| D.S. Signs & Graphics Limited | Professional & scientific | 2007 |
| D3 Capital Holdings Ltd | Financial services | 2026 |
| D3 Productions Ltd | Arts & recreation | 2022 |
| DA Design Automation Ltd | Manufacturing | 1998 |
| DA Techs (NW) Limited | Wholesale & retail | 2016 |
| DA Techs (UK) Ltd | Wholesale & retail | 2020 |
| Daawood Limited | Professional & scientific | 2005 |
| Dabbling Duck Limited | Professional & scientific | 2022 |
| DAC Building Services Ltd | Construction | 2022 |
| Dache Plastering Ltd | Construction | 2017 |
| Dadswell Property Management Limited | Households | 2019 |
| Dainton J Limited | Wholesale & retail | 2018 |
| Daisy Takeaway Ltd | Hospitality | 2022 |
| Daizymc Ltd | Transport & logistics | 2021 |
| Dajk Investments Limited | Real estate | 2021 |
| Dakar Leisure Ltd. | Hospitality | 1997 |
| DAL Electrical Ltd | Construction | 2014 |
| Dalepeak Limited | Administrative & support | 1998 |
| Dales Logistics Limited | Transport & logistics | 2019 |
| Dales Transport Ltd | Administrative & support | 2017 |
| Dalss LLP | | 2013 |
| Dalss NO 1 Limited | Real estate | 2018 |
| DAN Nevin Logistics Ltd | Transport & logistics | 2025 |
| Dance Nation Promotions Limited | Arts & recreation | 2020 |
| Dancefloor Couture Ltd | Administrative & support | 2011 |
| Dandar Properties Ltd | Real estate | 2020 |
| Dane Clarke Joinery Ltd | Manufacturing | 2019 |
| Daniel Hawksey Transport Ltd | Transport & logistics | 2017 |
| Daniel Mort Construction Limited | Construction | 2011 |
| Daniel Transport NW Ltd | Transport & logistics | 2024 |
| Daniel Yarrow Properties Ltd | Real estate | 2018 |
| Dantys Bites Limited | Hospitality | 2024 |
| Dara Consulting Ltd | Information & communication | 2019 |
| Dara Lake Limited | Wholesale & retail | 2019 |
| Darcie Solutions Limited | Transport & logistics | 2010 |
| Dare 2 DO Ltd | Transport & logistics | 2012 |
| Dark Lane Fitness Limited | Arts & recreation | 2014 |
| Dark Magic Prints Ltd | Wholesale & retail | 2024 |
| Dark Matter Agency Ltd | Information & communication | 2021 |
| Dark Secrets Hair Part II Limited | Other services | 2012 |
| Darktech Ltd | Professional & scientific | 2022 |
| Darren P Skarratt Limited | Construction | 2016 |
| Darsan Property Ltd | Real estate | 2025 |
| Daruma Limited | Hospitality | 2011 |
| Darwen Plumbing and Drains Services Ltd | Construction | 2019 |
| Darwin Jones Developments Ltd | Construction | 2026 |
| Dashmas Limited | Health & social care | 2022 |
| Data Sciences UK (MN) Limited | Wholesale & retail | 2011 |
| Datp Limited | Administrative & support | 2014 |
| Daubney Security Ltd | Construction | 2018 |
| Dauntsey Building Plastics Limited | Construction | 2011 |
| DAV MAK Care Solutions Ltd | Administrative & support | 2017 |
| Dave Ashu Transport Ltd | Transport & logistics | 2017 |
| Dave Eyes Ltd | Wholesale & retail | 2022 |
| Davenport Optical Ltd | Wholesale & retail | 2020 |
| David Hull Gardening Services Limited | Administrative & support | 2015 |
| David J. Killen & Co. (Insurance Services) Limited | Financial services | 1989 |
| David Lyles Transport Limited | Transport & logistics | 2017 |
| David O'Byrne Ltd | Professional & scientific | 2022 |
| David Taylor Holdings Limited | Financial services | 2020 |
| David Urquhart Holidays Limited | Administrative & support | 2020 |
| Davinia Taylor Limited | Health & social care | 2020 |
| Davlyn Fleet Maintenance Ltd | Manufacturing | 2019 |
| DAW Renovations Ltd | Construction | 2026 |
| Daxda Limited | Information & communication | 2010 |
| Day Estates Limited | Real estate | 2024 |
| Daynor Construction Services Limited | Construction | 2011 |
| DB Lifting Services Ltd | Construction | 2026 |
| DB Search Solutions Ltd | Administrative & support | 2017 |
| DB Tiling Ltd | Construction | 2025 |
| Dbbol Holdings Ltd | Financial services | 2026 |
| DBT Transport Limited | Administrative & support | 2012 |
| Dbtm Consultancy Services Ltd | Construction | 2017 |
| DC Leisure Ltd | Hospitality | 2025 |
| DCR Delivery Ltd | Construction | 2021 |
| DD Chorley Ltd | Wholesale & retail | 2025 |
| DDJ Design Ltd | Professional & scientific | 2021 |
| DDR Developments Limited | Real estate | 2021 |
| DE Cuba Habana Limited | Hospitality | 2018 |
| DE Silva Hypnotherapy Limited | Health & social care | 2017 |
| Dead Body Customs Ltd | Wholesale & retail | 2025 |
| Deakin & White (Long Eaton) Limited | Other services | 2016 |
| Deakin's Developments NW Limited | Real estate | 2024 |
| Dealersense Limited | Households | 1993 |
| Dean Rental Hub Limited | Real estate | 2024 |
| Deane Motors Ltd | Wholesale & retail | 2003 |
| Dearne Valley Foodservice Limited | Wholesale & retail | 2012 |
| Deborah Stead Therapeutic Training Limited | Health & social care | 2020 |
| Debra Hesford Q a Services Ltd | Health & social care | 2019 |
| Decalheads Limited | Wholesale & retail | 2011 |
| Deceduto Coffee Company Ltd | Hospitality | 2016 |
| Deckking Limited | Construction | 2004 |
| Decor Home Improvements Ltd | Construction | 2018 |
| Dedicated 2 Sport Limited | Administrative & support | 1994 |
| Defg Trading Limited | Wholesale & retail | 2022 |
| Defined Water Treatment Solutions Ltd | Water & waste | 2014 |
| Defne Leaves Limited | Administrative & support | 2021 |
| Delacruz Ltd | Information & communication | 2017 |
| Delamere Group Ltd | Real estate | 2017 |
| Delaney Design & Development Ltd | Construction | 2022 |