| Dbfd Ltd | Professional & scientific | 2021 |
| DC Design Flooring Ltd | Wholesale & retail | 2021 |
| DCO Systems Ltd | Manufacturing | 2016 |
| DE Metz Forbes Knight Architects Limited | Construction | 1999 |
| Decaf Coffee Club Ltd | Manufacturing | 2023 |
| Decima Medical Ltd | Manufacturing | 2026 |
| Deli Events Limited | Hospitality | 2026 |
| Delmor Ltd | Real estate | 2022 |
| Denarius Partnership Ltd | Professional & scientific | 2016 |
| Dentablue Ltd | Manufacturing | 2025 |
| Derek Raphael & Company Limited | Wholesale & retail | 1973 |
| Derek Raphael & Company Trustees Limited | Professional & scientific | 1995 |
| Derek Raphael (Holdings) Limited | Professional & scientific | 1985 |
| Derham Property Ltd | Real estate | 2025 |
| Dernahatten Limited | Information & communication | 2024 |
| Derrick Francis Masonry Limited | Manufacturing | 2016 |
| Derry Consultants Ltd | Professional & scientific | 2015 |
| Design Concept Works Ltd | Professional & scientific | 2025 |
| Design I.Q. Limited | Administrative & support | 1999 |
| Designrock Limited | Professional & scientific | 2007 |
| Designs by Limited | Administrative & support | 2016 |
| Dessna Company Limited | Water & waste | 1997 |
| Detailing Supplies Ltd | Administrative & support | 2013 |
| DHP Capital Holdings Limited | Financial services | 2025 |
| DHP Nexus Solutions Limited | Information & communication | 2013 |
| DHP Property Solutions Ltd | Real estate | 2022 |
| DHS Technologies Limited | Information & communication | 2025 |
| Diarybooker.Com Limited | Information & communication | 2010 |
| Digital Healthtech Ltd | Wholesale & retail | 2022 |
| Digup Limited | Information & communication | 2017 |
| Dijer Limited | Professional & scientific | 2012 |
| Dillonandi Ltd | Manufacturing | 2022 |
| Dine & Slumber Ltd | Hospitality | 2020 |
| Diverseaction Limited | Administrative & support | 2024 |
| DJ Property Estates Limited | Real estate | 2022 |
| Djbvt Ltd | Professional & scientific | 2018 |
| DJH Civil Design Limited | Professional & scientific | 2007 |
| DJH Estates Management Services Ltd | Professional & scientific | 2024 |
| DJH Global Ltd | Professional & scientific | 2019 |
| Djthomas Limited | Construction | 2017 |
| DK52 Limited | Arts & recreation | 2013 |
| DKR Properties Ltd | Real estate | 2021 |
| DL Developments Building and Landscaping Ltd | Construction | 2025 |
| Dlmm Properties Ltd | Real estate | 2024 |
| DM Focus Group Limited | Other services | 2021 |
| DM Focus Limited | Other services | 2004 |
| DM Focus Lists Limited | Other services | 2021 |
| DMH Cirencester Limited | Wholesale & retail | 2001 |
| DMS Agency Services Ltd | Financial services | 1999 |
| DMS Property Renovation Ltd | Water & waste | 2011 |
| Docklow Manor Farm Holiday Centre Limited | Hospitality | 1979 |
| Docleaf Advisory Services Limited | Financial services | 2009 |
| Dodd Enterprises Ltd | Wholesale & retail | 2020 |
| Dodd Investment Holdings Ltd | Real estate | 2021 |
| Doggett & Edwards Ltd | Hospitality | 2019 |
| Dolcetti (Cotswolds) Limited | Manufacturing | 2025 |
| Dolcetti Events Limited | Manufacturing | 2026 |
| Dolcetti Ice Cream Company Limited | Manufacturing | 2012 |
| Dolci DI Lechlade Ltd | Wholesale & retail | 2015 |
| Domicilia Limited | Households | 1998 |
| Dominic ASH Ltd | Administrative & support | 2003 |
| DON Pelayox Ltd | Professional & scientific | 2015 |
| Donkeywell Farm Limited | Agriculture & fishing | 2025 |
| Donkeywell Forge Ltd | Manufacturing | 2016 |
| Donkeywell Lettings Limited | Real estate | 2025 |
| Donkeywell LLP | | 2012 |
| DOOR5 Studios Ltd | Information & communication | 2024 |
| Dorfold Cripps Ltd | Hospitality | 2020 |
| Double R Barbershop Ltd | Other services | 2021 |
| Double S Consultancy Limited | Professional & scientific | 2017 |
| Double Son's Ltd | Professional & scientific | 2023 |
| Doubler Marketing Ltd | Professional & scientific | 2023 |
| Doubler Services Ltd | Hospitality | 2022 |
| Douglas Moule Services Ltd | Professional & scientific | 2024 |
| Dovecote Cottage Ltd | Hospitality | 2015 |
| Dower Court (Somerford Keynes) Management Company Limited | Households | 1991 |
| Dowman Imports Limited | Wholesale & retail | 1988 |
| Down Ampney House Ltd | Administrative & support | 2024 |
| Down to Earth Garden Maintenance Ltd | Administrative & support | 2005 |
| DPM Stoves and Chimney Sweep Ltd | Administrative & support | 2019 |
| DR Lauren Mcpartlan Clinical Psychology Limited | Health & social care | 2021 |
| DR Leigh Neal & Associates Limited | Health & social care | 2024 |
| Drain Repair Services Limited | Water & waste | 2024 |
| Drake Images Limited | Professional & scientific | 2013 |
| Draycott Collective Ltd | Information & communication | 2026 |
| Draycott Garage Ltd | Wholesale & retail | 2014 |
| Draycott Property Limited | Real estate | 2026 |
| DRC Properties Limited | Real estate | 1995 |
| Dream Team Television Limited | Information & communication | 1994 |
| Drift Pictures Ltd | Information & communication | 2024 |
| Droodle Ltd | Wholesale & retail | 2024 |
| Dryffe Projects Limited | Professional & scientific | 2017 |
| DSG Global Risk Management Limited | Administrative & support | 2019 |
| DSG Risk & Facilities Management Limited | Administrative & support | 2025 |
| DSTRKT33 Limited | Information & communication | 2022 |
| Dubens Properties Limited | Professional & scientific | 1964 |
| Dudman Electrical Services Ltd | Construction | 2013 |
| DW Dunn Holdings Ltd | Financial services | 2023 |
| DW Dunn Properties Ltd | Administrative & support | 2023 |
| DWP Services Limited | Construction | 2016 |