| Dial West Cheshire | Health & social care | 2014 |
| Diamond of Chester Camelot Ltd | Wholesale & retail | 2017 |
| Diana Beauty & Creative UK Ltd | Wholesale & retail | 2021 |
| Dice Business Limited | Professional & scientific | 2020 |
| Didcot HR Services Limited | Administrative & support | 2023 |
| Diddy Paws Limited | Agriculture & fishing | 2020 |
| Dieselbank Limited | Wholesale & retail | 1982 |
| Digby and Champ Ltd | Wholesale & retail | 2022 |
| Digi Bridge (NW) Limited | Professional & scientific | 2020 |
| Digimade Solutions Limited | Information & communication | 2024 |
| DIGIMEDIA360 Ltd | Information & communication | 2011 |
| Digipac Ltd | Professional & scientific | 2024 |
| Digital Ascension UK Limited | Financial services | 2025 |
| Digital Crux Consultants Limited | Administrative & support | 2012 |
| Digital Exposure Limited | Professional & scientific | 2008 |
| Digital Vision (North West) Limited | Other services | 2006 |
| Digital Wizards Ltd | Other services | 2017 |
| Digitalkind Limited | Information & communication | 2025 |
| Digitonomy Limited | Information & communication | 2013 |
| Dillamore Holdings Ltd | Financial services | 2019 |
| Dimech & Limmage Ltd | Real estate | 2025 |
| Dinas 6061 Limited | Financial services | 2015 |
| Dine a Design Catering Limited | Hospitality | 2020 |
| Dingle View (Management) Limited | Households | 1995 |
| Diona (UK) Limited | Information & communication | 2012 |
| Direct Services Pipes Limited | Construction | 2017 |
| Direct Shipping Solutions Ltd | Transport & logistics | 2013 |
| Direct Special Metals (Partners) Limited | Financial services | 2024 |
| Disley Marketing Limited | Information & communication | 2018 |
| Disley Theatrical Productions Ltd | Education | 2022 |
| Displace Digital Limited | Information & communication | 2019 |
| Dissociates Club Ltd | Other services | 2024 |
| District Estates Limited(The) | Real estate | 1917 |
| Divam Ltd | Health & social care | 2019 |
| Divento Limited | Information & communication | 2012 |
| Diversification Holdings Ltd | Financial services | 2013 |
| DJ Consultants Ltd | Administrative & support | 2025 |
| DJ Roofing & Property Maintenance Ltd | Construction | 2025 |
| DJ Speed Training Ltd | Professional & scientific | 2021 |
| DJ Sports and Racquets Ltd | Arts & recreation | 2025 |
| DJ Staffing Group Ltd | Administrative & support | 2022 |
| Djad Access Ltd | Professional & scientific | 2017 |
| DJH Auto Care Ltd | Wholesale & retail | 2015 |
| Djml Gunay Ltd | Other services | 2025 |
| DJS Chester Ltd | Real estate | 2023 |
| DJS Courier Services Limited | Transport & logistics | 2025 |
| DL Print Ltd | Information & communication | 2024 |
| DLA Electrical Limited | Construction | 2010 |
| DM Integration Ltd | Other services | 2015 |
| DM Utility Solutions Limited | Wholesale & retail | 2023 |
| DMA Legal Limited | Professional & scientific | 2025 |
| Dmackin Ltd | Real estate | 2021 |
| Dmat Limited | Construction | 2025 |
| Dmbenson Limited | Hospitality | 2024 |
| DMC 21 Limited | Financial services | 2021 |
| Dmcs Limited | Professional & scientific | 2002 |
| Dmcubed Limited | Information & communication | 2006 |
| DMG Motors Limited | Wholesale & retail | 1996 |
| DMG Property Development Limited | Construction | 2022 |
| Dmgs Global UK PTY Ltd | Wholesale & retail | 2021 |
| DMH Printing Limited | Manufacturing | 2025 |
| DMM Technologies Ltd | Information & communication | 2019 |
| DMO Providence Limited | Health & social care | 2020 |
| DMS1 DEN Ltd | Administrative & support | 2013 |
| DMT Healthcare Ltd | Public administration | 2025 |
| DNA Motorbikes Ltd | Wholesale & retail | 2018 |
| DNJ56 Limited | Professional & scientific | 2017 |
| DNR Endoscopy Limited | Health & social care | 2019 |
| DO Different Productions Limited | Arts & recreation | 2020 |
| Dock Stock Limited | Real estate | 2022 |
| Doctor John Limited | Health & social care | 2022 |
| Dodleston Manor Limited | Hospitality | 2024 |
| Dog King Training Ltd | Other services | 2025 |
| Dog Training With Rachael Groom Ltd | Agriculture & fishing | 2020 |
| Doghouse Daisy Ltd | Hospitality | 2015 |
| Doherty & Associates Limited | Wholesale & retail | 2002 |
| Doll Developments Limited | Real estate | 2021 |
| Doll HQ Ltd | Other services | 2020 |
| Doma Catering Limited | Hospitality | 2020 |
| Doma Events Ltd | Transport & logistics | 2024 |
| Dominus Digital Limited | Professional & scientific | 2024 |
| Donato & Sandro Limited | Real estate | 2000 |
| Doncaster Electrical Services Ltd. | Construction | 1999 |
| Done and Dusted Property Solutions Ltd | Administrative & support | 2020 |
| Done Construction and Roofing Limited | Construction | 2024 |
| Doodles Day Care Limited | Other services | 2022 |
| Door Station Limited | Wholesale & retail | 2015 |
| Dora Reverie LLP | | 2020 |
| Dora Reverie SN LLP | | 2020 |
| Dorgerove Limited | Wholesale & retail | 2018 |
| Doris Miracle Touch Ltd | Health & social care | 2025 |
| Dornlake Associates Limited | Administrative & support | 2001 |
| Dorothy Rose Occasion Wear Ltd | Wholesale & retail | 2019 |
| DOT Acquisition I Limited | Real estate | 2021 |
| DOT COM Europe Limited | Manufacturing | 2013 |
| Double Decker Bar Ltd. | Hospitality | 2014 |
| Dougherty & Allen Limited | Hospitality | 2013 |
| Douglas Mcgeorge Limited | Health & social care | 2012 |
| Douglas Williams and Co. (Electronics) Limited | Real estate | 1976 |
| Dowlish Investments Limited | Administrative & support | 2011 |