| Dale (Mansfield) Limited | Manufacturing | 1993 |
| Dale Edwards Limited | Construction | 2002 |
| Dale Montague Electrical Ltd | Construction | 2017 |
| Dale Travis Plastering Services Ltd | Construction | 2023 |
| Dales and Peaks Property Limited | Households | 2007 |
| Dall Scaffolding Ltd | Construction | 2025 |
| Dalton HR Solutions Ltd | Professional & scientific | 2020 |
| Dalton Roofing & Sons Ltd | Construction | 2000 |
| Daltyreseller Ltd | Professional & scientific | 2025 |
| Damar Webbing Solutions Ltd | Manufacturing | 2009 |
| Dambar Ltd | Hospitality | 2011 |
| Damn Fine Monkeys Limited | Arts & recreation | 2019 |
| DAMP2DRY Construction Limited | Construction | 2015 |
| Dampcure Chesterfield Limited | Construction | 2017 |
| Damptec Systems Limited | Construction | 2012 |
| Damrong Thai Limited | Hospitality | 2009 |
| DAN Ashcroft Design Limited | Professional & scientific | 2023 |
| DAN Packaging Ltd | Wholesale & retail | 2013 |
| Danafox Limited | Professional & scientific | 1981 |
| Dandek Building Products Limited | Construction | 2024 |
| Dandek Design Ltd | Construction | 2022 |
| Dandek Holdings Limited | Financial services | 2024 |
| Danesmoor Mini Market Ltd | Wholesale & retail | 2025 |
| Daniel Andrew Thacker Unlimited | Extraterritorial | 2024 |
| Daniel Barton Scaffolding Services Ltd | Construction | 2018 |
| Daniel Milligan Limited | Financial services | 2019 |
| Daniel Phillips Construction Ltd | Construction | 2019 |
| Daniels Goldie Limited | Hospitality | 2007 |
| Daniels Legal Recruitment Ltd | Administrative & support | 2026 |
| Danny's Sound Engineering & Social Enterprises Ltd | Health & social care | 2022 |
| Dansport Limited | Transport & logistics | 2012 |
| Danssupercars Ltd | Wholesale & retail | 2020 |
| Danwills Property Limited | Extraterritorial | 2024 |
| Dapper Digs Limited | Real estate | 2018 |
| Darby House Interiors Limited | Wholesale & retail | 2022 |
| Darbyshire Transport Limited | Transport & logistics | 2019 |
| Dark Peak Expeditions Ltd | Arts & recreation | 2025 |
| Dark Scaffolding Services Ltd | Construction | 2017 |
| Darkside Engineering 2016 Limited | Professional & scientific | 2016 |
| Darleys Restaurant Limited | Real estate | 2019 |
| Darren Weston and Family Property Limited | Real estate | 2016 |
| Darron OIL Tools Limited | Manufacturing | 2003 |
| Darron Tool and Engineering (Sheffield) Limited | Mining & quarrying | 1969 |
| Darwin and Gray Limited | Arts & recreation | 2020 |
| Dasu Engineering Limited | Extraterritorial | 2011 |
| Dasu Limited | Extraterritorial | 2011 |
| DAT Bars Ltd | Hospitality | 2020 |
| Data Ninja Limited | Information & communication | 2025 |
| Dataforge (UK) Limited | Information & communication | 2001 |
| Datagraphic Group Limited | Wholesale & retail | 1975 |
| Datagraphic Holdings Limited | Professional & scientific | 2002 |
| Datagraphic Limited | Manufacturing | 1994 |
| Datapronto Ltd | Information & communication | 2022 |
| Datatogen Limited | Wholesale & retail | 2025 |
| Datim Holdings Ltd | Financial services | 2019 |
| Datim Ltd | Manufacturing | 2013 |
| Dav's Plumbing and Heating Ltd | Construction | 2024 |
| Dav-Tec Automotive Limited | Manufacturing | 2023 |
| Dava Boutique Limited | Wholesale & retail | 2020 |
| Dave Blakey Heating Solutions Limited | Manufacturing | 2014 |
| Dave Knight Limited | Professional & scientific | 1997 |
| Davian Civil Engineering Limited | Real estate | 1958 |
| David Cole Renewables Ltd | Construction | 2023 |
| David Fenwick Limited | Construction | 2013 |
| David Sheriff Limited | Hospitality | 2018 |
| Davidson Jones Property Ltd | Construction | 2025 |
| DAW Distributions Ltd | Wholesale & retail | 2025 |
| Dawson Radford Limited | Professional & scientific | 2016 |
| DAX Simpson Fitted Furniture Ltd | Construction | 2021 |
| Day Corporation Holdings Limited | Financial services | 2024 |
| Day of the Moon Ltd | Wholesale & retail | 2024 |
| Daytona Solutions Ltd | Financial services | 2004 |
| DB Business Services (Derbyshire) Ltd | Professional & scientific | 2012 |
| DB SFX Limited | Administrative & support | 2022 |
| DB Wired Limited | Extraterritorial | 2024 |
| Db's Services Chesterfield Limited | Water & waste | 2011 |
| DBH Consultants Limited | Wholesale & retail | 2024 |
| Dbishop Engineering Ltd | Professional & scientific | 2021 |
| DC Homes Ltd | Construction | 2022 |
| DC Vickery Holding Limited | Financial services | 2025 |
| DCK & L Autos Limited | Wholesale & retail | 2007 |
| DCS Cleaning Solutions Ltd | Administrative & support | 2016 |
| DCS Servicing Ltd | Wholesale & retail | 2018 |
| DD Safety Training Limited | Other services | 2022 |
| DDR Distribution Limited | Wholesale & retail | 2025 |
| DE Ferrers Court Management Services Limited | Households | 1995 |
| DE Marca Design Limited | Manufacturing | 2022 |
| DE Veer Estates NO.2 Limited | Construction | 2022 |
| DE Veer Quarters Limited | Construction | 2018 |
| DE Wynter's Developments Limited | Construction | 2006 |
| Deacon Meadows South Residential Management Company Limited | Households | 2023 |
| Dealerwebs Ltd | Information & communication | 2009 |
| Dean Reece Limited | Construction | 2010 |
| Deaton Motor Company Ltd | Wholesale & retail | 2026 |
| Debbie's Food Ltd | Wholesale & retail | 2023 |
| Debra Jane Thacker Unlimited | Extraterritorial | 2025 |
| Debt Collection 247 Ltd | Extraterritorial | 2005 |
| Decor and Salvage Ltd | Wholesale & retail | 2011 |
| Decralite Ltd | Real estate | 2022 |
| DEE TEE Plumbing & Heating (1991) Limited | Construction | 1991 |