| Right Track Accounts Limited | Professional & scientific | 2020 |
| Right Track Integrated Business Services Limited | Professional & scientific | 2010 |
| Rimontgo Limited | Professional & scientific | 2011 |
| Rimple Limited | Professional & scientific | 2013 |
| Riverrock Holdings Limited | Information & communication | 2016 |
| Riverside Park Limited | Construction | 2002 |
| Rivion Group Ltd | Professional & scientific | 2025 |
| RJ Asset Management Ltd | Financial services | 2023 |
| RJH Car Sales Ltd | Wholesale & retail | 2017 |
| RL21 Ltd | Wholesale & retail | 2021 |
| RLD Healthcare Ltd | Health & social care | 2022 |
| ROB Moors Consulting Ltd | Professional & scientific | 2020 |
| Robcam Limited | Real estate | 2021 |
| Robert Brennan Corporate Ltd | Professional & scientific | 2022 |
| Robert Brennan UK Limited | Education | 2010 |
| Roblescarecompany Limited | Health & social care | 2016 |
| Rock Merchanting Limited | Manufacturing | 1959 |
| Rode Heath Properties Ltd | Real estate | 1981 |
| ROE 2015 Limited | Extraterritorial | 2015 |
| Roland Co (NW) Limited | Financial services | 2025 |
| Roman Consulting Ltd | Professional & scientific | 2024 |
| Rood Hill Property Limited | Real estate | 2015 |
| Roofs R US (Congleton) Ltd | Construction | 2025 |
| Rookery Farm Developments Ltd | Construction | 2025 |
| Rookery Farm Partnership Ltd | Real estate | 2025 |
| Room 303 Ltd | Professional & scientific | 2023 |
| Roost Technologies Ltd | Information & communication | 2026 |
| Root TRA Ltd | Professional & scientific | 2025 |
| Rope Access Assist Ltd | Water & waste | 2014 |
| Rose Sienna Limited | Hospitality | 2024 |
| Rosie Rentals Ltd | Real estate | 2021 |
| Rostherne Research Ltd | Information & communication | 2024 |
| Rotawatch Limited | Information & communication | 2014 |
| Rotric Hennan Automotive Ltd | Wholesale & retail | 2024 |
| Rouban Birch Dog Training Ltd | Other services | 2026 |
| Rough HEY Limited | Construction | 2005 |
| Route Robin Ltd | Manufacturing | 2026 |
| Rowarth Civils Ltd | Construction | 2013 |
| Rowe Deliveries Ltd | Transport & logistics | 2019 |
| Rowley Brothers Property Limited | Construction | 2015 |
| Rowtype Printers (Holdings) Ltd | Manufacturing | 2024 |
| Royle Street Beds & Sofas Ltd | Wholesale & retail | 2021 |
| Royles Beds & Furnishings Ltd | Wholesale & retail | 2021 |
| Royles Beds Ltd | Wholesale & retail | 2025 |
| RP Apex Ltd | Professional & scientific | 2024 |
| RP Construction Design Ltd | Construction | 2022 |
| RPB Construction Ltd | Professional & scientific | 2026 |
| RPM88 Ltd | Professional & scientific | 2026 |
| RR Medicolegal Consultancy Limited | Health & social care | 2018 |
| Rrll Property Ltd | Real estate | 2023 |
| RS Fire & Security Ltd | Administrative & support | 2022 |
| RS Grounds and Estates Ltd | Administrative & support | 2025 |
| Ruby One Ltd. | Professional & scientific | 2013 |
| Ruby's Fund | Arts & recreation | 2013 |
| Runaway Pictures Limited | Information & communication | 2010 |
| Runwell Enterprises Ltd | Financial services | 1997 |
| Rural Heating Services Ltd | Construction | 2018 |
| Rushey HEY Ltd | Construction | 2013 |
| Rushton Limited | Professional & scientific | 1993 |
| Rushton Pet & Poultry Housing Limited | Manufacturing | 2003 |
| Russell Beeden Limited | Information & communication | 2010 |
| Rustica Limited | Hospitality | 2024 |
| RV Partners Ltd | Professional & scientific | 2024 |
| RX Property Group Ltd | Real estate | 2025 |
| Ry-Fi UK Limited | Professional & scientific | 2020 |
| S a Bell (West Heath) Limited | Wholesale & retail | 2004 |
| S Bar & Nightclub Ltd | Hospitality | 2026 |
| S J Forrester Construction Ltd | Construction | 2025 |
| S K B Leisure Limited | Wholesale & retail | 2021 |
| S Price & Co Ltd | Professional & scientific | 2005 |
| S W Wines Ltd | Wholesale & retail | 2012 |
| S.D.G Electric Ltd | Manufacturing | 2018 |
| S.R.Allen & Sons Limited | Real estate | 1927 |
| S.R.Taylor.Heating and Plumbing Limited | Construction | 2006 |
| S3 Security Services Ltd | Administrative & support | 2006 |
| Sacred Nature Fine Furniture Ltd | Manufacturing | 2020 |
| Sacred Nature Furniture Ltd | Manufacturing | 2026 |
| Sadhana Cheshire Limited | Health & social care | 2026 |
| Safa's Collections Ltd | Wholesale & retail | 2024 |
| Safe Places for Children Secretariat | Health & social care | 2016 |
| Safe Places for Children UK | Health & social care | 2016 |
| Safeguard World International Holdings Limited | Professional & scientific | 2015 |
| Safeguard World International Limited | Financial services | 2007 |
| Safeline Distribution Ltd | Transport & logistics | 2019 |
| Safety PAT Ltd | Professional & scientific | 2013 |
| Safety Screens Limited | Manufacturing | 1989 |
| Sagezander Ltd | Wholesale & retail | 2006 |
| Saha Ventures Ltd | Wholesale & retail | 2020 |
| Saighton Limited | Professional & scientific | 2010 |
| SAK Innovations Ltd | Wholesale & retail | 2023 |
| Sakura Living Ltd | Hospitality | 2026 |
| Saleable Property and Gardens Limited | Construction | 2013 |
| Sales Management Associates Limited | Professional & scientific | 2017 |
| Salon 29 Ltd | Other services | 2009 |
| Salon Sisters Limited | Other services | 2025 |
| Salveo Bodycare Ltd | Health & social care | 2014 |
| SAM Plaire Limited | Construction | 2009 |
| SAM Scaffolding North West Ltd | Construction | 2023 |
| Sam's Joinery Ltd | Construction | 2019 |
| Samkoman Consulting Limited | Professional & scientific | 2009 |