| Stark North West Ltd | Construction | 2026 |
| Stark Project Management Ltd | Construction | 2026 |
| Starlight Steps Ltd | Health & social care | 2025 |
| Statham Sites Limited | Financial services | 2006 |
| STC Design and Build Limited | Construction | 2021 |
| STC Kelham Holdings Ltd | Real estate | 2025 |
| STC Property Holdings Ltd | Real estate | 2025 |
| STE Waste Management Limited | Administrative & support | 2000 |
| Steam ERA Production Ltd | Wholesale & retail | 2017 |
| Steer Lettings Ltd | Real estate | 2025 |
| Steer Property Ltd | Real estate | 2018 |
| Stella Australia Limited | Financial services | 2025 |
| Stella Invest Limited | Financial services | 2025 |
| Stella Woman Limited | Financial services | 2021 |
| Step Safely Limited | Public administration | 2024 |
| Stephen Turner Limited | Professional & scientific | 2011 |
| STEPS2CHANGE Ltd | Professional & scientific | 2000 |
| Sterling Crest Ltd | Real estate | 2026 |
| Sterling MCR Ltd | Real estate | 2022 |
| Sterling Mortgage & Financial Solutions Ltd | Financial services | 2012 |
| Sterling Supplies Group Ltd | Wholesale & retail | 2024 |
| Steron Industrial Services Limited | Manufacturing | 2025 |
| Steve Fraser Consulting Limited | Professional & scientific | 2021 |
| Steve Litt Estate Agent Ltd | Real estate | 2021 |
| Stick IT Limited | Arts & recreation | 2008 |
| Stitching Stitches Ltd | Wholesale & retail | 2021 |
| Stockport Community Foundation | Arts & recreation | 2008 |
| Stockport Community Interest Company | Professional & scientific | 2014 |
| Stockport Electrical Services Ltd | Construction | 2011 |
| Stockport Energy Partnership Limited | Extraterritorial | 2023 |
| Stockport Healthcare Limited | Wholesale & retail | 2017 |
| Stockport Muslim Foundation Limited | Other services | 2013 |
| Stockport Town Football Club Limited | Arts & recreation | 2014 |
| Stoneleigh Court Management Company Limited | Real estate | 1989 |
| Stoneleigh Ventures Limited | Real estate | 2013 |
| Stonemet Limited | Wholesale & retail | 2001 |
| Stonepail Properties Ltd | Real estate | 2021 |
| Stones Retail Limited | Wholesale & retail | 2026 |
| Stop Slugs Limited | Wholesale & retail | 2023 |
| Stopfordian Consulting Limited | Information & communication | 2022 |
| Strata IT Consulting Limited | Information & communication | 2006 |
| Stratagem Medical Solutions Limited | Health & social care | 2021 |
| Strategic Intelligence & Risk Services (Europe) Limited | Administrative & support | 2010 |
| Strategic Partners and Reliable Trade Associates Ltd | Financial services | 2024 |
| Strategic Schools Partnership Limited | Education | 2005 |
| Stratosphere Health Ltd | Public administration | 2025 |
| Strawbs Clothing Ltd | Wholesale & retail | 2025 |
| Stretch -N- Grow Ltd | Other services | 2003 |
| Stretford Carpets and Flooring Ltd | Wholesale & retail | 2019 |
| Strickland & Mather Ltd | Hospitality | 2021 |
| Stringer (Plumbing & Heating) Ltd | Construction | 2017 |
| Student Journey Advisors Global Ltd | Administrative & support | 2025 |
| Student Pages Media Group Limited | Manufacturing | 2017 |
| Studyabroadservices Ltd | Professional & scientific | 2024 |
| STW Rigging Ltd | Construction | 2025 |
| Styal Properties Limited | Real estate | 2018 |
| Style Cycle Ltd | Wholesale & retail | 2024 |
| Style Haven Limited | Wholesale & retail | 2023 |
| Stylemywardrobe Ltd | Wholesale & retail | 2025 |
| Stylo Fashion Limited | Manufacturing | 2014 |
| Stylz Vegas Limited | Wholesale & retail | 2014 |
| Sub-Pol Ltd | Hospitality | 2015 |
| Subbie Pro Limited | Wholesale & retail | 2025 |
| Sublime Translations Ltd | Other services | 2016 |
| Submiti Ltd | Information & communication | 2026 |
| Successful Minds Limited | Professional & scientific | 2015 |
| Successful Minds Online Limited | Education | 2025 |
| Suffolk Leasehold Birmingham Limited | Real estate | 2024 |
| Sugarfox Limited | Real estate | 2022 |
| Sulfit Clothing Ltd | Wholesale & retail | 2017 |
| Sultan Desserts Limited | Hospitality | 2023 |
| Sumeera Properties MCR Limited | Real estate | 2024 |
| Summerhill Freehold Company Limited | Real estate | 2021 |
| Summit Sales & Marketing Limited | Professional & scientific | 2014 |
| Sumo Desserts Ltd | Hospitality | 2026 |
| Sumo Developments Limited | Real estate | 2017 |
| Sumo Projects Adlington Limited | Construction | 2025 |
| Sump Pump Servicing Ltd | Construction | 2025 |
| Sunay Ltd | Information & communication | 2020 |
| Sunaydin Ltd | Hospitality | 2018 |
| Sunflowers Training Limited | Education | 2024 |
| Sunnahco Ltd | Wholesale & retail | 2025 |
| Sunny Force Limited | Real estate | 2021 |
| Sunny Print and Promotion Ltd | Wholesale & retail | 2016 |
| Sunset Acres Limited | Real estate | 2021 |
| Sunset Dent Limited | Other services | 2020 |
| Sunshine Art & Coffee Ltd | Construction | 2020 |
| Sunsids Ltd. | Wholesale & retail | 2025 |
| Super Deluxe Cleaning Services Ltd | Administrative & support | 2023 |
| Super Stitch Cheadle Limited | Other services | 2017 |
| Super Super Clean Ltd | Administrative & support | 2025 |
| Superselling.Com Ltd | Professional & scientific | 1999 |
| Supplylink Solutions Limited | Wholesale & retail | 2025 |
| Support Properties CIC | Real estate | 2026 |
| Support Technicians LLP | | 2014 |
| Supportis Law Limited | Professional & scientific | 2023 |
| Supportis Limited | Administrative & support | 2003 |
| Supportive Care (UK) Limited | Health & social care | 2015 |
| Supreme Realty Limited | Real estate | 2025 |
| Sure Clinical Consultancy Ltd | Professional & scientific | 2015 |