| Vernon's Tipper & Grab Hire Limited | Construction | 2023 |
| Verto Forge Technologies Ltd | Information & communication | 2025 |
| Verve Hair (Carlisle) Limited | Other services | 2012 |
| Vesta Wealth Limited | Financial services | 2010 |
| Veterinary Consultancy Ltd | Professional & scientific | 2017 |
| Veterinary Immunogenics Limited | Manufacturing | 1992 |
| Vetreria Etrusca Limited | Other services | 2000 |
| Vetsalus Limited | Professional & scientific | 2018 |
| VGW Offshore Services Ltd | Construction | 2025 |
| Viaduct Developments Limited | Construction | 2010 |
| Vibe Salon Ltd | Other services | 2022 |
| Vibes Publishing Ltd | Wholesale & retail | 2022 |
| Vibralife Wellness Limited | Health & social care | 2009 |
| Viciunai UK & Ireland Ltd | Wholesale & retail | 2017 |
| Vigilate Ltd | Transport & logistics | 2013 |
| Vikki Swift Hearingcare Ltd | Wholesale & retail | 2019 |
| Vince and Vince Holdings Ltd | Financial services | 2024 |
| Vinden Estates Limited | Hospitality | 2011 |
| Vintage Chrome Company Ltd | Manufacturing | 2016 |
| Violet White Salons Limited | Other services | 2011 |
| Vioz Ltd | Health & social care | 2026 |
| Virginia Lodge Care Home Ltd | Health & social care | 2025 |
| Virk Brothers Limited | Hospitality | 2026 |
| Virtuoso Publishing Ltd | Professional & scientific | 2001 |
| Visionary Consultancy (Cumbria) Ltd | Professional & scientific | 2026 |
| Vistula Polish Community Association in Cumbria | Education | 2017 |
| Vitaglobe Limited | Professional & scientific | 2009 |
| Vittles Ltd | Hospitality | 2018 |
| Vizuul Limited | Information & communication | 2017 |
| VL Consultancy Europe Limited | Professional & scientific | 2021 |
| Vlchin Investment Limited | Real estate | 2022 |
| VLT Limited | Other services | 2010 |
| Void to Vortex Limited | Information & communication | 2016 |
| Volteris Group Ltd | Information & communication | 2025 |
| Volunteers in Public Safety Research Limited | Professional & scientific | 2015 |
| Vortex Hydra (UK) Limited | Manufacturing | 2000 |
| VR Gateway Limited | Information & communication | 2019 |
| VSL Support Limited | Extraterritorial | 2010 |
| W a Developments Holdings Limited | Professional & scientific | 2006 |
| W B Brown Properties Limited | Real estate | 2024 |
| W Bimson & Sons Limited | Real estate | 1998 |
| W C Little & SON Limited | Agriculture & fishing | 2017 |
| W H Fisher & SON Ltd | Agriculture & fishing | 2017 |
| W L Musgrave & Sons | Agriculture & fishing | 2013 |
| W S Engineering Services Limited | Construction | 2005 |
| W Swainson & SON Ltd | Agriculture & fishing | 2023 |
| W T Woodley Ltd | Extraterritorial | 2023 |
| W W Windows Carlisle Limited | Construction | 2013 |
| W. Byers Limited | Wholesale & retail | 2012 |
| W. Vasey & Sons (Carlisle) Limited | Wholesale & retail | 1956 |
| W. W. Builders (Cumbria) Limited | Construction | 2025 |
| W.A. Developments International Limited | Construction | 2001 |
| Waldegrave and Prescott Management Limited | Households | 2004 |
| Walker Brothers (Timber Frames) Ltd | Manufacturing | 2003 |
| Walton Goodland Limited | Real estate | 2004 |
| Walton's Vegetables Limited | Real estate | 2013 |
| Wannop Fairfield Limited | Real estate | 2022 |
| Wannop Netherby RD Limited | Construction | 2022 |
| Wapping Property Limited | Real estate | 1984 |
| Ward Building Services Engineering Limited | Professional & scientific | 2007 |
| Ward Group Limited | Financial services | 2015 |
| Ward Meadows Plant (Carlisle) Limited | Wholesale & retail | 2006 |
| Wardman 2011 Limited | Extraterritorial | 2011 |
| Wardman Investment Group Limited | Extraterritorial | 2011 |
| Warwick Bridge Taxis Ltd | Transport & logistics | 2020 |
| Warwick Eden Limited | Hospitality | 2006 |
| Warwick Paving & Groundworks Limited | Construction | 2020 |
| Warwick-On-Eden Playground | Arts & recreation | 1999 |
| Waseem Construction Ltd | Construction | 2024 |
| Waste Transfer Services Ltd | Water & waste | 2015 |
| Watchtree Nature Reserve Limited | Arts & recreation | 2004 |
| Water ST Ltd | Transport & logistics | 2022 |
| Waterhead Close Management (Ambleside) Limited | Households | 2014 |
| Waterloo Heat Network Limited | Construction | 2025 |
| Waters Edge (Whitehaven) Flat Management Company Limited | Households | 2015 |
| Waters Edge (Whitehaven) Management Company Limited | Households | 2014 |
| Waterside (Cottam) (2-18 Larch Lane) Management Company Limited | Households | 2016 |
| Waterside (Cottam) (29-39 Copper Beech Lane) Management Company Limited | Real estate | 2019 |
| Waterside (Cottam) (37-45 Larch Lane) Management Company Limited | Real estate | 2019 |
| Waterside (Cottam) Management Company Limited | Households | 2016 |
| Waterside Ullswater Ltd | Hospitality | 2025 |
| Waterton Court Management Company Limited | Households | 2004 |
| Watsign Limited | Professional & scientific | 2005 |
| Watson-Clark Specialist Cars Limited | Wholesale & retail | 2008 |
| Waugh Developments (Portfolio) Ltd | Real estate | 2022 |
| Waugh Developments Ltd | Real estate | 2018 |
| Waugh Estates Ltd | Real estate | 2021 |
| Wavell Properties Ltd | Real estate | 2020 |
| Waver Court Management Company Limited | Households | 2005 |
| Waverton Properties Limited | Real estate | 2021 |
| Waves Education Ltd | Education | 2024 |
| Wayne LEE Motorsports Limited | Wholesale & retail | 2007 |
| Wayout Wifi Limited | Wholesale & retail | 2013 |
| WB Anderson Holdings Limited | Financial services | 2013 |
| WB Deliveries Ltd | Transport & logistics | 2021 |
| WB Roofing and Building Ltd | Construction | 2026 |
| WBH Construction Ltd | Construction | 2016 |
| Wbsa Limited | Construction | 2015 |
| WE ARE Web Ltd | Administrative & support | 2013 |
| WE Only Print Limited | Manufacturing | 2025 |