| Ruby Cleaning Services Chesterfield Limited | Administrative & support | 2023 |
| Ruby's Bakes Ltd | Wholesale & retail | 2026 |
| Ruchi Mini Mart Limited | Wholesale & retail | 2025 |
| RUE Orange Ltd | Real estate | 2025 |
| Ruebens Recovery Services Limited | Transport & logistics | 2024 |
| Rufford View (Ollerton) Management Company Limited | Households | 2019 |
| Runfit Ltd | Extraterritorial | 2019 |
| Running at 40 Plus CIC | Other services | 2022 |
| Runswick IT Ltd | Information & communication | 2019 |
| Rurban Limited | Professional & scientific | 2003 |
| Rusisi Holdings Limited | Construction | 2020 |
| Ruskin Design Limited | Manufacturing | 2006 |
| Rusu Construction Site Services Ltd | Construction | 2025 |
| Ruszin RTP Ltd | Real estate | 2024 |
| Rutland Trading Co Limited | Wholesale & retail | 2011 |
| RVR Homes Limited | Construction | 2025 |
| RW Property Limited | Construction | 2008 |
| RWL Consulting Ltd | Professional & scientific | 2022 |
| Rworx Systems Ltd | Information & communication | 2025 |
| RWT Construction Ltd | Construction | 2020 |
| Ryestone Construction Ltd | Construction | 2025 |
| Rykneld Group Limited | Information & communication | 2016 |
| Rykneld Homes Limited | Construction | 2006 |
| S & B Simmons Properties Ltd | Real estate | 2026 |
| S & C Harper Properties Limited | Real estate | 2020 |
| S & G Site Installation Services Ltd | Construction | 2018 |
| S & J Plant Hire Limited | Construction | 2002 |
| S & L LEE Properties Ltd | Real estate | 2017 |
| S & N Brown Holdings Limited | Financial services | 2022 |
| S & NN Medical Limited | Health & social care | 2021 |
| S & R Troth Limited | Transport & logistics | 1996 |
| S & S Healthcare Limited | Health & social care | 1994 |
| S & T Audio Hire Ltd | Administrative & support | 2023 |
| S a Hall Ltd | Professional & scientific | 2022 |
| S Bellamy Ltd | Construction | 2022 |
| S Canning Contracts & SON Ltd | Extraterritorial | 2007 |
| S J Young Design Limited | Manufacturing | 1995 |
| S K C Developments Limited | Real estate | 2015 |
| S M Stroud Limited | Construction | 2000 |
| S Murby Limited | Real estate | 2008 |
| S Shrimpton Construction Services Limited | Construction | 2022 |
| S Smith Investments Ltd | Real estate | 2025 |
| S&B Rentals Ltd | Real estate | 2022 |
| S&Bh Catering (Chesterfield) Ltd | Hospitality | 2024 |
| S&Dc Ltd | Professional & scientific | 2026 |
| S&H Lineage Property Limited | Real estate | 2026 |
| S&P Cavendish Road Ltd | Hospitality | 2023 |
| S-Hall Services Ltd | Professional & scientific | 2022 |
| S-Mouzo Accountancy Ltd | Professional & scientific | 2023 |
| S-Mouzo Consulting Ltd | Administrative & support | 2017 |
| S-Mouzo Systems Ltd | Information & communication | 2023 |
| S. Brown (Paving) Limited | Construction | 1996 |
| S. O. N. Property Services Limited | Real estate | 2022 |
| S.E.G Electrical Limited | Construction | 2025 |
| S.E.Redfern Limited | Real estate | 1899 |
| S.J.Kerry Ltd | Construction | 2023 |
| S.L Conakry- Doncaster Ltd | Health & social care | 2013 |
| S.M Supplies & Imports Ltd | Wholesale & retail | 2024 |
| S.R. Hedley Plumbing & Heating Ltd | Construction | 2024 |
| S.T. Building Consultants Ltd | Professional & scientific | 2009 |
| S1 Printing and Framing Ltd | Professional & scientific | 2018 |
| S17 Pro Build Ltd | Construction | 2025 |
| S18 Counselling and Therapy Ltd | Health & social care | 2014 |
| S22-EIGHT Limited | Real estate | 2018 |
| S40 Developments Limited | Real estate | 2025 |
| S40 Fast Food Ltd | Hospitality | 2025 |
| S40 Food Ltd | Hospitality | 2024 |
| S40 Residential Ltd | Real estate | 2024 |
| S40TIME CIC | Education | 2023 |
| S41 Cars Ltd | Wholesale & retail | 2020 |
| S41 Developments Limited | Construction | 2013 |
| S41 Fast Food Ltd | Hospitality | 2025 |
| S41 Food Ltd | Hospitality | 2023 |
| S41 Motors Ltd | Wholesale & retail | 2025 |
| S41 Quality Services Ltd | Professional & scientific | 2020 |
| S410JA Food Ltd | Hospitality | 2025 |
| S42 Catering Co Limited | Hospitality | 2025 |
| S42CAFE Limited | Hospitality | 2024 |
| S43 Events Ltd | Construction | 2023 |
| S43 Food Ltd | Hospitality | 2025 |
| S43 Leisure Ltd | Professional & scientific | 2025 |
| S43 Properties Ltd | Real estate | 2024 |
| S6 Electrical Limited | Construction | 2025 |
| SA Trading Strategies Limited | Other services | 2022 |
| Sabar Investments Limited | Wholesale & retail | 2015 |
| Saber's Locum Limited | Health & social care | 2018 |
| Sabin Jones Limited | Professional & scientific | 2007 |
| Sabretooth Publishing Ltd | Information & communication | 2023 |
| Sade Enterprises Ltd | Financial services | 2024 |
| Sadel Asset Management Limited | Transport & logistics | 2022 |
| Sadel Development Management Limited | Transport & logistics | 2022 |
| Saev Logistics Ltd | Administrative & support | 2025 |
| Saf-Gard Safety Shoe Ltd | Manufacturing | 2023 |
| Safapond Direct Ltd | Construction | 2010 |
| Safe Storage Yard Limited | Other services | 2018 |
| Safedrive Driving Instructors Limited | Other services | 2012 |
| Safeline Utilities Ltd | Construction | 2024 |
| Saferail Fabrications Ltd | Manufacturing | 2022 |
| Safety R US Limited | Professional & scientific | 2024 |
| Safety S Consulting Ltd | Administrative & support | 2021 |