacturing | 2021 |
| DON Millers (Wellingborough) Limited | Wholesale & retail | 2009 |