| Rosso Cleaning and Maintenance Ltd | Administrative & support | 2025 |
| Rotec Alarms Limited | Construction | 2015 |
| Rotherwood Residents Company Limited | Households | 2004 |
| Rotunda Roundhouses Limited | Construction | 2015 |
| Route 34 Limited | Administrative & support | 2014 |
| Rowcon Limited | Professional & scientific | 2014 |
| Rowcon Property Limited | Real estate | 2019 |
| Rowcon Trustee Limited | Financial services | 2026 |
| Rowlings Industries International Limited | Wholesale & retail | 1987 |
| Rowlinson Bowes Street Limited | Construction | 2018 |
| Rowlinson Constructions Limited | Construction | 1991 |
| Rowlinson Developments Limited | Construction | 2015 |
| Rowlinson Holdings Limited | Professional & scientific | 1996 |
| Rowlinson Partnerships Limited | Construction | 2015 |
| Royale Everest Property Group Ltd | Real estate | 2021 |
| Royale Everest Universal Supplier Ltd | Wholesale & retail | 2025 |
| Royles Court Management Company Limited | Households | 2001 |
| RPB Motor Bodies Ltd | Wholesale & retail | 2012 |
| RS Motorworkz Limited | Wholesale & retail | 2023 |
| RS17 Holdings Limited | Financial services | 2024 |
| RSC New Homes Limited | Professional & scientific | 2013 |
| RSR Consulting Limited | Professional & scientific | 2023 |
| RTG Enterprises R2R Ltd | Wholesale & retail | 2025 |
| RU Dark Kitchen Limited | Hospitality | 2026 |
| RU Lounge Limited | Hospitality | 2026 |
| RUB a Dubz Detailing Ltd | Wholesale & retail | 2023 |
| Rubert & Co. Limited | Manufacturing | 1941 |
| Rubina Khan Ltd | Professional & scientific | 2024 |
| Rubix Partnerships Limited | Information & communication | 2016 |
| Rude Mechanicals Limited | Manufacturing | 2018 |
| Ruhani Travels Limited | Administrative & support | 2018 |
| Rumble Portfolio Limited | Real estate | 2022 |
| Rundaz Limited | Manufacturing | 2008 |
| Runfire Films Limited | Information & communication | 2024 |
| Russell Hodson Limited | Information & communication | 2017 |
| Rusty Properties Ltd | Real estate | 2026 |
| Rutland Contracts Limited | Construction | 2026 |
| RW Direct Products Ltd | Wholesale & retail | 2023 |
| RW M&E Ltd | Arts & recreation | 2021 |
| RW Wine Ltd | Hospitality | 2025 |
| RWC Corporate Benefits Limited | Financial services | 2011 |
| RWC Corporate Holdings Limited | Financial services | 2020 |
| Rxupdate Ltd | Wholesale & retail | 2022 |
| Rybo Trading Ltd | Wholesale & retail | 2025 |
| Ryley Mount Management Company Limited | Real estate | 2013 |
| Rythmix Ltd | Arts & recreation | 2021 |
| S & K Medics Ltd | Health & social care | 2019 |
| S & L Electrical (NW) Limited | Construction | 2017 |
| S & S Evolve Ltd | Other services | 2022 |
| S B S 24 Ltd | Construction | 2025 |
| S Bayoumi Ltd | Professional & scientific | 2018 |
| S D Sales Limited | Professional & scientific | 2022 |
| S D Tyres Limited | Wholesale & retail | 2007 |
| S H Property NW Limited | Real estate | 2023 |
| S Howarth Consultancy Limited | Administrative & support | 2009 |
| S Hussain Capital Ltd | Health & social care | 2025 |
| S J Washbrook Limited | Manufacturing | 2014 |
| S M Developments Services Ltd | Construction | 2023 |
| S M H Commercial Limited | Wholesale & retail | 2006 |
| S P Contracts Northwest Ltd | Construction | 2024 |
| S P Decorating Group Ltd | Construction | 2024 |
| S P Gardening Cheshire Ltd | Administrative & support | 2023 |
| S P Landscapes Cheshire Ltd | Administrative & support | 2020 |
| S P Painting & Property Services Ltd | Construction | 2023 |
| S P Painting Cheshire Ltd | Construction | 2023 |
| S P Painting Solutions Ltd | Construction | 2024 |
| S P Platforms Ltd | Administrative & support | 2023 |
| S P Valeting Cheshire Ltd | Administrative & support | 2021 |
| S P Valeting Services Ltd | Administrative & support | 2021 |
| S S Ventures Ltd | Hospitality | 2016 |
| S Schilling Consulting Ltd | Information & communication | 2024 |
| S&D Distribution Ltd | Wholesale & retail | 2026 |
| S&N Francise Consultancy Services Ltd | Professional & scientific | 2020 |
| S&P Vale Property Ltd | Real estate | 2025 |
| S&S Cheadle Developments Ltd | Real estate | 2024 |
| S&S Investment Solution Limited | Households | 2025 |
| S. Edwards Painting & Decorating Limited | Construction | 2000 |
| S.AHMED92 Limited | Wholesale & retail | 2018 |
| S.H.O Optical Services Ltd | Wholesale & retail | 2021 |
| S2PM Limited | Real estate | 2026 |
| SA (MCR) Ltd | Wholesale & retail | 2016 |
| SA Courier Ltd | Transport & logistics | 2026 |
| SA Legal Limited | Professional & scientific | 2025 |
| SA Legal NW Ltd | Professional & scientific | 2022 |
| Sa.Gp Locum Ltd | Health & social care | 2026 |
| Saaby Ltd | Professional & scientific | 2023 |
| Saas Medical Limited | Health & social care | 2021 |
| Sabbir Optical Ltd | Wholesale & retail | 2024 |
| Saben Properties Limited | Real estate | 2016 |
| Saber Construction Ltd | Construction | 2009 |
| Sabia SH Ltd | Wholesale & retail | 2022 |
| Sadaf Network Services Limited | Wholesale & retail | 2025 |
| Safe IP Limited | Manufacturing | 2010 |
| Safe Surfacing UK Limited | Construction | 2008 |
| Safety Design Engineering Limited | Administrative & support | 2014 |
| Safety Engineering Solutions Limited | Professional & scientific | 2013 |
| Safeyah Aljabouri Art Limited | Wholesale & retail | 2018 |
| SAG Properties Ltd | Real estate | 2023 |
| Sages Homes Ltd | Administrative & support | 2017 |
| SAH Electrical & Building Contractors Ltd | Construction | 2021 |