| Elite Sculling Ltd | Education | 2020 |
| Elite Snowsports Limited | Wholesale & retail | 2021 |
| Elite Spices Ltd | Hospitality | 2023 |
| Eliteline Ltd | Transport & logistics | 2025 |
| Elitesafe Consulting Ltd | Professional & scientific | 2025 |
| Elixir Corporate Limited | Professional & scientific | 2006 |
| Eliza Fricker Ltd | Information & communication | 2024 |
| Elizabeth Miles Design Limited | Wholesale & retail | 2018 |
| Elland Estates Limited | Real estate | 2012 |
| Ellen Marketing Ltd | Professional & scientific | 2023 |
| Ellerston Polo Limited | Arts & recreation | 2026 |
| Elliotts Caravan Estates Limited | Hospitality | 1954 |
| Ellis Property Managment Ltd | Construction | 2008 |
| Ellscott Park Limited | Hospitality | 2002 |
| Ellsworth Investment Co.(The) | Real estate | 1953 |
| ELM Isle Ltd | Construction | 2025 |
| Elmer Grange Management Co. Limited | Administrative & support | 1986 |
| Elmers Cafe Ltd | Hospitality | 2025 |
| Elms Crescent Freehold Limited | Households | 2011 |
| Elms Way and Meadow Lane Residents Association Limited | Households | 1972 |
| Elmwood Property Solutions Ltd | Other services | 2025 |
| Eloquent INK Writing Services Limited | Professional & scientific | 2015 |
| ELS Marketing Limited | Information & communication | 2024 |
| Elsinore Nominees Limited | Professional & scientific | 2000 |
| Eluxevo Limited | Manufacturing | 2022 |
| Ember Sales Ltd | Professional & scientific | 2023 |
| Embracing Nutrition Limited | Health & social care | 2011 |
| Emca Engineering Ltd | Construction | 2011 |
| Emerald Fundraising U.K. Limited | Wholesale & retail | 2025 |
| Emerge Mhealth Ltd | Health & social care | 2019 |
| Emma Perring Design Limited | Real estate | 1990 |
| Emma Pinder Architects Limited | Professional & scientific | 2015 |
| Emma Red Limited | Other services | 2006 |
| Emma Stride Limited | Professional & scientific | 2003 |
| Emmanuel International Limited | Health & social care | 1984 |
| Empactis (IPR) Limited | Administrative & support | 2005 |
| Empactis Limited | Information & communication | 2001 |
| Empire Creative Ltd | Wholesale & retail | 2022 |
| Empire Welding Supplies Limited | Wholesale & retail | 1988 |
| Employer LED Skills Limited | Professional & scientific | 2013 |
| Empx Ltd | Information & communication | 2023 |
| Emqv Ltd | Information & communication | 2023 |
| Emrose Limited | Administrative & support | 1995 |
| Emsbourne Developments Ltd | Construction | 2006 |
| Emsworth Delicatessen Ltd | Wholesale & retail | 2011 |
| Emsworth Laundry Limited | Financial services | 1949 |
| Emunet Limited | Information & communication | 2013 |
| Enable and Thrive Limited | Health & social care | 2017 |
| Enardepy Limited | Information & communication | 2013 |
| Enborne Properties Limited | Real estate | 1994 |
| Encompass Plumbing & Heating Ltd. | Construction | 2005 |
| Encore Software Ltd | Information & communication | 2020 |
| END of Life Network CIC | Education | 2025 |
| Endeavour Sustainably Consultancy Limited | Professional & scientific | 2026 |
| Endure Building Design Limited | Professional & scientific | 2018 |
| Energy Matters Nationwide Limited | Professional & scientific | 2009 |
| Energy TEC Services Ltd | Construction | 2023 |
| Energyscan Limited | Professional & scientific | 2004 |
| Enetic Associates Ltd | Administrative & support | 2025 |
| Enetic Solutions Ltd | Professional & scientific | 2025 |
| Enetic Utilities Ltd | Administrative & support | 2025 |
| ENG Applestore Ltd | Construction | 2025 |
| Engage Process UK Ltd | Information & communication | 2019 |
| Engage Train Support Limited | Education | 2023 |
| Engineer Aftercare Ltd | Wholesale & retail | 2019 |
| Engreena Ltd | Manufacturing | 2025 |
| Enhanced View Ultrasound Ltd | Health & social care | 2026 |
| Enigmania Limited | Arts & recreation | 1987 |
| Enjoy Precious Moments Ltd | Manufacturing | 2021 |
| Enrobria Ltd | Information & communication | 2021 |
| Enso Psychology Ltd | Health & social care | 2025 |
| Enterprise Engineering Limited | Hospitality | 2018 |
| Enterprising Solutions Ltd | Financial services | 2019 |
| Entheos Enterprise Limited | Manufacturing | 2005 |
| Entheos Holdings Limited | Professional & scientific | 1990 |
| Entheos Newco 3 Limited | Administrative & support | 2011 |
| Envi Systems Limited | Construction | 2017 |
| Enviromonitors Limited | Professional & scientific | 2008 |
| Environmental Concepts Limited | Extraterritorial | 2010 |
| Envision Recruitment Ltd | Administrative & support | 2025 |
| EO2 Systems Limited | Information & communication | 2019 |
| EON Accountants & Business Advisory Limited | Professional & scientific | 2019 |
| Eplatforms Ltd | Information & communication | 2000 |
| EPM DEV. (South East) Limited | Construction | 2018 |
| Epsilus Limited | Extraterritorial | 2003 |
| Epulum Ltd | Professional & scientific | 2023 |
| Equalities Sensitivity Rating Ltd | Administrative & support | 2013 |
| Equevo Limited | Professional & scientific | 2017 |
| Equi-Box Ltd | Wholesale & retail | 2011 |
| Eradipest Holdings Limited | Financial services | 2024 |
| Eradipest Ltd | Administrative & support | 1999 |
| Ergohood Ltd | Professional & scientific | 2023 |
| ERJ Estates Limited | Professional & scientific | 2005 |
| Escapist Brew Co. Ltd | Hospitality | 2018 |
| Escher Limited | Professional & scientific | 2019 |
| Espresso Link Ltd | Hospitality | 2025 |
| Essence Partnership Limited | Other services | 2009 |
| Estate to Garden Ltd | Wholesale & retail | 2015 |
| Estrans Developments (Haverfordwest) Limited | Real estate | 2013 |
| Etec Associates Ltd | Professional & scientific | 2011 |