| ST Mellons 2 Limited | Extraterritorial | 2002 |
| ST Michael's Centre (Bishop's Cleeve) | Health & social care | 2014 |
| ST Michael's Orthodontics Ltd | Health & social care | 2010 |
| ST Owens Cross Battery Storage Limited | Energy | 2022 |
| ST Paul's Garage Limited | Wholesale & retail | 2002 |
| ST Philips North Cricket Club (Stanton) Limited | Arts & recreation | 2026 |
| ST Savin Associates Limited | Professional & scientific | 2010 |
| ST Webhosting Limited | Information & communication | 2015 |
| ST. Albion Limited | Construction | 1996 |
| ST. Andrew's Court (Chiswick) Management Company Limited | Households | 1974 |
| ST. Arvans Court Limited | Real estate | 1994 |
| ST. George's Gate (Freehold) Management Limited | Households | 2005 |
| ST. George's Group of Hotels (Marketing) Limited | Hospitality | 1990 |
| ST. James Clothing Ltd | Wholesale & retail | 2020 |
| ST. Kenelms Management Company Limited | Households | 1980 |
| ST. Mary's (Painswick) Residents Association Limited | Households | 2002 |
| ST. Michaels Management Company Limited | Households | 1988 |
| St.Claire Partnership Limited | Professional & scientific | 2026 |
| St.Stephen's Manor Limited | Households | 1982 |
| St.Stephens Healthcare Limited | Health & social care | 2022 |
| Stable Duck Ltd | Professional & scientific | 2025 |
| Stable Lodge B&B Ltd | Hospitality | 2019 |
| Stablemate Systems International Limited | Information & communication | 2006 |
| Stablesugarsblueprint Ltd | Health & social care | 2026 |
| Staddon Consulting Ltd | Information & communication | 2009 |
| Stae Ltd | Administrative & support | 2010 |
| Stage a Studios Limited | Information & communication | 2015 |
| Stagedoor Learning Ltd | Education | 2016 |
| Stallard & Co,(Electrical)Limited | Construction | 1965 |
| Stamford DRY Bulk LLP | | 2025 |
| Stamp Coffee Limited | Wholesale & retail | 2021 |
| Stanciu Taxi Ltd | Transport & logistics | 2026 |
| Standing Tall Films Limited | Professional & scientific | 2013 |
| Stanford Investment Holdings Limited | Financial services | 2025 |
| Stankus Ltd | Health & social care | 2019 |
| Stanley Barn Holdings Limited | Financial services | 2022 |
| Stanley Mill Enterprise Ltd | Hospitality | 2026 |
| Stanley Mill Trading Ltd | Hospitality | 2026 |
| Stanley Mill Ventures Ltd | Arts & recreation | 2026 |
| Stanley Rose Houseshares Ltd | Households | 2019 |
| Stanmer House Cheltenham (Services) Limited | Households | 1984 |
| Stanmer House Freeholders Limited | Real estate | 2003 |
| Stanton Designs Fabrication and Welding Limited | Manufacturing | 2013 |
| Stanton Under Bardon Solar Limited | Energy | 2022 |
| Stanway Hope Group Ltd | Financial services | 2026 |
| Stanway Hope Ltd | Information & communication | 2020 |
| Star Barton Ltd | Other services | 2019 |
| Star for ALL Seasons Limited | Health & social care | 2014 |
| Star Gems Ltd | Wholesale & retail | 2024 |
| Star Jump Solutions Limited | Information & communication | 2017 |
| Star Properties (MCR) Ltd | Real estate | 2012 |
| Star Scaffolding Services Limited | Construction | 2005 |
| STARGATE19 Ltd | Manufacturing | 2023 |
| Stari Fine Jewels Ltd | Manufacturing | 2024 |
| Starline Taxis Limited | Transport & logistics | 2002 |
| Starling Engineering Services Ltd | Professional & scientific | 2025 |
| Starr Holdings Limited | Real estate | 2021 |
| Start to Finish Developments Limited | Construction | 2012 |
| Station Road Garage (Bishops Cleeve) Ltd | Wholesale & retail | 2022 |
| Station Street Management Company Limited | Real estate | 2014 |
| Station Top Barbers Ltd | Other services | 2026 |
| Stationwood Property Ltd. | Construction | 2018 |
| Staverton Cars Ltd | Wholesale & retail | 2014 |
| Staverton Commercial Servicing Limited | Wholesale & retail | 1985 |
| Staverton Connection Limited | Professional & scientific | 1998 |
| Staverton Garden Ltd | Extraterritorial | 2004 |
| Staverton Powder Coatings Limited | Manufacturing | 2022 |
| Stealth Global Limited | Wholesale & retail | 2014 |
| Stealthcert (UK) Ltd | Other services | 2019 |
| Stebarane Ltd. | Households | 2023 |
| Stebles Accountancy Limited | Professional & scientific | 2002 |
| Steel House Limited | Manufacturing | 2025 |
| Steel Partitioning UK Ltd | Wholesale & retail | 2023 |
| Steelbarr Ltd | Wholesale & retail | 2002 |
| Steeplechase Distillery Limited | Manufacturing | 2020 |
| Stefan Popa Ltd | Construction | 2019 |
| Stenson Lane Bess Limited | Energy | 2023 |
| Step 1818 Limited | Hospitality | 2025 |
| Steph and Miles Ltd | Hospitality | 2017 |
| Stephanie Anne Psychology Services Ltd | Health & social care | 2022 |
| Stepping Stones Care Services ( North Wales) Limited | Extraterritorial | 2016 |
| Sterling Foundry Limited | Manufacturing | 2010 |
| Sterling Results Ltd | Construction | 2013 |
| Sterling Security Solutions (GL1) Limited | Administrative & support | 2019 |
| Sterope Limited | Professional & scientific | 2010 |
| Steve and Ben's Tattoo Company Ltd | Other services | 2021 |
| Steve Beattie Autos Limited | Wholesale & retail | 2004 |
| Steve Crozier Landscaping & Maintenance Limited | Administrative & support | 2014 |
| Steve Holland Electrical Ltd | Construction | 2001 |
| Steve Jarvis Building & Renovations Ltd | Construction | 2019 |
| Steve Kelly Design Ltd | Arts & recreation | 2009 |
| Steve Mills Roofing Specialists Limited | Construction | 2003 |
| Steve Rowley Vehicle Services Limited | Wholesale & retail | 2008 |
| Steve Savage Wealth Planning Ltd | Financial services | 2014 |
| Steve SL8TER Ltd | Professional & scientific | 2022 |
| Steve Workman Plastering Ltd | Construction | 2023 |
| Steven LEA Ltd | Financial services | 2022 |
| Steven Threadingham Builders & Designers Ltd | Construction | 2016 |
| Stevenson Building Contractors Limited | Construction | 2002 |
| Stevenson Fitness Ltd | Other services | 2024 |