| Sukhman Limited | Wholesale & retail | 2021 |
| Sukhmanni Properties Ltd | Real estate | 2024 |
| Sumark Holdings Limited | Real estate | 2023 |
| Sumit Roofing Solutions Limited | Construction | 2019 |
| Summer House Express Ltd | Hospitality | 2024 |
| Summit Building and Electrical Services Ltd | Construction | 2025 |
| Summit Integrated Care Solutions Ltd | Health & social care | 2026 |
| Summits Business Solutions Limited | Administrative & support | 2020 |
| Sumo Sleep Ltd | Wholesale & retail | 2019 |
| Sundell Corporation Limited | Wholesale & retail | 2018 |
| Sunningdale (Whittle LE Woods) Management Company Limited | Households | 2008 |
| SUNNYMOUNTAIN1871 Ltd | Wholesale & retail | 2026 |
| Sunnyside House (Woolacombe) Management Ltd | Real estate | 2026 |
| Super Bits Ltd | Wholesale & retail | 2022 |
| Super Hand Car Wash Chorley Ltd | Administrative & support | 2020 |
| Super Market 38 Ltd | Wholesale & retail | 2025 |
| Super-Me Fitness Ltd | Arts & recreation | 2020 |
| Supercigs Ltd | Wholesale & retail | 2026 |
| Superior PIC Limited | Administrative & support | 2019 |
| Superlite Motorsport Limited | Manufacturing | 2018 |
| Supremesourcing Ltd | Administrative & support | 2026 |
| SURE2 Media Ltd | Information & communication | 2021 |
| Surebuy Corporate Services Limited | Administrative & support | 2019 |
| Surebuy Limited | Administrative & support | 2019 |
| Surefit Fitted Furniture Ltd | Manufacturing | 2021 |
| Sureway Windows Ltd | Construction | 2014 |
| Surpro Limited | Manufacturing | 2012 |
| Surrey Financial Consultants Limited | Professional & scientific | 2003 |
| Susan Craig Bridalwear Ltd | Wholesale & retail | 2009 |
| Susan Ross Accountancy and Bookkeeping Services Limited | Professional & scientific | 2014 |
| Sutton House (Cheshire) Ltd | Health & social care | 2025 |
| Sutton Motor Services Limited | Wholesale & retail | 1994 |
| Suzrew Enterprise Limited | Health & social care | 2012 |
| SV Legal Training Limited | Education | 2013 |
| SVC the Label Limited | Wholesale & retail | 2024 |
| SVD Management Ltd | Hospitality | 2023 |
| Sverre Ltd | Wholesale & retail | 2019 |
| SVG Installations Ltd | Construction | 2025 |
| SW Tech Limited | Professional & scientific | 2025 |
| Swallow Office Supplies Limited | Wholesale & retail | 2014 |
| Swallowtail Financial Consulting Limited | Professional & scientific | 2021 |
| Swanlow Lane Ltd | Real estate | 2026 |
| Swapchain Limited | Extraterritorial | 2003 |
| Swat Access Limited | Administrative & support | 2010 |
| Swdesign Ltd | Professional & scientific | 2019 |
| Sweeper Hire Ltd | Administrative & support | 2003 |
| Sweet & Shop Limited | Wholesale & retail | 2025 |
| Sweet AI Ltd | Manufacturing | 2023 |
| Sweet Mama Bakes Ltd | Manufacturing | 2022 |
| Sweet N Chilly Ltd | Hospitality | 2023 |
| Sweetcow Investments Ltd | Real estate | 2018 |
| Swidham Ltd | Health & social care | 2014 |
| Swift Legal Consultancy Ltd | Other services | 2022 |
| Swift Property Connections Ltd | Real estate | 2026 |
| Swift Serve (Yorkshire) Limited | Administrative & support | 2026 |
| Swift T&T Ltd | Transport & logistics | 2022 |
| Swift Turner Round Ltd | Real estate | 2017 |
| Swiftsales Hub Ltd | Wholesale & retail | 2025 |
| Swim Advance Ltd | Education | 2019 |
| Swim Cosy Limited | Wholesale & retail | 2022 |
| Swoosh Services Ltd | Administrative & support | 2025 |
| SYC 2020 Ltd | Construction | 2020 |
| Sycamore Corporation Limited | Professional & scientific | 2019 |
| Sycamore House Trading & Services Limited | Administrative & support | 2018 |
| SYD Brown and Sons Limited | Extraterritorial | 1965 |
| Sykes Specialist Contracting Limited | Construction | 2006 |
| Symagroup Ltd | Manufacturing | 2020 |
| Symnetic Ltd | Administrative & support | 2023 |
| Symposium Ventures Limited | Hospitality | 2018 |
| Synergy Assist Limited | Administrative & support | 2025 |
| Synergy Cooling Limited | Professional & scientific | 2023 |
| Synergy Research Limited | Extraterritorial | 2013 |
| Sysi Services Ltd | Real estate | 2018 |
| Systematic Instruments Limited | Administrative & support | 2009 |
| Systemhost Limited | Information & communication | 2004 |
| SZ Chorley Limited | Hospitality | 2018 |
| T & a Consultancy Limited | Professional & scientific | 2018 |
| T & D Stevenson Ltd | Real estate | 2006 |
| T & G Building Contracts Ltd. | Construction | 2019 |
| T a Jones Properties Limited | Real estate | 2017 |
| T Ashworth Limited | Information & communication | 2015 |
| T Cooke HGV Ltd | Transport & logistics | 2026 |
| T D TAZ Ltd | Construction | 2026 |
| T H a Consulting Limited | Information & communication | 2015 |
| T J Home Comforts Ltd | Wholesale & retail | 2022 |
| T L - Sting (UK) Limited | Wholesale & retail | 2011 |
| T M T Trucking Limited | Transport & logistics | 2013 |
| T Medics Ltd | Health & social care | 2017 |
| T P Johnson Ltd | Wholesale & retail | 2021 |
| T Square Interior Solutions Limited | Construction | 2018 |
| T Sumner Smith Ltd. | Professional & scientific | 2000 |
| T W Estates (Northern) Ltd | Real estate | 2017 |
| T W Leisure Limited | Wholesale & retail | 2014 |
| T&E Logistics Ltd | Transport & logistics | 2025 |
| T&F Construction Services Ltd | Construction | 2024 |
| T&J Davies Joinery and Build Ltd | Construction | 2024 |
| T. Georgeson Haulage Ltd | Transport & logistics | 2020 |
| T. Jones Ltd. | Construction | 1988 |
| T.P.D. (Lancs) Limited | Professional & scientific | 2000 |
| T.R & Daughters Ltd | Transport & logistics | 2025 |